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281
Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients
Published 2019“…We also investigated correlations between the levels of different CD4<sup>+</sup> T cell subsets and the clinicopathologic features including disease stage and tumor budding. We found a significant increase in the levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> T cells, which represent potentially highly immunosuppressive Tregs, in the CRC TME. …”
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282
Analysis of Diabetes Apps to Assess Privacy-Related Permissions: Systematic Search of Apps
Published 2021“…Accordingly, the availability of mobile apps for diabetes has been steadily increasing. Most of the previous reviews of diabetes apps have focused on the apps’ features and their alignment with clinical guidelines. …”
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283
Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
Published 2018“…The outcome of these events, abundant regional solar irradiation and drop in global PV prices has led to the significant developments and innovations in the solar energy sector. …”
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284
Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study
Published 2023“…Moreover, homozygous variants were found in 7 families (25.9%), with a sixfold increase in homozygous burden in consanguineous versus non-consanguineous families (13.6% and 1.8%, respectively). …”
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285
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”
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286
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”
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287
Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy
Published 2024“…HPV and EBV are known to be increasingly involved in the pathogenesis of various classes of cancers like cervical, head and neck, colorectal, breast, oral and anogenitial. …”
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288
Occupational Violence at Lebanese Emergency Departments
Published 2011“…Exposure to verbal abuse was associated with serious outcomes including significantly higher levels of occupational burnout and an increased likelihood to quit current job. …”
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289
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
Published 2022“…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …”
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290
The lung protein that tells all
Published 2016“…</p><p dir="ltr">Serum SP-D levels were significantly increased in all patients with COPD compared to the healthy cohort. …”
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291
The advent of the ‘social moment of truth’ in online communities
Published 2017“…Concurrently, retailers have significantly increased their social presence to influence shoppers’ buying decisions. …”
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292
Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy
Published 2024“…HPV and EBV are known to be increasingly involved in the pathogenesis of various classes of cancers like cervical, head and neck, colorectal, breast, oral and anogenitial. …”
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293
Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients
Published 2018“…Although molecular and cellular determinants involved in the onset and progression of this devastating disease are largely unknown, an aberrant remodeling of the pulmonary vasculature appears to have implications in IPF pathogenesis. …”
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294
Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
Published 2023“…Patient satisfaction from the provided interventions/services was determined by means of an overall rating. The correlation between practiced roles and patient satisfaction with received interventions/services was determined.…”
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295
Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy
Published 2021“…Silencing LDHC in four breast cancer cell lines significantly increased the presence of giant cells, nuclear aberrations, DNA damage, and apoptosis. …”
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296
Lifetime prevalence, risk, and treatment of mood and anxiety disorders in Qatar's national mental health study
Published 2024“…Treatment is significantly delayed and delivered largely in non‐healthcare sectors thus the need for increased literacy of mental illness to reduce stigma and improve earlier help‐seeking in healthcare settings.…”
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297
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase
Published 2022“…Expression of cancer stem cell markers (CD133, CD44, ganglioside GD2) was significantly increased in A375 spheres, as detected by flow cytometry. …”
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298
Malware detection for mobile computing using secure and privacy-preserving machine learning approaches: A comprehensive survey
Published 2024“…The accuracy of these models largely depends on the size and quality of the training dataset. …”
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299
Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
Published 2019“…Treatment with a combination of 2DG (5 mM) and metformin (2 mM) also significantly decreased cell proliferation, migration and tubulogenic capacity when compared to cells that were treated with either 2DG or metformin alone. …”