BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

“…This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …”

Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways by Ibraheem M. Attafi (14151735)

“…Treatment of rats with Pb for three consecutive days significantly increased the accumulation of Pb in lung tissues causing severe interstitial inflammation. …”

Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia by Taher, Ali

“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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Proteome analysis of Candida albicans cell wall mutants. (c2011) by Koussa, Joseph Wissam

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183-P by Khalaf, Roy A.

“…Conclusions: There was no statistically significant distribution of the different KIR genes between the cases (FMF patients) and controls (Lebanese population); however, an increase in the BB genotype was noted leading to an interesting future research question of whether or not KIR genotype is involved in the predisposition to or pathogenesis of FMF. …”
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Formation of Trihalomethanes during Seawater Chlorination by Ahmed Abdel-Wahab (1748986)

“…Rapid decrease of UV absorbance at 254 nm was also observed during seawater chlorination which is indicative of natural organic matter degradation into small organic molecules including THMs and other by-products. …”

Effect of acute and chronic grapefruit, orange and pineaple juice consumption upon blood lipoprotein synthesis and metabolism in the rat. (c2004) by Abou-Khalil, Jamil

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In vitro regulation of quorum sensing in Pseudomonas aeruginosa using synthetic autoinducers By Hrag Dilabazian A thesis by Dilabazian, Hrag

“…The inducing ability of OdDHL and BHL on the lasB gene was tested under different conditions: by increasing cell density or manipulating the concentration of or time of exposure to autoinducers, revealed that induction was not possible in elastase negative strains and had no detectable effect on the elastase positive strains. …”
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PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer by Reem Saleh (3513056)

“…Gene set enrichment analyses revealed that a significant number of these genes are related to the NF-kB, PI3K/Akt/mTOR, MAPK, and CD40 signaling pathways. …”

Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles by Muneer M. Ba-Abbad (14151660)

“…Overall, the results of this study showed that embedding a small amount of Co²⁺ ions doped ZnO NPs with PSf has significant potential to be applied in industrial-scale membrane applications.…”

A novel hybrid methodology for fault diagnosis of wind energy conversion systems by Khaled Dhibi (16891524)

“…Then, the sensitive and significant characteristics are transmitted to the RF model for classification purposes. …”

Past, present and future global mangrove primary productivity by Mark Chatting (5728340)

“…However, significant regional changes were identified, including substantial increases in NPP in the Southwest Australian Shelf (60.58 ± 97.9 %), the Warm Temperate Northeast Pacific (43.75 ± 65.7 %), and the Warm Temperate Northwest Pacific (31.55 ± 55.7 %), as well as decreases in <u>Southeast Asian </u>provinces like the Java Transitional (11.45 ± 6.2 %) and Western Coral Triangle (7.61 ± 9.6 %). …”

Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats by Ines Fki (14571855)

“…The hepatic immunohistochemical analysis revealed a significant increase in the expression of inflammatory genes (COX-2, NF-<em>κ</em>B, and TNF-<em>α</em>). …”

Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing by Mohamad Saad (214545)

“…Of 400 known genome-wide significant loci, 33 replicated at <i>P</i><10−4. However, the 9p21 locus did not replicate. …”

Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response by Noura Al-Zeheimi (5177066)

“…Unlike NRP-1, circulating PlGF was significantly increased (<i>p</i> = 0.014) in patients with a pathological complete response (pCR). …”

Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis by Ayman El-Menyar (440103)

“…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …”

Orofacial Clefts by El Baba, Nada

“…Through whole genome sequencing, we identified three variant genes, ARHGEF18, CUL7, and EPDR1, that we could link to the cleft phenotype. …”
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Comprehensive analysis of circulating miRNA expression profiles in insulin resistance and type 2 diabetes in Qatari population by Khaoula Errafii (10914446)

“…MiR-186 showed a consistent significant increase in insulin resistance subjects compared to NGT in the discovery and validation phase analysis. …”

p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-Cells by Idil I. Aigha (14913774)

“…Inhibition of p53 using pifithrin-μ (PFT-μ) at the MPC stage resulted in a significant increase in the number of PDX1+/NKX6.1+ cells and a reduction in the number of CHGA+/NKX6.1− cells. …”