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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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small decrease » small increased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
small decrease » small increased (Expand Search)
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20901
Supplementary Material for: DOT1L regulates cellular senescence during the progression from acute kidney injury to chronic kidney disease via the micro-222-5p/WNT9B signaling pathw...
Published 2025“…Results: The results demonstrated that in vivo inhibition of DOT1L significantly reduced cellular senescence and improved renal tubular injury and interstitial fibrosis. …”
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20902
E9.5 <i>TRAF7</i><sup><i>KO</i></sup>-asterisk vs. WT DEGs.
Published 2024“…Histological examination of anterior thalamic nuclei demonstrated decreased myelination of anteroventral nuclei but not of anterodorsal nuclei in P23 <i>Rik</i><sup><i>null</i></sup> mice. …”
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20903
Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis
Published 2025“…Additionally, low mechanics significantly diminishes NCOA4, pivotal in mediating FTH1 phase separation-induced ferritinophagy. …”
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20904
DNA damage protecting effects of EAExCC.
Published 2025“…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”
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20905
Table 1_The prevalence and correlates of falls in adults with attention-deficit/hyperactivity disorder: cross-sectional study.docx
Published 2025“…Studies have shown that individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) have decreased balance. Poor balance is associated with increased risk of falls. …”
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20906
Table 1_Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.docx
Published 2025“…Machine learning approaches highlighted 7 critical genes, with JUN emerging as the core gene. JUN levels were significantly decreased during osteogenic differentiation, showing high diagnostic accuracy (AUCs: 0.977-1.000). …”
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20907
Data Sheet 1_Speaker-story mapping as a method to evaluate audiovisual scene analysis in a virtual classroom scenario.pdf
Published 2025“…Results indicate that the experimental condition significantly influenced task performance, mental load, and user behavior but did not affect perceived simulator sickness and presence. …”
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20908
Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx
Published 2025“…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…”
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20909
Image 1_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif
Published 2025“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”
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20910
XRD diffraction pattern spectra of PFAgNPs.
Published 2025“…The no observed adverse effect level was 50 mg/kgBW, the lowest observed adverse effect level was 100 mg/kgBW, and median lethal dose (LD<sub>50</sub>) was 1000 mg/kg. The PFAgNPs significantly decreased (<i>P</i> < 0.05) serum proteins, cholesterol, estrogen and progesterone alongside preservation of the histoarchitecture of the uterus. …”
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20911
Model framework.
Published 2024“…This study underscores the significance of the COVID-19 vaccine booster policy. …”
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20912
Data Sheet 2_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf
Published 2025“…Beta-diversity of the cecal microbiome was significantly altered as a function of the four test diets. …”
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20913
Improved estimation of soil organic carbon stock in subtropical cropland of Southern China based on digital soil mapping and multi-sources data
Published 2025“…Additionally, the mean value of SOCD significantly decreased from 3.23 in the 1980s to 2.95 kg m<sup>−2</sup> in the 2010s. …”
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20914
Image 1_The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis.tif
Published 2025“…</p>Results<p>Compared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. Conversely, decreased activity was found in the right cerebellum (lobule IX) and left cerebellum (lobules VIII and IX). …”
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20915
DataSheet1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.docx
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”
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20916
Table_1_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H...
Published 2024“…Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…”
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20917
Table 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx
Published 2025“…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
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20918
Table 7_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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20919
Image 1_COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis.tif
Published 2025“…</p>Results<p>COP1 was significantly correlated with poor patient prognosis. …”
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20920
Table 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.xlsx
Published 2025“…</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”