-
1
-
2
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
3
Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting
Published 2025“…The computational results demonstrate the superiority of the proposed models through a comparative analysis against state-of-the-art approaches across fifteen significant wave height time series, validated by three error metrics and a statistical test.…”
-
4
Treating Cancers Using Nature’s Medicine: Significance and Challenges
Published 2021“…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …”
-
5
Impact of aluminium acetate particles size on the gelation kinetics of polyacrylamide‐based gels: Rheological and molecular simulation study
Published 2023“…Using 7 wt.% PAM/1 wt.% AlAc with sizes of 25 and 48 μm revealed a crosslinking time of 17 and 115 min, respectively. …”
-
6
Detection of statistically significant network changes in complex biological networks
Published 2017“…The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …”
-
7
W-Transformers : A Wavelet-based Transformer Framework for Univariate Time Series Forecasting
Published 2022“…We present a novel framework for univariate time series representation learning based on the wavelet-based transformer encoder architecture and call it W-Transformer. …”
Get full text
-
8
-
9
-
10
Special Issue: Empowering eHealth with Smart Internet of Things (IoT) Medical Devices
Published 2019“…IoT helps to store data for millions of patients and perform analysis in real-time, promoting an evidence-based medicine system. …”
-
11
Optimum sizing of steam turbines for concentrated solar power plants
Published 2012“…The results indicate that the estimated efficiency and the expected specific capital cost of the power block are very important criteria in choosing the best steam turbine size of a CSP plant. For capacity sizes of 10kWe up to 50MWe, the steam turbine efficiency increases and the steam turbine expected specific capital cost of the power block decreases at a high rate, whereas for larger sizes they remain almost constant. …”
Get full text
article -
12
-
13
-
14
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
-
15
Non-Linear Time History Analysis of Moment Frame Structure with Performance-Based Approach on Different Concrete Compressive Strengths
Published 2023“…Keywords: Performance Based Design, PBD, Perform3D, time history analysis, pushover analysis, nonlinear concrete, concrete compressive strength…”
Get full text
-
16
-
17
-
18
Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
-
19
Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
-
20
Time to diagnose and time to surgery in patients presenting with necrotizing fasciitis: a retrospective analysis
Published 2025“…While early surgical intervention is vital, our findings suggest that the time to diagnosis and subsequent resuscitation efforts may significantly impact survival. …”