Azole drugs have differential efficacy in varied models of immunosuppression in larval zebrafish hosts by Kevin E. Ayala (21979064)

“…<p>Fungal infections are an increasing cause of mortality in immunosuppressed human patients, and antifungal drug treatments are still ineffective in a significant percentage of cases. A gap in our understanding of antifungal drug treatment is whether different drugs have differential efficacy in hosts that are experiencing different forms of immunosuppression.…”

Table 1_The efficacy and safety of danuglipron and orforglipron in patients with type 2 diabetes and obesity: a systematic review and meta-analysis.docx by Jingjing Zhou (179820)

“…Meta-analysis results demonstrated that danuglipron significantly decreased HbA1c (mean difference [MD]: −0.90; 95% CI: −1.06, −0.74), FPG (MD: −24.66; 95% CI: −30.45, −18.86) and weight (MD: −2.17; 95% CI: −3.10, −1.23) and improved FPI (MD: 2.94; 95% CI: 1.50, 4.38). …”

Table1_Prediction of the potentially suitable areas of Eucommia ulmoides Oliver in China under climate change based on optimized Biomod2 and MaxEnt models.doc by Guoqiong Cao (20220729)

“…<p>Eucommia ulmoides Oliver is a medicinal plant of significant economic importance. Its cortex has been employed for centuries to alleviate various conditions such as lumbar pain, knee pain, and osteoporosis. …”

Presentation 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.pptx by Hui Li (32376)

“…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …”

Data Sheet 1_Synergistic effects of Candida albicans and Porphyromonas gingivalis biofilms on epithelial barrier function in a 3D aspiration pneumonia model.pdf by Ewelina Wronowska (20555480)

“…Introduction<p>Polymicrobial infections involving Candida albicans and Porphyromonas gingivalis represent a significant challenge in maintaining epithelial barrier integrity. …”

Table 4_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx by Nirmal Parajuli (751983)

“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”

Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx by Ji Yang (114503)

“…Background<p>Current therapeutic options for inflammatory bowel disease (IBD) remain suboptimal due to limited efficacy, significant side effects, and high relapse rates, necessitating novel treatment strategies. …”

Image4_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula... by Huipeng Fang (12587509)

“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”

Data Sheet 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.xlsx by Jiaxuan Liu (5185280)

“…</p>Results<p>SHTX treatment significantly altered the gut microbiota composition in T2DM rats, increasing the relative abundance of Bacteroidetes while decreasing that of Firmicutes, which was closely correlated with improved insulin sensitivity. …”

Table1_Myocardial infarction in rats was alleviated by MSCs derived from the maternal segment of the human umbilical cord.DOCX by Shuifen Sun (19855329)

“…In rats with MI, maternal-MSCs significantly restored cardiac contractile function and reduced the infarct size. …”

Table 1_The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis... by Yuchan Zhong (22518395)

“…The results showed that antioxidant supplementation significantly alleviated pelvic pain (continuous outcomes: SMD = −2.68; p < 0.00001; binary outcomes: RR = 9.31; p < 0.0001), dysmenorrhea (SMD = −1.77; p = 0.01; RR = 2.39; p = 0.03), and dyspareunia (SMD = −2.33; p = 0.01; RR = 5.40; p = 0.003), and significantly decreased peripheral blood malondialdehyde (MDA) levels (SMD = −7.58; p = 0.001). …”

Presentation 1_Unveiling the gut-heart potential connection: microbiota’s role in kawasaki disease and coronary artery lesions.zip by Qing Yang (67856)

“…Thirteen genera showed statistically significant changes, including Enterococcus, Bacteroides, Faecalibacterium, Agathobacter, Lachnospiraceae_NK4A136_group, Roseburia, Monoglobus, etc. …”

Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Image11_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellul... by Huipeng Fang (12587509)

“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”

Data Sheet 1_Featured intestinal microbiota associated with hepatocellular carcinoma in various liver disease states.pdf by Xiu Sun (8539698)

“…In the CHB-HCC, CC-HCC, and DC-HCC groups, the abundance of Bacteroides, Prevotella, and Faecalibacterium gradually decreased, whereas Klebsiella, Haemophilus, and Streptococcus increased. …”

Image4_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

Data Sheet 1_The TFRC as a prognostic biomarker and potential therapeutic target in cervical cancer: a preliminary study.docx by Jing Wang (6206297)

“…</p>Conclusions<p>TFRC exhibits significant diagnostic and prognostic value in cervical cancer.…”

Table 5_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx by Nirmal Parajuli (751983)

“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”

Data Sheet 1_Antibiofilm potential of plant extracts: inhibiting oral microorganisms and Streptococcus mutans.pdf by Nomi Bartels (20997935)

“…P. cretica was able to inhibit and kill S. mutans at a concentration of 0.6 mg/ml, but its effectiveness in biofilm inhibition significantly decreased at 2.5 mg/ml.</p>Discussion<p>The study's hypothesis that all extracts would exhibit an antimicrobial effect was thus confirmed.…”

raw data by Boya Gao (21686150)

“…Bacterial abundance under moderate and extreme disturbances was significantly lower than that in the control, whereas fungal abundance was significantly higher under extreme disturbance. …”