يعرض 1,621 - 1,640 نتائج من 12,928 نتيجة بحث عن '(( significant ((step decrease) OR (teer decrease)) ) OR ( significantly increased decrease ))', وقت الاستعلام: 0.60s تنقيح النتائج
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    Presentation 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.pptx حسب Juan Chen (61123)

    منشور في 2025
    "…</p>Conclusion<p>This study integrated meta-analysis, murine model validation, and single-cell transcriptomic profiling to demonstrate a significant reduction of BDNF in CKD. Furthermore, renal BDNF expression decreased locally, predominantly originating from proximal tubule cells, macrophages, and podocytes, possibly epigenetically inhibited by the upregulation of lnc RNA Bdnf-as.…"