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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
time increased » rate increased (Expand Search), use increased (Expand Search)
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19541
Short-Ranged United-Atom Model for Efficient Simulations of Glycerol and Its Aqueous Mixtures
Published 2025“…While AA simulations are widely used, they overestimate the α-conformation and incur significant computational costs. Coarse-grained (CG) models provide an efficient alternative but have yet to accurately describe glycerol’s conformational distribution and thermodynamic behavior. …”
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19542
Data Sheet 1_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.pdf
Published 2025“…Additionally, we identified an increase in the ARGORNPROST-PWY pathway (L-arginine degradation, q = 0.003) and a decrease in the PWY-6478 pathway (GDP-D-glycero-α-D-manno-heptose biosynthesis, q = 0.015) in MSA patients compared with HCs.…”
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19543
Table 5_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx
Published 2025“…</p>Results<p>While higher methionine intake reduced hemoglobin levels, no other significant changes in the immune status were observed. …”
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19544
Image_3_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.tif
Published 2025“…The diet containing L. acidophilus at 1 × 10<sup>7</sup> CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”
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19545
Table 3_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.xlsx
Published 2025“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”
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19546
Datasheet2_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi...
Published 2024“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”
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19547
Datasheet1_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi...
Published 2024“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”
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19548
Data Sheet 1_Characterization and immunoprotection of thioredoxin reductase TrxB knockout mutant of Salmonella Enteritidis.pdf
Published 2025“…We also observed a significant decrease in the expression of virulence-related genes in the trxB-knockout mutant. …”
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19549
Table 1_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.docx
Published 2025“…</p>Results<p>While higher methionine intake reduced hemoglobin levels, no other significant changes in the immune status were observed. …”
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19550
Image1_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.tif
Published 2024“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”
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19551
Table 2_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.xlsx
Published 2025“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”
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19552
Immune cell subsets and cytokine levels in peripheral blood between healthy donors and triple-negative breast cancer (TNBC) patients and in patients before and after the first phas...
Published 2025“…This study showed an increase in the percentage of CD14<sup>+</sup> monocytes and CD56<sup>high</sup> NK cells and a decrease in CD19<sup>+</sup> B-cells after first-phase chemotherapy, while no significant differences in cell percentages were seen between healthy donors and treatment-naïve patient groups. …”
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19553
Immunogenicity persistence after four intramuscular triple-dose or standard-dose hepatitis B vaccine in patients receiving methadone maintenance treatment: A 1-year follow-up study...
Published 2025“…No significant differences were observed in the persistence of vaccine-induced responses among the three groups (<i>p</i> = .204). …”
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19554
Table_2_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.doc
Published 2025“…The diet containing L. acidophilus at 1 × 10<sup>7</sup> CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”
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19555
Data Sheet 1_Effect of purpose-directed acupuncture on the pharyngeal phase in stroke patients with dysphagia based on surface electromyography: a randomized controlled trial.pdf
Published 2025“…Compared to the control group, the treatment group showed a significant increase in FOIS scores and a decrease in SSA scores. …”
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19556
Table 1_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.xlsx
Published 2025“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”
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19557
Data Sheet 1_Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function.docx
Published 2025“…</p>Results<p>Prostaglandin E2 (PGE2) stimulation of retinal endothelial monolayers caused a decrease in barrier permeability in electric cell-substrate impedance sensing (ECIS) assays and dextran flux assays. …”
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19558
Table4_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.docx
Published 2024“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”
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19559
Bioactive peptide PDBSN improves mitochondrial function and suppresses oxidative stress in human adipose cells
Published 2025“…Results show that PDBSN significantly increased MMP while decreasing TG and ROS levels. …”
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19560
Supplementary file 1_Emergency department overcrowding: first Swiss application of the Emergency Department Work Index and risk factors for overcrowding.pdf
Published 2025“…Introduction<p>Emergency department (ED) overcrowding is associated with increased waiting time, reduced patient satisfaction, and decreased quality of care. …”