Supplementary file 2_Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy.pdf by Rui Zhang (13940)

“…And the network analysis results speculated that Calycosin (Cal), a major component of AM-CO, could ameliorate DN injury by regulating autophagy through modulating the PI3K-AKT signaling pathway. In vivo experiments showed that AM-CO could induce autophagy, an increase in LC3II expression and a decrease in P62 expression. …”

Image 5_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Image 2_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Image 4_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Image 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Table 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.docx by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Data Sheet 1_Longitudinal associations between the COVID-19 pandemic and sleep characteristics in children and parents.docx by Deborah Wernecke (22090103)

“…Multivariable mixed models revealed better sleep quality (lower CSHQ total scores) among boys during the COVID-19 pandemic compared to before and after. Daytime sleepiness decreased among boys and girls, while no significant changes were found for sleep duration and sleep latency. …”

Table 1_Microbiological effect of topically applied Weissella cibaria on equine pastern dermatitis.docx by Eva Styková (20507045)

“…The application of the W. cibaria strain was associated with a significant decrease of the genera Staphylococcus, Moraxella, and Rothia in the proliferative group and with a decrease of Streptococcus and Clostridium in both exudative and proliferative groups. …”

Supplementary Material for: Analysis of retinal and choroidal microvasculature in systemic sclerosis using optical coherence tomography angiography: A systematic review and meta-an... by Lohrasbi F. (20017569)

“…Meta-analysis findings revealed a significant decrease in vessel densities in both the superficial and deep capillary plexuses (SCP and DCP) among SSc patients compared to controls. …”

Image1_ASC speck serum concentrations, a component of sterile cellular inflammation, are associated with individual cardiopulmonary capacity.JPEG by Alexander Kogel (13296595)

“…Overall, ASC speck concentrations showed no significant change after CPET (7.0 ± 4.5 vs. 8.0 ± 5.4 ASC specks/µL, p = 0.3). …”

Supplementary files by Ali nasith (20645786)

“…Likewise, with the use of games/internet, there was a decrease in the tendency of addiction in the religious group. …”

Supplementary Material for: Collagen I Derived Extracellular Matrix Motifs Alter Fibroblast Regenerative Response by figshare admin karger (2628495)

“…Soluble free mECMs induced changes in fibroblast phenotype as indicated by a decrease in proliferation, decrease in nuclei area, and increase in percentage of elongated cells. …”

Data_Sheet_1_Exercising educational equity using California’s physical fitness data: a call for more school physical fitness programs, data, and research.docx by Da’Shay Templeton (19802262)

“…The lack of safe and affordable options for physical activity coupled with the significant decrease in physical activity rates among most American children underscores the need for programs, data, and research on physical fitness in schools, where children spend a significant amount of their time. …”

Table3_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…Furthermore, specific mitochondrial variants showed significant associations with T2D risk after adjustment for relevant covariates, and some variants were exclusively found in T2D patients.…”

Image 4_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Levels of specific antibodies (anti-CII IgG, anti-CII IgG1, and anti-CII IgG2a) and cytokine IL-17A in serum, as well as cytokines (TNF-α and IL-1β) in the synovial fluid of B. animalis BD400-treated CIA rats, were significantly reduced (p < 0.05). The gene expression levels of intestinal barrier proteins (occludin-1, MUC-2, and ZO-1) showed a significant increase (p < 0.05) in B. animalis BD400-treated CIA rats. …”

Image 2_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Levels of specific antibodies (anti-CII IgG, anti-CII IgG1, and anti-CII IgG2a) and cytokine IL-17A in serum, as well as cytokines (TNF-α and IL-1β) in the synovial fluid of B. animalis BD400-treated CIA rats, were significantly reduced (p < 0.05). The gene expression levels of intestinal barrier proteins (occludin-1, MUC-2, and ZO-1) showed a significant increase (p < 0.05) in B. animalis BD400-treated CIA rats. …”

Table4_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…Furthermore, specific mitochondrial variants showed significant associations with T2D risk after adjustment for relevant covariates, and some variants were exclusively found in T2D patients.…”

Table 1_Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis.docx by Lin Shi (65217)

“…</p>Results<p>Heart dysfunction and blood glucose showed a significant negative indirect effect on VWF through the overall leukocyte levels (indirect effect = −0.119 and −0.118, p < 0.05). …”

Image 1_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Levels of specific antibodies (anti-CII IgG, anti-CII IgG1, and anti-CII IgG2a) and cytokine IL-17A in serum, as well as cytokines (TNF-α and IL-1β) in the synovial fluid of B. animalis BD400-treated CIA rats, were significantly reduced (p < 0.05). The gene expression levels of intestinal barrier proteins (occludin-1, MUC-2, and ZO-1) showed a significant increase (p < 0.05) in B. animalis BD400-treated CIA rats. …”

Table 3_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.docx by Yang Yang (45629)

“…Levels of specific antibodies (anti-CII IgG, anti-CII IgG1, and anti-CII IgG2a) and cytokine IL-17A in serum, as well as cytokines (TNF-α and IL-1β) in the synovial fluid of B. animalis BD400-treated CIA rats, were significantly reduced (p < 0.05). The gene expression levels of intestinal barrier proteins (occludin-1, MUC-2, and ZO-1) showed a significant increase (p < 0.05) in B. animalis BD400-treated CIA rats. …”