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decrease » increase (Expand Search)
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
Published 2019“…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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A systematic review of artificial intelligence applications for indoor air quality monitoring in educational settings
Published 2025“…The review identifies successful implementations of AI in educational settings, highlighting applications such as supervised and unsupervised learning for pollutant prediction, anomaly detection, and reinforcement learning (RL) for heating, ventilation, and air conditioning (HVAC) optimization. …”
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Application of Data Mining to Predict and Diagnose Diabetic Retinopathy
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Inverse Model Predictive Control for Power Electronic Converters
Published 2024“…The proposed IMPC technique is primarily based on the inverse of the conventional finite set model predictive control. The key advantage of this design is that it avoids predicting the controlled states for all possible switching-state vectors, while maintaining the advantage of adhering to multiple constraints and achieving multiple objectives. …”
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Comparison of four intensive care scores in prediction of outcome after Veno-Arterial ECMO: A single-center retrospective study
Published 2024“…APACHE-II > 27 (AUC of 0.66), calculated 24 h post-ICU admission after ECMO insertion, showed the greatest predictive ability for mortality. Multivariate logistic regression analysis of the four scores showed that APACHE-II > 27 and SOFA > 14, calculated 24 h post-ICU admission after ECMO insertion, were independently significantly predictive of mortality.…”
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Combining and adapting software quality predictive models by genetic algorithms
Published 2017“…The goal of quality models is to predict a quality factor starting from a set of direct measures. …”
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An ant colony optimization algorithm to improve software quality prediction models
Published 2011“…As a result, the prediction models built on one data set show a significant deterioration of their accuracy when they are used to classify new, unseen data. …”
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Development of Seed Variables Prediction Models for Use in Dynamic Backcalculation of FWD Data
Published 2022“…The selected seed-variables hold significant consequences on the-final backcalculated-results. …”
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