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20201
Supplementary file 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.pdf
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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20202
Image 2_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.png
Published 2025“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”
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20203
Table_1_Effect of diet low in omega-6 polyunsaturated fatty acids on the global burden of cardiovascular diseases and future trends: evidence from the Global Burden of Disease 2021...
Published 2025“…The most significant effects were seen in individuals aged 75 and older, with a higher disease burden noted in males. …”
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20204
Video 3_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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20205
Supplementary Material for: The Association Between Tumor Necrosis Factor-Alpha Inhibitor Use and Dementia Risk in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-...
Published 2025“…Also, the subgroup analyses indicated that TNFi use was associated with a decreased dementia risk in older adult patients with a mean age of ≥65 years at enrollment (HR = 0.86, 95% CI 0.80-0.92) and in TNFi new users (HR = 0.86, 95% CI 0.80-0.92). …”
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20206
Table 2_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.docx
Published 2025“…No significant differences were observed in other indicators.…”
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20207
Supplementary Material for: Comprehensive Genetic Analysis Exploring Sedentary Lifestyle, Physical Activity, and Respiratory Diseases: A Bidirectional Mendelian Randomization with...
Published 2024“…A genetic predisposition to SBW was associated with a decreased risk of nasal polyps (OR = 0.60, 95% CI = 0.423-0.86, p = 0.005). …”
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20208
Supplementary file 2_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co...
Published 2025“…</p>Results<p>The growth performance did not show significant differences according to the feed additives. …”
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20209
<b>Efficacy of strength and conditioning training on dance injury, physical fitness and dance performance in Chinese pre-professional dancers</b>
Published 2025“…Results: The intervention group demonstrated significant increases in physical fitness (p<0.001), but their dance performance data remained statistically unchanged (p>0.05). …”
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20210
Table 3_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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20211
Data Sheet 1_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx
Published 2025“…</p>Discussion<p>The capacity for infectious disease prevention and control among Guangxis grassroots hospital physicians has significantly improved following COVID-19. The high engagement in related training and emergency response efforts reflects a strong sense of professional identity and commitment. …”
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20212
Table 1_Integrative physiological, biochemical, and metabolomic analyses reveal complex drought and zinc stress tolerance in a novel Miscanthus hybrid.xlsx
Published 2025“…Fatty acid derivatives, nitrogen-containing compounds, hormone/signal-related compounds (jasmonate), and secondary metabolites (phenylpropanoids, N-containing compounds, and terpenes) showed significant (p < 0.05) abundance changes in response to D, Zn, and its combination D + Zn stress. …”
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20213
Data Sheet 1_Genome-wide development of SSR molecular markers for modern sugarcane cultivars.docx
Published 2025“…In this study, We searched for and identified SSR loci within the genomes of 14 Poaceae plants. Notably, a significant positive correlation (r = 0.958) was detected between genome size and the number of SSRs. …”
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20214
Data Sheet 1_Self-esteem and peer pressure susceptibility mediating the link between maternal behavior and adolescent risk behaviors.pdf
Published 2025“…Although parental influence decreases and peer influence increases during this time, parental behavior still plays a significant role. …”
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20215
Table 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.docx
Published 2025“…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …”
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20216
Video 2_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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20217
Growth and physiological response of Yulu <i>Hippophae rhamnoides</i> to drought stress and its omics analysis
Published 2024“…In T1 and T2, the differential genes were significantly enriched in the plant hormone signal transduction pathway, but there was no significant enrichment in the protein expression profile. …”
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20218
Image 3_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif
Published 2025“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
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20219
Image 3_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg
Published 2025“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”
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20220
Data Sheet 1_Gut microbiota is involved in the exacerbation of adrenal glucocorticoid steroidogenesis in diabetic animals by activation of the TLR4 pathway.pdf
Published 2025“…We observed morphological alterations as well as increased inflammation in the colon with a predominance of a Th17 cytokine profile in diabetic mice, in parallel to an increase in the epithelial-intestinal permeability and lipopolysaccharide content in the adrenals. TAK-242 significantly decreased the overexpression of adrenocorticotropic hormone receptor and 11β-hydroxysteroid dehydrogenase type 1 in the adrenal glands of diabetic mice. …”