Table 2_Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021.docx حسب Yue Li (102191)

"…Compared with 1990, although the ASIR and age-standardized disability-adjusted life years rate (ASDALYsR) decreased, absolute numbers increased significantly. …"

Data Sheet 2_Effects of therapeutic horsemanship on caregiver stress scores of children with autism.pdf حسب Danielle C. Barron (21634196)

"…</p>Results<p>We observed caregivers experienced a statistically significant decrease (p=0.03) in their stress levels over a single semester of TH participation demonstrated by a reduction in DASS-21 stress subcategory (pre intervention mean 12.77 (SD = 9.95), post-intervention mean 8.62 (SD = 10.98). …"

Model parameters. حسب Yanxu Liang (22227024)

"…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…"

Image 4_Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials... حسب Virginie Piffaut (22399978)

"…</p>Results<p>While ascorbic acid did not exhibit any efficacy versus its vehicle in limiting skin hyperpigmentation induced by HEV, the use of 2-MNG (0.5 or 1%) led to an early significant decrease in HEV-induced pigmentation, which was sustained until the end of the study, as evidenced by colorimetry and significantly scored by visual assessment. …"

DataSheet1_OsPDIL1-5: dual role in promoting growth and development while modulating drought stress tolerance in rice (Oryza sativa L.).docx حسب Jilin Chen (19847928)

"…This discovery highlights the importance of GDDT as a pleiotropic gene with significant implications for both plant growth and drought resistance. …"

Supplementary information files for "Incorporating fluid-structure interactions for modelling of pyramidal hollow microneedles for transdermal drug delivery" حسب Rahul Nadda (19435999)

"…<p dir="ltr">Supplementary files for article "Incorporating fluid-structure interactions for modelling of pyramidal hollow microneedles for transdermal drug delivery"<br><br>ollow microneedles (HMNs) have gained significant attention as a potential alternative to traditional hypo?…"

Ketamine wash-in. حسب Anne S. Fleiner (20496284)

"…(ii) The change in post-burst spiking after the wash-in of 20 μM and 100 μM was not significant compared to the control (MWU test). However, the decrease in post-burst spiking was significantly larger after the wash-in of 100 μM ketamine than with 20 μM (MWU test). …"

Image 3_Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials... حسب Virginie Piffaut (22399978)

"…</p>Results<p>While ascorbic acid did not exhibit any efficacy versus its vehicle in limiting skin hyperpigmentation induced by HEV, the use of 2-MNG (0.5 or 1%) led to an early significant decrease in HEV-induced pigmentation, which was sustained until the end of the study, as evidenced by colorimetry and significantly scored by visual assessment. …"

Image 5_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf حسب Youyi Wu (20786402)

"…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …"

Table 4_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.xlsx حسب Ling Yao (16961)

"…Among non-neoplastic digestive diseases, inflammatory bowel disease showed the most pronounced decrease. In contrast, the burden of colorectal cancer has increased annually across all age groups. …"

Table 2_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx حسب Wei Wei (21173)

"…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …"

Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx حسب Xiaozhen Huang (5858690)

"…Background<p>Isolated growth hormone deficiency type II (IGHD II) is an autosomal dominant disorder characterized by a GH1 gene variant resulting in a significant reduction in growth hormone (GH) secretion and a subsequent decrease of plasma insulin-like growth factor 1 (IGF-1) levels and eventual growth impairment.…"

Table3_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx حسب Bing Cui (179696)

"…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …"

Experiments (Crystal violet assay). حسب Takanori Kitagawa (20727226)

"…YCW-H demonstrated significant anti-proliferative effects on MCF7 cells, reducing cell growth by 58.7% ± 6.9 even when physically separated from the cells by a plastic wall. …"

Image 5_Pronounced impairment of B cell differentiation during bone regeneration in adult immune experienced mice.tiff حسب Mireille Ngokingha Tchouto (20812811)

"…</p>Results<p>While the B cell proportion in young and non-immune experienced animals did not significantly change from 2 to 5 days post osteotomy in the hematoma, we found a significant decrease of the B cell proportion in the immune experienced mice, which was accompanied by the decreased expression of B cell specific genes, suggesting a specific response in immune experienced animals. …"

Cascade Nanozyme-Loaded Sprayable Hydrogels for Fibroblast Rejuvenation and Diabetic Wound Regeneration حسب Xinyi Zhang (36040)

"…Multifunctional composite wound dressings hold significant promise for diabetic wound healing. However, the detrimental role of the advanced glycation end-products (AGEs)-reactive oxygen species (ROS) cycle in impeding wound repair remains underexplored. …"

Table1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pat... حسب Boris Jakopovic (9265517)

"…Even with treatment advancements, the survival rates for these patients remain suboptimal. There is a significant focus on developing multi-targeted therapies due to the common issue of drug resistance in standard and targeted cancer treatments. …"

Scenario 1. Moderate patient with STAT-ON™. حسب Daniel Rodriguez-Martin (22411006)

"…<div><p>Parkinson’s Disease (PD) is a progressive neurodegenerative disorder affecting millions of patients worldwide, with significant economic and social implications. The increasing prevalence of PD, coupled with rising healthcare costs, necessitates cost-effective solutions for patient management. …"

Table 4_Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021.doc حسب Shujun Tan (20011518)

"…</p>Results<p>The global burden of NE has significantly declined over the past three decades. Between 1990 and 2021, the global ASIR decreased from 20.22 to 17.16, while the number of cases fell from 1,295,891.1 to 1,061,448.15, reflecting an 18.09% reduction. …"

Electrophysiological characterization of <i>C. elegans</i> body-wall muscles. حسب Xuexing Du (20624042)

"…The top section of each column illustrates the currents in different mutants, while the bottom section depicts the ionic currents obtained by subtracting the corresponding mutant currents from the total wild type (WT) currents, highlighting a significant decrease in <i>shk-1(lf)</i> and a slight reduction in <i>slo-2(lf)</i> mutants. …"