Intracutaneous ALA photodynamic therapy by Tannous, Zeina

“…Low doses (≤0.016%) targeted fat; producing fat necrosis with minimal inflammation, manifested both clinically and histologically. …”
Get full text
Get full text
Get full text
Get full text

Extent and Mitigation of Financial Toxicity of Immune Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma by Nabil E. Omar (9545756)

“…This challenge is particularly severe in LMICs, where the high incidence of HCC is compounded by the unaffordability of effective treatments, creating a significant barrier to care. …”

Trans-resveratrol-loaded nanostructured lipid carrier formulations for pulmonary drug delivery using medical nebulizers by Iftikhar, Khan

“…Moreover, the air jet nebulizer exhibited significantly higher emitted dose (ED) (87.44 ± 3.36%), fine particle dose (FPD) (1652.52 ± 9.68 µg) fine particle fraction (FPF) (36.25 ± 4.26%), and respirable fraction (RF) (93.41 ± 4.03%) when the F1 formulation was used as compared to the F2 formulation. …”
Get full text
Get full text
Get full text

Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Abbas, Tariq

“…Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …”
Get full text
Get full text
Get full text

Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses by Merilyn Lock (9440240)

“…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …”

Olodaterol for the treatment of chronic obstructive pulmonary disease by Ramadan, Wijdan H.

“…Other clinical trials demonstrated that olodaterol produced beneficial effects on FEV1 measures throughout the 24-hour dosing interval. …”
Get full text
Get full text
Get full text
Get full text

Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor–induced hepatotoxicity is mediated by Kupffer cells by Abi-Habib, Ralph J.

“…DT388GMCSF, a fusion toxin composed of the NH2-terminal region of diphtheria toxin (DT) fused to human granulocyte-macrophage colony-stimulating factor (GMCSF) has shown efficacy in the treatment of acute myeloid leukemia. However, the primary dose-limiting side effect is liver toxicity. We have reproduced liver toxicity in rats using the rodent cell-tropic DT-murine GMCSF (DT390mGMCSF). …”
Get full text
Get full text

Activation of K_v7 channels with the anticonvulsant retigabine alleviates neuropathic pain behaviour in the streptozotocin rat model of diabetic neuropathy_v7 c... by Laiche Djouhri (112613)

“…Retigabine given at a dose of 15 mg/kg (but not at 7.5 mg/kg, i.p.) significantly attenuated mechanical, but not heat hypersensitivity in DPNP rats, and was as effective as the positive control gabapentin. …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…In conjunction with these data, whole-cell electrophysiological studies revealed that this concentration had maximum effect on membrane potentials, conductance and currents. …”

Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine by Hamda A. Al-Naemi (14151675)

“…The aim of the study was to evaluate the effect of chronic low-dose Cd on vascular structure and function. …”

Trends of acetaminophen overuse among ambulatory patients in Lebanon by Ramadan, Wijdan H.

“…Acetaminophen (APAP), also known as paracetamol, is used by millions of people worldwide for its antipyretic and analgesic properties. At therapeutic doses, APAP is effective and safe. However, the long-term use and the ingestion of inappropriately high doses pose substantial risks to APAP users. …”
Get full text
Get full text
Get full text

Alpelisib Therapy in 2 Patients With Congenital Hyperinsulinism by Khalid Alburshad (22467244)

“…This allowed for the tapering and discontinuation of other medications (diazoxide and octreotide) and facilitated a transition to bolus gastrostomy-tube/oral feeding. No significant adverse effects were reported. Alpelisib shows promise as both an adjunctive and primary therapy for CHI, improving glucose levels and reducing dependence on continuous feeding and other medications. …”

Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis by Osama Hussein (21301202)

“…In ACG patients, the pooled effect showed a percentage of IOP reduction (IOPR%) of 35.22% with a mean IOP reduction of −9.51 mmHg, <i>p</i>< 0.001 at 12 months, and an IOPR% of 27.47% with a mean reduction of −6.37 mmHg, <i>p</i> < 0.001 at 24 months. …”

Differential water quality in confined and free-flowing water bodies, Lebanon by Korfali, Samira Ibrahim

“…Statistical analysis of the data revealed significant differences in water quality. The differences could be attributed to the fact that whereas the Qaraaoun reservoir is receiving domestic waste discharges that lead to an increase in the CO2 content and a pH decrease, the Nahr-Ibrahim River is influenced by agricultural runoffs and industrial discharges that increase the pH values. …”
Get full text
Get full text
Get full text

Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States by Yahya, Fares

“…BRMUS factors, such as fatigue, depression, and anger, significantly decrease in the enhancement group compared to vigilance group. …”
Get full text

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. …”
Get full text
Get full text
Get full text

Smart Synthesis of Trimethyl Ethoxysilane (TMS) Functionalized Core–Shell Magnetic Nanosorbents Fe₃O₄@SiO₂: Process Optimization and Application fo... by Khalid Al-Saad (5768084)

“…Pareto chart of standardized effects together with analysis of variance (ANOVA) at 95.0 confidence interval (CI) were used to determine statistically significant variable(s). …”

Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

“…Development of new, effective therapies for metastatic melanoma that target novel pathways associated with the genesis of metastatic disease is a major unmet clinical need. …”
Get full text
Get full text
Get full text

Examining depression, antidepressants use, and class and their potential associations with osteoporosis and fractures in adult women: Results from ten NHANES cohorts by Humam Emad Rajha (22225114)

“…<h3>Introduction</h3><p dir="ltr">Osteoporosis, a significant public health concern, affects millions of adult women globally, leading to increased morbidity and fracture risk. …”

Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting by Ananth Nazarene (21239912)

“…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …”