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يعرض 1 - 20 نتائج من 699 نتيجة بحث عن '(( significant ((step decrease) OR (a decrease)) ) OR ( significant application against ))', وقت الاستعلام: 0.12s تنقيح النتائج
  1. 1

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications حسب Atefeh Esmaeili (462337)

    منشور في 2025
    "…<p dir="ltr">Fungal infections have emerged as a significant global health concern, with <i>Candida</i> species, opportunistic yeasts living symbiotically in various parts of the human body, playing a major role in pathogenic invasions. …"
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

    منشور في 2019
    "…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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    Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

    منشور في 2023
    "…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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    Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells حسب Queenie, Fernandes

    منشور في 2023
    "…Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. …"
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    Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells حسب Queenie Fernandes (14557388)

    منشور في 2023
    "…<p>Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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    Isolation and Evaluation of Qatari Rhizobacteria: Antagonistic Potential Against Phytopathogens and Growth Promotion in Tomato Plants حسب Amina BiBi (17679402)

    منشور في 2023
    "…The results indicated significant growth inhibition, reaching up to 50%. Subsequent in-vivo evaluations were conducted under greenhouse conditions, revealing that local strains exhibited significant growth-promoting effects. …"
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    Comparison between the American code ASCE7-16 and the Australian code AS1170.4 against the seismic design effects حسب AL-OBAIDI, ALI

    منشور في 2018
    "…The AS1170.4 used a tiered approach for the earthquake load starting from simple force to complicated displacement method. One of the significant advantages of this method especially on the low seismic zone is given the engineers to design against the vertical and wind loads then perform the displacement checking for the earthquake impact. …"
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