Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Forest plots comparing demographic factors within SARS-CoV-2 variant waves. by Rebecca M. Cantu (19787070)

“…Confidence intervals that do not cross 1 on the x-axis are considered significant, with higher numbers associated with increased chances for hospitalization and lower numbers with decreased chances for hospitalization.…”

Presentation1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance fo... by Holger Neb (13018218)

“…Furthermore, nine lipids were decreased (Cer (d18:1/24:0), LacCer (d18:1/16:0), LacCer (d18:1/24:0), sphingosine-1-phosphate S1P (d18:1), S1P (d18:0), the lysophosphatidic acids LPA (16:0), LPA (18:0), LPA (18:1) and 9-HODE. …”

DataSheet1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for s... by Holger Neb (13018218)

“…Furthermore, nine lipids were decreased (Cer (d18:1/24:0), LacCer (d18:1/16:0), LacCer (d18:1/24:0), sphingosine-1-phosphate S1P (d18:1), S1P (d18:0), the lysophosphatidic acids LPA (16:0), LPA (18:0), LPA (18:1) and 9-HODE. …”

Presentation1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance fo... by Holger Neb (13018218)

“…Furthermore, nine lipids were decreased (Cer (d18:1/24:0), LacCer (d18:1/16:0), LacCer (d18:1/24:0), sphingosine-1-phosphate S1P (d18:1), S1P (d18:0), the lysophosphatidic acids LPA (16:0), LPA (18:0), LPA (18:1) and 9-HODE. …”

DataSheet1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for s... by Holger Neb (13018218)

“…Furthermore, nine lipids were decreased (Cer (d18:1/24:0), LacCer (d18:1/16:0), LacCer (d18:1/24:0), sphingosine-1-phosphate S1P (d18:1), S1P (d18:0), the lysophosphatidic acids LPA (16:0), LPA (18:0), LPA (18:1) and 9-HODE. …”

Table 1_Bacillus megaterium NCT-2 agent alters soil nutrients, vegetable quality, and root microecology in secondary salinized soil.docx by Yimin You (11465812)

“…Specifically, the NCT-2 agent significantly increased the aboveground fresh weight, underground fresh weight, total flavonoids, antioxidant enzyme activity, ascorbic acid, Cu, Zn, Fe, P, and K in lettuce, while significantly reduced nitrate. …”

Supplementary file 1_Bacillus megaterium NCT-2 agent alters soil nutrients, vegetable quality, and root microecology in secondary salinized soil.docx by Yimin You (11465812)

“…Specifically, the NCT-2 agent significantly increased the aboveground fresh weight, underground fresh weight, total flavonoids, antioxidant enzyme activity, ascorbic acid, Cu, Zn, Fe, P, and K in lettuce, while significantly reduced nitrate. …”

Table 2_Bacillus megaterium NCT-2 agent alters soil nutrients, vegetable quality, and root microecology in secondary salinized soil.docx by Yimin You (11465812)

“…Specifically, the NCT-2 agent significantly increased the aboveground fresh weight, underground fresh weight, total flavonoids, antioxidant enzyme activity, ascorbic acid, Cu, Zn, Fe, P, and K in lettuce, while significantly reduced nitrate. …”

Supplementary file 1_Identifying early blood glucose trajectories in sepsis linked to distinct long-term outcomes: a K-means clustering study with external validation.docx by Huan Ma (713125)

“…</p>Results<p>Among 3,655 sepsis patients from the FAH-SYSU dataset, we identified 5 distinct clusters of BG trajectories, which were significantly associated with 1-year mortality risk. …”

Comparison of urban stream chemistry from five watersheds prior to P additions to drinking water (spring 2019) and one year after P treatments began (spring 2020) where spring mont... by Anusha Balangoda (22622853)

“…From 2019 to 2020, concentrations of Mg significantly decreased (p < 0.05), as well as TN:TP (p < 0.005).…”

Percent of recording electrodes excited or inhibited by stimulation at different frequencies, amplitudes, and types of electrodes. by Uma R. Mohan (19950039)

“…<p>(<b>a</b>) Percent of recording electrodes showing significant high frequency activity increases and decreases for each stimulation frequency for depth and surface stimulation sites. …”

Image 1_Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11.tif by Li Ling (424480)

“…Moreover, the combination of SAS and ¹³¹I significantly increased the MDA levels and lipid peroxidation, decreased the GSH levels, and suppressed the expression of SLC7A11 and GPX4, while SLC7A11 knockdown significantly enhanced ferroptosis-related markers in DTC cells. …”

Data Sheet 1_Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implicatio... by Liming Liu (107470)

“…Immunophenotyping revealed a GCB-like phenotype in HALs, characterized by elevated CD10 and BCL6 expression and decreased MUM1 and BCL2 expression. Patients with HALs had significantly shorter survival (median: 32.1 vs. 46.1 months, P < 0.001). …”

<b>Fire Severity Alters Soil Microbial Diversity and Community Stability in a Subtropical Forest Ecosystem</b> by Xuezhao (21803957)

“…Moreover, low-severity fires increased the functional taxa associated with chemoheterotrophic and aerobic chemoheterotrophic bacteria, whereas the ectomycorrhizal fungi was significantly reduced in fired plots. Network analysis indicated that the complexity and connectivity of microbial networks gradually decreased with increasing fire severity.…”

Table 1_Impacts of arbuscular mycorrhizal and Trichoderma viride on enhancing physicochemical properties and triggering defense mechanisms of tomato plants challenged with potato v... by Dalia Gamil Aseel (22106561)

“…Interestingly, the dual application significantly suppressed viral symptoms and decreased viral accumulation levels, disease incidence, and disease severity by 88.1%, 40%, and 53.4%, respectively. …”

Supplementary data: Characterization of medical device randomized controlled trials with adaptive designs by Gui Su (128698)

“…The average annual number of adaptive RCTs per 1000 clinical trials was the highest (8.55 ± 11.65) during 2005–2010, reduced to 3.33 ± 2.35 during 2011–2016, and significantly decreased to 1.29 ± 0.85 during 2017–2024 (p = 0.011). …”

Table 1_Spatial yield gains in empty-row optimized rice–crab co-culture are linked to nifH-driven nitrogen compensation in border rows.docx by Tiexin Yang (21423032)

“…We hypothesized that ERC-12 enhances crab activity in empty rows, thereby stimulating nifH-mediated soil nitrogen fixation to offset yield losses caused by reduced planting density.…”

Data Sheet 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.docx by Jingjing Chen (293564)

“…Finally, qRT-PCR confirmed the differential expression of key genes in clinical samples.</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”

Table1_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”