Image 3_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif حسب Minzhen Deng (11267109)

"…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …"

Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif حسب Minzhen Deng (11267109)

"…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …"

Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif حسب Minzhen Deng (11267109)

"…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …"

DataSheet1_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx حسب Hongyang Guo (9466516)

"…KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. MdKAI2 was markedly upregulated by PEG stress and significantly promoted the growth of apple calli under nonstress conditions, whereas it was significantly inhibited under 20% PEG stress, as was cell death. …"

DataSheet2_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx حسب Hongyang Guo (9466516)

"…KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. MdKAI2 was markedly upregulated by PEG stress and significantly promoted the growth of apple calli under nonstress conditions, whereas it was significantly inhibited under 20% PEG stress, as was cell death. …"

Data Sheet 1_Dietary supplementation with polypeptin and bioture improves growth, feed utilization, antioxidant capacity, and disease resistance in juvenile hybrid grouper (Epineph... حسب Futao Jing (22516817)

"…The results showed that co-supplementation significantly improved multiple performance indicators, exhibiting notable synergistic effects: final body weight, weight gain, and specific growth rate increased, while feed conversion ratio and hepatosomatic index decreased. …"

De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response. حسب Sarfraz Shafiq (13259589)

"…<p><b>(A)</b> Volcano plot of ATAC-seq results for sequence repeats with increased (blue) and decreased (red) chromatin accessibility in ATRX-null microglia. …"

Cytochrome bd-II oxidase CyxA promotes the pathogenicity of <i>Klebsiella pneumoniae</i> by resisting oxidative stress حسب Xiao Xiao (99147)

"…Additionally, the expression levels of <i>cyxA</i> at 37°C and 41°C were significantly higher compared to 30°C, and the Δ<i>cyxA</i> strain exhibited significantly lower viable counts, elevated intracellular reactive oxygen species (ROS) levels, and decreased total antioxidant capacity (T-AOC) relative to WT at 37°C and 41°C. …"

ABR wave I and IV parameters in response to clicks. حسب Carolin Jüchter (17384611)

"…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …"

Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx حسب Lei Jin (120473)

"…High-risk ARG abundance significantly increased from 404.7 in manure to 843.2 in slurries, with health-risk scores rising 1.88-fold during anaerobic digestion. …"

Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy حسب Ya-yin Tan (21448519)

"…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …"

Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

"…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"

Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf حسب Na He (295300)

"…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …"

Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg حسب Mailén Rojo (10802556)

"…</p>Results<p>Our findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …"

Image 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf حسب Melissa S. Monson (8281047)

"…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …"

Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function حسب Xialin Li (20449207)

"…Roxadustat also remarkably decreased the expression of KIM-1 and NGAL. Furthermore, roxadustat significantly abolished the expression of Bax and cleaved caspase 3, two apoptosis marker proteins. …"

Table 4_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx حسب Junzhe Chen (5729912)

"…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …"

Table 1_Evaluation of a multi-epitope vaccine PME for Pasteurella multocida in mouse model.docx حسب Rui Zhang (13940)

"…Furthermore, the pathological lung damages in the His-PME group and the pcDNA3.1-PME group were significantly alleviated, and the bacterial loads in lung tissues were significantly decreased. …"

Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

"…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"

Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf حسب Na He (295300)

"…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …"