Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

Behavioral characterization of prenatal nicotine exposure (PNE) and control mice. by Rodrigo Vidal (4177060)

“…Quantification of the average total distance traveled. Significant differences were observed between PNE animals and control mice (PNE: 78.37 ± 2.01 m; n = 6; Control = 51.57 ± 3.33 m; n = 6), t = 6,883 df = 10, p < 0,0001. …”

The effect of inulin treatment on plasma untargeted metabolomic profiles in mice of diverse groups. by Ke Li (106849)

“…Color key in the heat map represents the metabolite expression value: red represents the significant increases and blue stands for the remarkable decreases. …”

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Cilium disassembly defects were rescued with ectopic expression of CCDC66 but not CEP104. by Jovana Deretic (13113617)

“…Mean cilia length measured in 3D in CCDC66 depletion is decreased to 0.97-fold of the mean control length. …”

Additional file 6 of NSDHL contributes to breast cancer stem-like cell maintenance and tumor-initiating capacity through TGF-β/Smad signaling pathway in MCF-7 tumor spheroid by So-Hyun Yoon (5353250)

“…Supplementary Material 6: Figure S6. A-83-01 (50 µM) decreased the phosphorylation of both SMAD2 and SMAD3 but did not show significant toxicity in MCF-7-spheroids. …”

Disturbances in drylands: Interactions among herbivory, drought, and termite activity in savanna plant communities by Harry Wells (11430190)

“…We used 15 years of a 28-year experiment spanning several significant droughts to investigate how rainfall, large herbivores, and soil-engineering termites affect understory vegetation in a semi-arid savanna. …”

<i>ADH7, FABP5, ALDH1A1, CRABP-2, PPARγ</i> and <i>VEGFA</i> mRNA and ADH7, FABP5, CRABP-2, PPARγ and VEGFA protein levels in limbal stromal cells (LSCs) and aniridia limbal stroma... by Shuailin Li (11907158)

“…Furthermore, 0.078 and 0.313 μg/mL travoprost treatment significantly decreased ADH7 protein levels in LSCs (p = 0.039; p < 0.001) and 0.313 μg/mL travoprost treatment significantly increased ADH7 protein levels in AN-LSCs, compared to their untreated controls (p = 0.039) <b>(B, C)</b>. …”

Treating sleep disturbances in refugees and asylum seekers: results from a randomized controlled pilot trial evaluating the STARS group intervention by Britta Dumser (20698169)

“…However, there was no significant interaction with condition at post-treatment for the primary outcome (<i>d</i> = 0.29) and most secondary outcomes; the only exceptions were increased coping with nightmares, decreased daytime sleep, and time in bed.…”

Table_1_Estimation of scrub typhus incidence and spatiotemporal multicomponent characteristics from 2016 to 2023 in Zhejiang Province, China.XLSX by Haocheng Wu (559031)

“…However, there may be significant bias in the number of reported cases of scrub typhus, to the extent that its epidemiological patterns are not clearly understood. …”

Table_1_Association between phthalates exposure and non-alcoholic fatty liver disease under different diagnostic criteria: a cross-sectional study based on NHANES 2017 to 2018.pdf by Jiazhen Zou (19739203)

“…Due to changes in legislation, the use of traditional phthalates has gradually decreased, and the phthalates substitutes is getting more attention. …”

Data Sheet 1_Standardized Rhodiola rosea injection for left ventricular remodeling and inflammation in patients with HFrEF: a systematic review and meta-analysis.docx by Xuqin Du (8803772)

“…</p>Results<p>Twenty-five RCTs with 2,325 participants were included. SRRI significantly improved LVR, indicated by increased LVEF (MD = 6.81, 95% CI: 5.71 to 7.91, P < 0.00001), reduced LVEDD (MD = −4.37, 95% CI: −5.42 to −3.33, P < 0.00001), and decreased LVESD (MD = −4.48, 95% CI: −5.42 to −3.58, P < 0.00001). …”

Data Sheet 1_Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study.docx by Heinz Wiendl (237353)

“…IgG and IgM levels remained above the lower limits of normal in most participants. sNfL levels decreased, remaining reduced by M24. Significant reductions in the annualized combined unique active lesion count occurred from M2 onwards. …”

Data Sheet 2_Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study.csv by Heinz Wiendl (237353)

“…IgG and IgM levels remained above the lower limits of normal in most participants. sNfL levels decreased, remaining reduced by M24. Significant reductions in the annualized combined unique active lesion count occurred from M2 onwards. …”

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. by Weiran Huang (8934899)

“…Within 6 hours, the difference was highly significant with a p-value < 0.0001. Later, at 7–9 hours, the OHT groups continued to show significant differences compared to controls, with a p-value of 0.0004. …”