Image 4_A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity.jpg by Dan Qin (663961)

“…However, due to their complexity, these drugs have a higher potential to be immunogenic, leading to the generation of anti-drug antibodies (ADAs). Clinically significant ADAs have an impact on pharmacokinetics (PK), pharmacodynamics (PD), effectiveness, and/or safety. …”

Image 2_A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity.jpg by Dan Qin (663961)

“…However, due to their complexity, these drugs have a higher potential to be immunogenic, leading to the generation of anti-drug antibodies (ADAs). Clinically significant ADAs have an impact on pharmacokinetics (PK), pharmacodynamics (PD), effectiveness, and/or safety. …”

Anti-SARS-CoV-2 antibody level comparison based on subject characteristics. by Andhika Rachman (7827761)

Photomicrographs of prostate sections immunostained with anti-caspase 3, anti-TNF-α, and anti-PCNA antibodies (Magnification × 400). by Rabab Ahmed Rasheed (12536918)

Anti-Spike and Neutralization Abs before and after the booster shots in vaccinated individuals. by Sana Eybpoosh (2826068)

Heterogeneity in the Relationship between Anti-Bullying Laws (ABLs) and Bullying Behavior by External Environment Characteristics, Linear Probability Model. by Mona Ahmadiani (22320409)

Tumor growth increases the frequency and number of regulatory T cells in the spleen of obese mice without affecting their phenotype. by Aleida Núñez-Ruiz (12463062)

Subjects:

Genes with significantly changed expression in Δ<i>fruR</i> strain. by Hossam Abdelhamed (419443)

Subjects:

Additional challenge with CD99 leads to increased autoantibody levels. by Henrika Jodeleit (4722312)

PD-1 deficiency does not significantly impact the pathogen load and pathology following <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

Subjects:

Different effects of intervention: We simulate an intervention that decreases the nosocomial transmission rate by a factor of 70% (<i>β</i>→0.3<i>β</i>) starting from January 2011.... by Tal T. Robin (17847380)

Anti-TRPA1 antibody validation using immunofluorescence labeling in mouse DRGs. by Alison Xiaoqiao Xie (6196883)

The increasing virus particle binding affinity of the bivalent form compared to monovalent single-domain V_L. by Phuong Thi Hoang (13549906)

Subjects:

FXIII inhibitory titers and anti-FXIII autoantibody levels in various variants. by Tsukasa Osaki (1491454)

DataSheet_1_Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased protective efficacy.pdf by Natasha KC (10954771)

Shows the 5′ region and the exons of the <i>C3</i> gene in the vertical line and the three new SNPs that we found by sequencing. by Yonghui Wang (287491)

Manhattan plot that shows the location of genes involved in folate, homocysteine, and transsulfuration pathways for which we observed, from hybrid analyses, a significantly decreased risk of obstructive heart defects when the risk variant was paternally-derived compared to maternally-derived, The National Birth Defects Prevention Study, USA, October 1997–August 2008 births. by Jenil Patel (10271373)

“…<p>Manhattan plot that shows the location of genes involved in folate, homocysteine, and transsulfuration pathways for which we observed, from hybrid analyses, a significantly decreased risk of obstructive heart defects when the risk variant was paternally-derived compared to maternally-derived, The National Birth Defects Prevention Study, USA, October 1997–August 2008 births.…”

Human mesenchymal stem/stromal cells (hMSCs) increased levels of alternatively activated macrophages (AAM) and anti-inflammatory cytokines. by Kazumichi Yagura (4537504)

“…Transplantation of hMSCs significantly increased the expression of the AAM markers <i>Arg1</i> <b>(D)</b> and <i>Chil3</i> <b>(E)</b>, as well as that of the anti-inflammatory cytokine <i>IL-4</i> <b>(F)</b> on pod 14. …”

Changes in alpha diversity in the weeks before anti-TNF-a treatment. by Katrine Carlsen (5477300)

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells by Pau Muñoz-Guardiola (9282482)

“…Importantly, we have optimized a method to quantify mRNAs in blood samples from patients enrolled in the ongoing clinical trial, who showed significant increased <i>DDIT3</i> and <i>TRIB3</i> mRNAs. …”