Image 2_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png by Xiaofang Chen (256976)

“…</p>Results<p>In 2019, lead exposure-related ischemic stroke caused a significant disease burden, with males and middle-aged/older adults disproportionately affected. …”

Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx by Yuchen Liang (8596404)

“…<p>Lavender (Lavandula angustifolia Mill.) is a valuable aromatic plant with significant commercial importance. However, cold stress–one of the primary abiotic factors impacting sugar metabolism–adversely affects its agricultural productivity in Northeast China. …”

Supplementary file 1_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx by Yi-Chang Zhao (14080107)

“…CRP levels decreased significantly (mean difference = 14.91; 95% CI: 2.79–27.02), while changes in PCT, WBC, and neutrophil ratios were non-significant. …”

5OMV Inhibits HMGB1-Induced Microvascular Branch Formation in Rat Abdominal Aortic Rings. by Wenyue Hou (10203722)

“…Mean values showing significant differences between the control group and the HMGB1-treated group are indicated by *(<i>P</i> < 0.05) or ** (<i>P</i> < 0.01). …”

Data Sheet 1_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf by Sunil Dhungel (21449354)

“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”

Data Sheet 1_Effects of irrigation and fertilization management on kiwifruit yield, water use efficiency and quality in China: A meta-analysis.zip by Yuehua Ding (22434916)

“…However existing kiwifruit water-saving and fertilizer-reduction studies showed significant contradictions in the results of water and fertilizer management. …”

Table 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.xlsx by Lingxin Zheng (14554387)

“…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …”

Table 2_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx by M. Virginia Martín (6321047)

“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”

Table 1_Global, regional, and national burden of liver cancer in adolescents and young adults from 1990 to 2021: an analysis of the global burden of disease study 2021 and forecast... by Jingyu Wen (13913130)

“…East Asia bears the highest burden, with males experiencing significantly higher rates than females. The burden increases with age, peaking at 35–39 years. …”

Image 7_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg by Yue Fu (64387)

“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”

Data Sheet 1_Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice.zip by Jiyao Zhao (10505867)

“…WB showed that P62 was significantly increased and RILP was significantly decreased in diabetic mice subjected to I/RI compared to healthy mice. …”

Data Sheet 2_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf by Sunil Dhungel (21449354)

“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”

Image 1_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg by Yue Fu (64387)

“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”

Table 1_A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial.docx by Li Zhang (8200)

“…</p>Results<p>In addition to significant within group improvements over time for both groups, OLS linear regression with Full Information Likelihood Estimation revealed a statistically significant between group treatment effects across outcome domains, including psychological distress, b = 22.60, p < 0.001, g = 11.34, somatic symptoms, b = 6.79, p < 0.001, g = 6.56, depressive symptoms, b = 8.15, p < 0.001, g = 8.19, and anxiety symptoms, b = 7.69, p < 0.001, g = 8.23.…”

DataSheet1_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip by Timothy G. Wanninger (20296455)

“…The significant changes that occurred in both the liver and lung were more pronounced in the liver.…”

DataSheet2_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip by Timothy G. Wanninger (20296455)

“…The significant changes that occurred in both the liver and lung were more pronounced in the liver.…”

Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx by Susan Carroll (17468)

“…Participants reported significant benefits from nature.</p>Discussion<p>Overall, the results showed that connecting with nature significantly contributes to flourishing in highly sensitive individuals, particularly in middle to older age. …”

Image 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.tif by Lingxin Zheng (14554387)

“…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …”

Data Sheet 2_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip by Siqi Ye (9350531)

“…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …”

Data Sheet 1_Association of dietary index for gut microbiota and cardiovascular diseases in American adults: evidence from National Health and Nutrition Examination Survey 1999–201... by Hong Luo (205745)

“…Background<p>As a significant health burden, cardiovascular disease (CVD) contributes substantially to global disease and death rates. …”