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19941
Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
Published 2025“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
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19942
Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx
Published 2025“…Cellular experiments using A549 and Beas2B cells showed that PIN significantly reduced TGF-β1-induced mesenchymal marker expression while increasing epithelial marker expression. …”
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19943
Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
Published 2025“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
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19944
Unraveling Microplastic Effects on Gut Microbiota across Various Animals Using Machine Learning
Published 2024“…Microplastics, rapidly expanding and durable pollutant, have been shown to significantly impact gut microbiota across a spectrum of animal species. …”
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19945
DataSheet1_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx
Published 2024“…KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. MdKAI2 was markedly upregulated by PEG stress and significantly promoted the growth of apple calli under nonstress conditions, whereas it was significantly inhibited under 20% PEG stress, as was cell death. …”
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19946
DataSheet2_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx
Published 2024“…KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. MdKAI2 was markedly upregulated by PEG stress and significantly promoted the growth of apple calli under nonstress conditions, whereas it was significantly inhibited under 20% PEG stress, as was cell death. …”
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19947
Hemostatic changes following COVID-19 vaccination: Do they promote a pro-thrombotic state?
Published 2024“…BNT162b2 group platelet counts increased significantly on day 7 (<i>p</i> = .010). TGA parameters in the ChAdOx1-S group decreased significantly in ETP levels (<i>p</i> = .007) and peak concentrations (<i>p</i> = .041) over time while those of the BNT162b2 group were stable (median ETP levels and peak concentrations; <i>p</i> > .05). …”
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19948
Table 1_Epidemiological characteristics and trends of pre-hospital emergency care in Handan, China from 2011 to 2024.docx
Published 2025“…Over the past 14 years, Handan’s pre-hospital EMS demand increased significantly by 3.11-fold (p < 0.001). The percentages of EMS patients aged 61 to 70 and over 71 years old increased significantly (p < 0.01), in contrast, the percentage of EMS patients aged 21 to 30 and 31 to 40 years old decreased significantly (p < 0.01). …”
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19949
Data Sheet 1_Dietary supplementation with polypeptin and bioture improves growth, feed utilization, antioxidant capacity, and disease resistance in juvenile hybrid grouper (Epineph...
Published 2025“…The results showed that co-supplementation significantly improved multiple performance indicators, exhibiting notable synergistic effects: final body weight, weight gain, and specific growth rate increased, while feed conversion ratio and hepatosomatic index decreased. …”
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19950
Effect of TRPML1 on inflammation in lymphedema mice.
Published 2024“…Compared with that of the SHAM group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes in the WT group was significantly increased. Compared with that in the WT group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes was significantly decreased in the TRPML1<sup>−/−</sup> group (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001).…”
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19951
De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response.
Published 2025“…<p><b>(A)</b> Volcano plot of ATAC-seq results for sequence repeats with increased (blue) and decreased (red) chromatin accessibility in ATRX-null microglia. …”
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19952
Aligned fibers cause higher <i>Plithotaxis</i> within monolayer.
Published 2025“…For all quintiles, <i>φ</i> distributions are significantly different between AF and RF (p<0.001 for <b>c-e</b>, p<0.05 for <b>f</b>). …”
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19953
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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19954
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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19955
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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19956
Experiment 3 –trial E.
Published 2024“…Violin plots show Cq median (solid line). Statistical significance levels were calculated with the GraphPad Prism v9.3.1 (* = p ≤ 0.05; n = 3).…”
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19957
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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19958
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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19959
Cytochrome bd-II oxidase CyxA promotes the pathogenicity of <i>Klebsiella pneumoniae</i> by resisting oxidative stress
Published 2025“…Additionally, the expression levels of <i>cyxA</i> at 37°C and 41°C were significantly higher compared to 30°C, and the Δ<i>cyxA</i> strain exhibited significantly lower viable counts, elevated intracellular reactive oxygen species (ROS) levels, and decreased total antioxidant capacity (T-AOC) relative to WT at 37°C and 41°C. …”
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19960
ABR wave I and IV parameters in response to clicks.
Published 2025“…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …”