Additional file 6 of NSDHL contributes to breast cancer stem-like cell maintenance and tumor-initiating capacity through TGF-β/Smad signaling pathway in MCF-7 tumor spheroid by So-Hyun Yoon (5353250)

“…Supplementary Material 6: Figure S6. A-83-01 (50 µM) decreased the phosphorylation of both SMAD2 and SMAD3 but did not show significant toxicity in MCF-7-spheroids. …”

Data Sheet 1_The effect of vagus nerve stimulation on heart rate and respiration rate and their impact on seizure susceptibility in anaesthetized rats under pentylenetetrazol.pdf by Javier Chávez Cerda (20913026)

“…Results indicate that the stimulation significantly decreased the heart rate below baseline levels for standard VNS (−120.0 ± 69.1 bpm) and breathing-synchronized VNS (−84.9 ± 61.0 bpm), overcoming the heart rate increasing effect of PTZ infusion observed in the sham VNS (+79.2 ± 35.5 bpm), and there was no recovery during OFF periods. …”

Reliable high-PAP-1-loaded polymeric micelles for cancer therapy: preparation, characterization, and evaluation of anti-tumor efficacy by Fang Ye (112854)

“…These self-assembled micelles exhibited high entrapment efficiency (91.35%) and drug loading level (8.30%). As pH decreased, the micelles exhibited a significant increase in particle size and zeta potential, accompanied by a surge in PAP-1 release. …”

<b>Regional asymmetries in dissolved organic carbon response to nitrogen addition rather than soil organic carbon and microbial biomass carbon</b> by Andong Cai (5237024)

“…Our results revealed asymmetrical effect of nitrogen addition on soil DOC across humid and non-humid regions rather than microbial biomass carbon (MBC) and SOC. N addition significantly decreased soil DOC (-2.49%) in humid regions, while increasing it (7.30%) in non-humid regions. …”

Table 1_Effect of Ebenatide on glycemic metabolism and body fat in patients with type 2 diabetes mellitus.docx by Cheng-lan Xu (21562694)

“…</p>Results<p>The Ebenatide group showed significantly lower in hemoglobin A1c (HbA1c), mean blood glucose (MBG), time above range (TAR) and standard deviation (SD), along with improvement of time in range (TIR) at Week 24 and Week 52 compared to baseline (P<0.05). …”

Data Sheet 1_Global, regional, and national time trends in falls and their predictions: an age-period-cohort analysis of the Global Burden of Disease Study 2021.pdf by Huan Jiang (1672375)

“…The cohort effect shows a trend of increasing first (RR: 1.02–1.18) and then decreasing (RR: 1.18–0.40). …”

Impact of Carbene Ligands on the Properties and Reactivity of Diazoboranes by Chonghe Zhang (10798948)

“…The results demonstrate that increasing carbene π-acidity weakens the B–N bond while strengthening the N–N bond, significantly decreasing thermal stability. Kinetic studies reveal that less π-acidic carbenes promote a second-order decay mechanism, leading to dibora-azine formation, whereas more π-acidic carbenes favor first-order dinitrogen dissociation, facilitating borylene generation. …”

Comparative metabolome analysis of case (fearful dogs) versus controls. by Luigi Sacchettino (12288497)

“…The red and green dots represent the significant increased and decreased metabolites, respectively. …”

Data Sheet 1_Alternate wetting and drying irrigation at tillering stage enhances the heat tolerance of rice by increasing sucrose and cytokinin content in panicles.docx by Ti Gao (21442307)

“…AWD increased the expression of CTK biosynthesis genes (IPT, CYP735A, LOG) and decreased that of CTK degradation gene CKX in roots and panicles under HDT, while enhanced the xylem sap flow rate and contents of CTKs, IAA, and GAs in panicles. …”

Droperidol is associated with reduced length of stay in the treatment of cannabinoid hyperemesis syndrome by Geoffrey S. Kelly (21537766)

“…Droperidol was used in 77 (36.5%) of encounters at a median dose of 1.25 mg. The length of stay was significantly reduced in the droperidol group (409 min versus 641 min). …”

Supplementary file 1_Collaborative optimal operation control of HVAC systems based on multi-agent.docx by Chen Fu (165356)

“…<p>The HVAC system of public buildings, as a thermostatically controlled load, accounting for a relatively significant proportion of building energy consumption. …”

Effects of incubation temperature and sex on local and systemic immune parameters in broiler chickens by K. Papanikolaou (22476654)

“…It was hypothesised that increased or decreased incubation temperature could support the developing immune system.…”

Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Image 1_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. by Weiran Huang (8934899)

“…Within 6 hours, the difference was highly significant with a p-value < 0.0001. Later, at 7–9 hours, the OHT groups continued to show significant differences compared to controls, with a p-value of 0.0004. …”

Image 1_Emphysema-related mortality rates in the U.S. from 1999 to 2022.pdf by Alexandra Brown (225908)

“…</p>Discussion<p>Emphysema-related deaths in the United States decreased overall between 1999 and 2022, likely a result of a greater emphasis on health education concerning the significant dangers of smoking and policy changes that made cigarettes less accessible and less affordable, and more available access to resources and support networks.…”

Table 1_Immigration reduces selection in water microbial community assembly.xlsx by Fen-Guo Zhang (736948)

“…However, on the 60th day, diversity significantly increased. The variation explained by the environment substantially decreased from the 13th to the 60th day. …”

Data Sheet 7_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The results show that (1) there are three stages, namely, compression, pore development, and post-peak failure, which promote the development and evolution of medium pore and macropores in lignite. (2) Under uniaxial compression, the permeability of the lignite sample shows a “V-shaped” trend, first decreasing and then increasing. …”

Data Sheet 4_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The results show that (1) there are three stages, namely, compression, pore development, and post-peak failure, which promote the development and evolution of medium pore and macropores in lignite. (2) Under uniaxial compression, the permeability of the lignite sample shows a “V-shaped” trend, first decreasing and then increasing. …”

Data Sheet 3_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The results show that (1) there are three stages, namely, compression, pore development, and post-peak failure, which promote the development and evolution of medium pore and macropores in lignite. (2) Under uniaxial compression, the permeability of the lignite sample shows a “V-shaped” trend, first decreasing and then increasing. …”