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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
shape increases » showed increases (Expand Search), sharp increase (Expand Search), disease increases (Expand Search)
small decrease » small increased (Expand Search)
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19081
Table 5_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls
Published 2025“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”
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19082
Table 1_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease: a m...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
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19083
Table 1_Influence of indigenous non-Saccharomyces yeast strains on the physicochemical and sensory properties of wine fermentation: a promising approach to enhancing wine quality.d...
Published 2024“…High-Performance Liquid Chromatography analysis revealed that while tartaric acid levels remained constant, malic acid content decreased, and acetic acid was produced by all strains. …”
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19084
Table 1_The interaction between temperature and rainfall determines the probability of tropical forest fire occurrence in Hainan Island.docx
Published 2025“…The results show that: (1) climatic factors contribute most significantly to the tropical forest fire probability, followed by human activities and topography, while vegetation factors (i.e., normalized difference vegetation index) made no significant contribution; (2) temperature and rainfall are the dominant factors influencing fire probability, with rising temperatures and decreasing rainfall substantially increasing the forest fire hazard; and (3) both logistic regression and random forest are reliable for predicting tropical forest fire hazards, but random forest demonstrates greater adaptability. …”
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19085
Data Sheet 1_The relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.zip
Published 2024“…Four of these factors were significantly causally related to the incidence of heart failure: CXCL9 and IFN-γ as promotive factors, and LIFR and UPA as potential protective factors. …”
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19086
Image 2_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg
Published 2025“…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”
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19087
Table 4_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.docx
Published 2025“…</p>Results<p>Both the low-frequency electroacupuncture group and the high-frequency electroacupuncture group significantly reduced writhing scores, increased spleen index, decreased prostaglandin PGF2α and COX-2 levels, and increased prostaglandin PGE2 and β-EP levels to varying degrees.…”
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19088
Data_Sheet_1_Air pollutants and ovarian reserve: a systematic review of the evidence.PDF
Published 2024“…Background<p>Growing evidence indicates an association between ambient air pollution and decreased human reproductive potential. This study aims to systematically review the association between air pollutants and female ovarian reserve.…”
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19089
Data Sheet 1_Craving on the move: targeting smoking memories with a novel 3MDR–smoking cessation protocol.pdf
Published 2024“…Smoking cue–induced craving and physiological measures were assessed at baseline (T0) and 1 day after the intervention (T4), and smoking behavior was measured at T0 and 2-week (FU1) and 3-month (FU2) follow-up.</p>Results<p>Significant decreases in cue-induced craving from T0 to T4 and daily cigarette use from T0 to FU1 and FU2 were observed but not differ between the two experimental groups. …”
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19090
Image_4_Effect of probiotic supplementation combined with bismuth-containing quadruple therapy on gut microbiota during Helicobacter pylori eradication: a randomized, double-blind,...
Published 2024“…After treatment, the GSRS score decreased significantly in the probiotic group (p = 0.039). …”
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19091
DataSheet1_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.pdf
Published 2024“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”
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19092
Table 1_The effect of omega-3 supplementation on metabolic, inflammatory and oxidative stress biomarkers in pregnant women: a systematic review and meta-analysis.docx
Published 2025“…However, triglyceride (SMD = −0.96, 95% CI: −1.77, −0.16) and CRP (SMD = −0.98, 95% CI: −1.86, −0.11) significantly decreased, and HDL-C cholesterol levels significantly increased (SMD = 0.72, 95% CI: 0.21, 1.22) following omega-3 supplementation.…”
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19093
Data Sheet 1_Increased risk of deep vein thrombosis, pulmonary embolism, and all-cause mortality in chronic venous disorder: a large-scale retrospective cohort study.docx
Published 2025“…Background<p>Chronic venous disorder (CVD), often overlooked as a significant medical burden, has recently been linked to severe health risks, especially deep vein thrombosis (DVT), and pulmonary embolism (PE). …”
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19094
Image7_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
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19095
Data Sheet 1_Identification and management of a novel Danshen leaf anthracnose caused by Colletotrichum karstii in Salvia miltiorrhiza Bunge in China.pdf
Published 2025“…<p>Danshen (Salvia miltiorrhiza Bunge), a member of the genus Salvia within the Lamiaceae family, holds significant economic and medicinal value. Regrettably, the emergence of a novel leaf anthracnose in 2020 has significantly impacted its cultivation, leading to decreased yield and compromised quality. …”
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19096
Table 3_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.docx
Published 2025“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”
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19097
Data Sheet 3_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
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19098
Table 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx
Published 2025“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”
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19099
Table 3_Association between cardiovascular health and markers of liver function: a cross-sectional study from NHANES 2005–2018.docx
Published 2025“…</p>Results<p>Linear regression analysis showed that each 1-point increase in CVH score was significantly associated with decreased levels of liver enzymes [ALT: −0.200 U/L (95% CI: −0.223, −0.176), AST: −0.043 U/L (−0.062, −0.024), GGT: −0.453 U/L (−0.509, −0.397), ALP: −0.310 U/L (−0.340, −0.281)] and increased levels of albumin [0.040 g/dL (0.036, 0.045)] and AST/ALT ratio [0.0056 (0.0051, 0.0061)]. …”
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19100
Table 1_Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.docx
Published 2025“…Introduction<p>Lipid accumulation and foam cell formation are significant features that expedite the progression of atherosclerosis (AS). …”