Fragment-based design of small molecule PCSK9 inhibitors using simulated annealing of chemical potential simulations by Frank Guarnieri (2181644)

“…To identify such fragments, Simulated Annealing of Chemical Potential (SACP) fragment simulations were run on multiple PCSK9 structures, using optimized partial charges for the protein. We designed a small molecule, composed of several fragments, predicted to interact at two sites on the PCSK9. …”

Inhibition controls levels of pattern separation in granule cells through different neural codes. by Antoine D. Madar (6619286)

Data_Sheet_1_The Benefit of Hedgerow Access on the Health and Growth Rate of Pasture Raised Broiler Chickens.docx by Eilea Delgadillo (11187690)

“…Research into simple methods to optimize the growth and health of pasture-raised poultry can help small farmers maximize meat yields and decrease the morbidity and mortality of their flock, ultimately leading to higher profit margins and improved animal welfare. …”

Table 1_Study on the effect of GCY-12 gene on albendazole sensitivity of Haemonchus contortus by RNA interference.xlsx by Xindi Chen (6485522)

“…Introduction<p>Haemonchus contortus (H. contortus) is a common gastrointestinal nematode in small ruminants, posing a significant threat to the livestock industry. …”