Image 1_Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study.jpeg حسب Khalaf Kridin (7523390)

"…Introduction<p>Chronic, non-communicable inflammatory diseases (CIDs) affect a large portion of the population, imposing a significant morbidity, encompassing a substantial mortality. …"

Data Sheet 1_Case Report: A case of first-line treatment for rare ROS1 fusion mutation lung adenocarcinoma with entrectinib.pdf حسب Yifan Yang (170387)

"…Subsequently, the patient underwent whole-brain radiotherapy. Significant improvements were noted in her headache and insomnia symptoms. …"

Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... حسب Chase Garcia (21803576)

"…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"

Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx حسب Omar Z. Ameer (8900039)

"…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …"

Quantitative results on DRPD dataset. حسب Dunlu Lu (19964225)

"…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …"

Data Sheet 1_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.csv حسب Yanxian Gao (20555714)

"…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…"

Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx حسب Yuko Horikoshi (12202859)

"…In contrast, CAVI showed no significant correlation with blood pressure or body weight. …"

Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx حسب José Fidel Baizabal-Carvallo (11416508)

"…Cognitive impairment was a significant predictor of non-motor symptoms in their top three tiers [odds ratio [OR]: 3.88 (95% CI: 1.647 to 9.169)]. …"

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... حسب Hiroyuki Koami (3878434)

"…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …"

Data Sheet 1_Impact of artificial intelligence on electronic health record-related burnouts among healthcare professionals: systematic review.pdf حسب Berna Sarraf (21651629)

"…Nevertheless, EHR-related workload has been considered as a significant contributor to healthcare professionals’ burnout, a syndrome associated with emotional exhaustion, depersonalization, and reduced personal accomplishment. …"

Image 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

"…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"

Pathogenicity and transmissibility differences in goose-originated subgenotype 3 duck Tembusu virus in goose embryos and 3-day-old goslings حسب Ziqiao Zhao (18785775)

"…In the autumn of 2022, an outbreak of an infectious disease resembling DTMUV was reported in Guangdong Province, China, which caused significantly high mortality in goose embryos, and decreased egg production. …"

CLAD_sequence_files حسب Ryan Hunter (21714311)

"…Association with CLAD severity was driven by changes in phosphoethanolamine and phosphocholine lipids that increased and decreased, respectively, and metabolites from the bacterial pathogen <i>Pseudomonas aeruginosa</i>. …"

Table 1_Association between androgenetic alopecia and psychological well-being: a systematic review and meta-analysis.docx حسب Yuan Kong (110669)

"…However, no significant difference was observed in general distress (pooled SMD = -0.01, 95% CI [-0.39,0.37], p = 0.97). …"

Data Sheet 1_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip حسب Ziqi Tang (10904159)

"…With 0 and 15 μg/m³ taken as the reference concentrations, all-cause mortality decreased by 47.41% (233,173 cases) and 65.55% (240,448 cases), respectively. …"

Table1_GLYCINE betaine and seaweed-based biostimulants improved leaf water status and enhanced photosynthetic activity in sweet cherry trees.docx حسب Sílvia Afonso (20456483)

"…Biostimulants, especially EM, demonstrated a significant positive effect (p ≤ 0.001) on total phenolic content, with increases of approximately 25% to 50% in treated leaves. …"

Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx حسب Yang Yang (45629)

"…The overall lifestyle was observed as significant moderating role on the association between RNLEs and depressive symptoms (OR, 95%CI: 0.61 [0.40–0.95]).…"

LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p حسب Rouli Dai (17063211)

"…<p>Cerebral ischemia-reperfusion (CI/R) injury is a significant hurdle in ischemic stroke treatment. Substantial evidence indicates that long non-coding RNAs (lncRNAs) are implicated in CI/R injury. …"

Data Sheet 2_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip حسب Li Cui (37567)

"…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …"

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx حسب Jung Hoon Cha (19723588)

"…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…"