Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer حسب Ahmed, Amal Elsadig Elamir

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Deep Learning for the Accurate Prediction of Triggered Drug Delivery حسب Husseini, Ghaleb

"…The deep learning-based predictions significantly outperform linear predictions, proving the utility of advanced computational methods in drug delivery. …"
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The Effect of Ultrasound on the Drug Delivery of RGD-Targeted Liposomes حسب Mahmoud, Mohamad

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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

"…Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…RNA-sequencing analysis further validated the findings by showing a significant increase in genes associated with lipid metabolism, bile acid secretion, and suggested the activation of hepatic stellate cells and hepatic fibrosis in MH lacking FOXA2. …"

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"

Dissecting the signaling pathways regulating the vascular endothelial growth factor (VEGF) in brain tumor cells. (c2017) حسب Nicolas, Samer Michel

"…However, when both RhoA and RhoC were knocked down, VEGF expression decreased after EGF stimulation. Moreover, when the astrocytoma cells were subjected to hypoxia at different times, we detected a significant increase in pERK. …"
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Orofacial Clefts حسب El Baba, Nada

"…We also found an increased RhoA activation in these cells which could be causative of the observed increase in focal adhesions as well as a decreased Cdc42 activation which could further explain the loss in cell polarity. …"
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Hepatoprotective, Antioxidant, and Anticancer Effects of the Tragopogon porrifolius Methanolic Extract حسب Tenkerian, Clara

"…In rats subjected to CCl4-induced hepatotoxicity, significant increase in CAT, SOD, and GST levels was detected. …"
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The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France حسب Harakeh, Mostafa

"…Accordingly, we find that, following IFRS adoption, earnings management activities decrease among high-divergence firms prior to issuing SEOs. …"
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer حسب El Mais, Nour

"…HuArgI (Co)-PEG5000 is a potential drug to target cancers that depend on exogenous sources of arginine and cannot synthesize their own. In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …"
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …"
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Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications حسب Fang Yu (156838)

"…They do, however, develop cardiovascular complications, including hypertension and tachycardia, which we show are due to increased sympathetic autonomic nervous system activity and not cardiac or vascular smooth muscle autonomous defects. …"

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema حسب Diab, Khalil J.

"…Measurements and Main Results: Consistent with previously reported de novo activation of ceramide synthesis, VEGFR inhibition triggered increases in lung ceramides, dihydroceramides, and dihydrosphingosine, but did not alter sphingosine kinase activity or S1P levels. …"
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Walking around the preferred speed: examination of metabolic, perceptual, spatiotemporal and stability parameters حسب Lina Majed (7485380)

"…While metabolic, perceptual and spatiotemporal values were sensitive to the smallest change in speed (i.e., 0.5 km·h⁻¹⁾, a significant increase in the rate of carbohydrate oxidation and decrease in % fat oxidation were only observed at speeds above PWS. …"

Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development حسب Al Saneh, Mounir

"…Our results showed that there is no difference in viability of the VWS patient cells compared to healthy control cells. However, a significant decrease in the migratory and adhesion ability of the VWS patient cells was detected compared to the control, which could account for the phenotype. …"
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Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway حسب Shilpa Kuttikrishnan (3520079)

"…NSP‐B demonstrated significant growth inhibition and apoptotic induction, triggered by reduced AKT activation and downregulation of the inhibitors of apoptotic proteins and S‐phase kinase protein. …"

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro حسب Najem, Sonia A.

"…Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study حسب Almu'atasim Khamees (11875640)

"…Females who started smoking last year were 2.6‐fold more than males (<i>p</i>< 0.0001). We also noticed that there is a significant relationship between those who started smoking and are <18 years, living in a family consisting of seven members or more, being unemployed, having a diploma or bachelor's degree in a health‐related major, having no chronic illnesses, increasing of daily meals or night meals, almost daily sugar intake, starting to follow social media account concerning physical activity, exercising once or twice a week, and sleeping more hours per day since the beginning of the pandemic (<i>p</i> < 0.01).…"

Cooperative Learning and Second Language Acquisition: Learner Empowerment in the UAE حسب Iyer, Rekha Venkatraman

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