Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
Get full text
Get full text
Get full text

The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis by Hoda Gad (6470522)

“…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …”

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma Younes (6424865)

“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”

Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens by Sheraz Ahmed Bhatti (9759633)

“…Dietary OTA at all the tested levels induced the hepatic and renal tissue injury as indicated by significant decreased total antioxidant capacity in these organs along with significant decreased (p ≤ 0.05) serum concentrations of total proteins and albumin. …”

A Neighborhood Framework for Resource-Lean Content Flagging by Sheikh Muhammad Sarwar (19517701)

“…Our evaluation results on eight languages from two different datasets for abusive language detection show sizable improvements of up to 9.5 F1 points absolute (for Italian) over strong baselines. …”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

“…Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …”

Multi-IsnadSet MIS for Sahih Muslim Hadith with chain of narrators, based on multiple ISNAD by Aziz Mehmood Farooqi (20748788)

“…The graph representation of the authentic and manually curated dataset will open ways for the development of computational models that could identify the significance of a chain and a narrator. …”

A customised fetal growth and birthweight standard for Qatar: a population-based cohort study by Thomas Farrell (3933833)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Perinatal Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1515/jpm-2024-0060" target="_blank">https://dx.doi.org/10.1515/jpm-2024-0060</a></p>…”

Fixing a heart valve by Nature Research (16552612)

“…All of these factors significantly increase the rate of complications following valve replacement, so valve repair is a more viable option in these parts of the world. …”

Improving the performance of a commercial absorption cooling system by using ejector: A theoretical study by Hamza K. Mukhtar (17821004)

“…An improvement of 70.6% in the COP was obtained at the design condition. A parametric analysis was implemented to study the significance of the key parameters in the RACS performance. …”

A clustering metaheuristic for large orienteering problems by Almiqdad Elzein (13141038)

“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”

Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis by Ayman El-Menyar (440103)

“…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …”

Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion by Al-Dimassi, Saleh

“…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …”
Get full text
Get full text
Get full text
Get full text

When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial by Hourani, R.

“…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …”
Get full text
Get full text
Get full text
Get full text

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar by Shuja Mohd Reagu (12051406)

“…</p><h3>Conclusions</h3><p dir="ltr">The rates of Obsessive–compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. The obsessive–compulsive symptoms and the intent to not breastfeed were significantly associated with fear of infection to the new-born. …”

The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)

“…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …”

Feasibility of a group-based laughter yoga therapy on anxiety and happiness among community-dwelling older adults: A quasi-experimental study by Mona Metwally El-Sayed (17725127)

“…</p><p><br></p><h3>Results</h3><p dir="ltr">A statistically significant decrease in anxiety level among the study group compared to the control group (Pre = 16.68 (7.35), immediate = 6.65 (2.89), post three-month = 7.68 (2.75), p=<0.001 and effect size = 0.715). …”

A component analysis of positive behaviour support plans by Grey, Ian

“…Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. No single intervention component was found to have a greater association with reductions in challenging behaviour…”
Get full text
Get full text
Get full text
Get full text

A snapshot of current medical research: The notion of supply and demand by Almutairi, Adel F.

“…Therefore, it is time to be more selective and innovative with our research in order to have a significant positive impact on healthcare services.…”
Get full text
Get full text
Get full text

Modulation of gut microbiota: The effects of a fruits and vegetables supplement by Arun Prasath Lakshmanan (6807152)

“…The gut microbiome composition, measured by 16S rDNA sequencing, showed no difference in both alpha and beta diversities, whereas the LEfse analysis revealed a microbial shift after the treatment, with a decreased abundance of the genus <i>Ruminococcus</i> from the Lachnospiraceae family (<i>p</i> = 0.009), and the unclassified genus from the family Erysipelotrichaceae (UC36, <i>p</i> = 0.003) in the FVS group compared with the PLA group (confirmed by SIAMCAT analysis, AUC = 74.1%). …”