Image 6_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Data Sheet 1_Global, regional, and national burden of hyperglycemia-associated colorectal cancer, 1990-2021: a systemic analysis for the Global Burden of Disease study.zip by Yijuan Liu (5195747)

“…Notably, while mortality-related burdens slightly decreased in high-SDI areas, YLDs continued to rise, indicating unmitigated disability burdens. …”

Table 4_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xls by Guilin Ren (18720749)

“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”

Image 5_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Table 4_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx by Jiahui Chang (15359305)

“…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …”

Table 3_Association between lactate/albumin ratio and 28-day mortality in ICU critical patients with coronary heart disease: a retrospective analysis of the MIMIC-IV database.pdf by Ying Liu (18461)

“…Both elevated lactate levels and decreased albumin levels may reflect the body's stress response and inflammatory reaction. …”

Image 1_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

Granite sample. by Run-Zhi Jia (21262716)

“…As the confining pressure increased, the ratio of tensile cracks in rock sample failure decreased, while the ratio of shear cracks increased. …”

Data Sheet 2_Forecasting the production and export of shrimp in Bangladesh: a policy focused time series analysis.docx by Mobin Hossain Shohan (21495368)

“…Legislative analysis highlights policy gaps, weak enforcement, and insufficient infrastructure as significant barriers to meeting international standards. …”

Data_Sheet_10_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF by Saeid Safiri (3713035)

“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”

Data_Sheet_2_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF by Saeid Safiri (3713035)

“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”

Image 5_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif by Xiaochuan Yu (2410861)

“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”

<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b> by Ge Qiao (21802511)

“…LOXL2 knockdown led to decreased tumor cell proliferation, enhanced apoptosis, and cell cycle arrest. …”

Supplementary Material for: A Case Report of Intravitreal Aflibercept for Iris Metastasis from Small Cell Lung Carcinoma with Neovascular Glaucoma by figshare admin karger (2628495)

“…Although not curative, this therapeutic approach may play a significant role in the symptom management of these patients.…”

Data Sheet 2_Neuron-specific enolase in patients with acute and chronic schizophrenia, diversity of approaches: marker of neuronal death, neurodegeneration or neurodevelopmental th... by Alicja Sierakowska (21248987)

“…</p>Results<p>The mean serum concentration of NSE in patients with schizophrenia was statistically significantly lower than in healthy controls. A weak negative correlation between NSE levels and the SANS score and a weak positive correlation between NSE levels and the SAPS score were found, but the results were not statistically significant. …”

Image 1_Effectiveness of nirsevimab immunization against RSV infection in preterm infants: a systematic review and meta-analysis.tif by Xiaopeng Wang (1424584)

“…</p>Conclusion<p>Nirsevimab significantly decreases the risk of RSV-related infection in preterm infants and represents a valuable intervention for RSV prevention in this vulnerable population.…”

Figure 4 from OATP1B-type Transport Function Is a Determinant of Aromatase Inhibitor–Associated Arthralgia Susceptibility by Hanieh Taheri (20944284)

“…<p>OATP1B deficiency results in elevated AI plasma exposure and decreased liver accumulation. <b>A,</b> Pharmacokinetic profile of letrozole after a single oral dose of 10 mg/kg in wild-type and Oatp1a/1b^(−/−) mice. …”

Evaluation standards of the CCD. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Image 5_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

DataSheet1_Accumulation of coumaric acid is a key factor in tobacco continuous cropping obstacles.docx by Meng Jia (696568)

“…Introduction<p>Phenolic acids are believed to play a significant role in tobacco continuous cropping obstacles, but the strength and potential mechanisms of different phenolic acids remain unclear.…”