Data Sheet 1_Global burden of disease among adolescents and young adults with drug use disorders, 1990–2021: based on GBD 2021.doc حسب Ming Wang (172316)

"…Additionally, gender plays a significant role in the distribution of this burden, with males experiencing a higher burden than females. …"

Data Sheet 2_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf حسب Diana Maltseva (11678641)

"…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …"

Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip حسب Xueshan Chen (17477633)

"…Further transcriptome analysis demonstrated that PGL exerted significant transcriptional changes to bacteria. Enrichment analysis showed PGL could inhibit growth of P. aeruginosa and E. coli by repressing the biosynthesis of secondary metabolites.…"

Table 4_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

"…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"

Image 1_iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis.tif حسب Jingyu Zhao (2371618)

"…Background<p>Cryptococcal meningitis (CM) is a significant global health issue, particularly affecting individuals with HIV. …"

Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx حسب Qingguo Liu (9620123)

"…From 1990 to 2021, the absolute number of stroke-related DALYs attributable to metabolic-risks increased by 22.23%, while the ASDR decreased by 0.78% annually. Regional disparities were evident, with East Asia reporting the largest number of stroke-DALYs attributable to metabolic-risks and Southeast Asia exhibiting the highest ASDR. …"

Table 6_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

"…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"

Evaluation results. حسب Briya Tariq (19666901)

"…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …"

Data Sheet 1_Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway.csv حسب Jiejie Hu (6190622)

"…Spearman’s correlation analysis revealed a significant correlation between the hub genes and ferroptosis-related DEGs. …"

Table 1_Associations of urinary enterolignans and risk of overall and cause-specific mortality with or without serum albumin adjustment: a prospective cohort study.docx حسب Zisuo Sun (22310437)

"…Meanwhile, urinary ENL concentrations were associated with decreased all-cause mortality risk (HR = 0.74, 95% CI: 0.59–0.93, P_trend = 0.020) only in the group with higher HSA levels.…"

Table 6_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx حسب Lin-Feng Wang (10944843)

"…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …"

Data Sheet 1_In silico molecular studies of Phosphinogold(I) thiocarbohydrate complexes: insights into multi-target anticancer mechanisms.docx حسب Alkhair Adam Khalil Mohamed (21529289)

"…While acetylation decreased binding affinity; it enhanced cellular activity as reported in in vitro studies indicative of the need to balance lipophilicity and binding strength in future ligand design.…"

Image 4_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff حسب Zilun Wu (18696883)

"…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …"

Data Sheet 1_CD19+ B cell depletion: a novel strategy to alleviate ischemic stroke damage.pdf حسب Yu Xu (52257)

"…Mice subjected to middle cerebral artery occlusion (MCAO) exhibited significant reductions in infarct size and brain edema, prolonged post-MCAO survival, and improved behavioral outcomes following aCD19 Ab treatment. …"

Supplementary Material for: Angiopausin® and Angiopoietin: Unveiling New Mechanisms in Rosacea Treatment through Kinetic Erythema Analysis with the AAREA® Algorithm حسب figshare admin karger (2628495)

"…Reductions in total IEA scores were observed at week 4 (W4; p<0.05) and through W8 to W64 (p<0.001). Decreases in individual scores were also observed for flushing, NTE and edema (W4 to W64: p<0.001), and telangiectasia (W8 to W32; p<0.001). …"

Supplementary file 1_Proof-of-concept of a prior validated LC-MS/MS method for detection of N-lactoyl-phenylalanine in dried blood spots before, during and after a performance diag... حسب H. Bauhaus (22335913)

"…No statistically significant correlations were identified between lac-phe and lactate, glucose as well as anthropometric and respiratory parameters.…"

Table 2_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx حسب Rui Jiang (264894)

"…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …"

Table_1_Oxidative stress and inflammation mediate the association between elevated oxidative balance scores and improved sleep quality: evidence from NHANES.docx حسب Qu Zhang (486455)

"…Sensitivity analyses revealed a significant association between OBS and sleep disorder (p < 0.001).…"

Table 1_Probabilistic human health risk assessment of commercially supplied jar water in Gopalganj municipal area, Bangladesh.docx حسب Partha Pratim Brahma (19696279)

"…<p>Every day, the amount of quality fresh water decreases notably due to contamination of drinking water. …"

Image 2_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair... حسب Ulrike Gimsa (9730208)

"…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …"