ZIKV infection enriches the HLA Class I pathway in brain tumour cells. by Matt Sherwood (22530221)

“…Normalised enrichment score (NES) denotes the degree to which the enrichment increased (+) or decreased (-). GSEA analysis significance is defined by p ≤ 0.05 and FDR ≤ 0.25. …”

The expression of PAX7 and MYOD1 correlate with differential expression of diverse chemokines in HuMuSC. by Katharine Striedinger (15503387)

“…Using linear regression PAX7 slope varies significantly p = 0.0001 and MYOD1 slope also varies significantly p = 0.05 n = 3 <b>(b)</b> Heat map displaying the expression levels of all cytokine protein detected in HuMuSC from collection as they activate progressively at day 0, day 3 and day 6 <i>in vitro</i>, using the high throughput proteomic Multiplex assay. …”

Table 1_Engineered miR-214 enriched Schwann cell-derived extracellular vesicles amplify therapeutic efficacy for peripheral neuropathy in T2D mice.docx by Lei Wang (6656)

“…Furthermore, 214-EVs markedly suppressed neuroinflammation by decreasing CD68 + macrophages and inactivating the TLR4/NF-κB signaling pathway. …”

Data Sheet 1_Impact of SARS-CoV-2 vaccination and of seasonal variations on the innate immune inflammatory response.pdf by Hend Jarras (13138641)

“…</p>Results<p>Our results show that IL-8 production after stimulation decreased after vaccination. In addition, the IL-8 response was significantly different depending on the season when the visit occurred, for both COVID-19 vaccinated and unvaccinated individuals.…”

Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx by Xin Yu (124814)

“…Cellular experiments using A549 and Beas2B cells showed that PIN significantly reduced TGF-β1-induced mesenchymal marker expression while increasing epithelial marker expression. …”

Table 1_Epidemiological characteristics and trends of pre-hospital emergency care in Handan, China from 2011 to 2024.docx by Feng Tian (121350)

“…Over the past 14 years, Handan’s pre-hospital EMS demand increased significantly by 3.11-fold (p < 0.001). The percentages of EMS patients aged 61 to 70 and over 71 years old increased significantly (p < 0.01), in contrast, the percentage of EMS patients aged 21 to 30 and 31 to 40 years old decreased significantly (p < 0.01). …”

Data Sheet 1_Dietary supplementation with polypeptin and bioture improves growth, feed utilization, antioxidant capacity, and disease resistance in juvenile hybrid grouper (Epineph... by Futao Jing (22516817)

“…The results showed that co-supplementation significantly improved multiple performance indicators, exhibiting notable synergistic effects: final body weight, weight gain, and specific growth rate increased, while feed conversion ratio and hepatosomatic index decreased. …”

Effect of TRPML1 on inflammation in lymphedema mice. by Lijie Yang (694492)

“…Compared with that of the SHAM group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes in the WT group was significantly increased. Compared with that in the WT group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes was significantly decreased in the TRPML1^−/− group (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001).…”

De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response. by Sarfraz Shafiq (13259589)

“…<p><b>(A)</b> Volcano plot of ATAC-seq results for sequence repeats with increased (blue) and decreased (red) chromatin accessibility in ATRX-null microglia. …”

Aligned fibers cause higher <i>Plithotaxis</i> within monolayer. by Amrit Bagchi (20536044)

“…For all quintiles, <i>φ</i> distributions are significantly different between AF and RF (p<0.001 for <b>c-e</b>, p<0.05 for <b>f</b>). …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”

Experiment 3 –trial E. by Ottavia Benedicenti (9100619)

“…Violin plots show Cq median (solid line). Statistical significance levels were calculated with the GraphPad Prism v9.3.1 (* = p ≤ 0.05; n = 3).…”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”

ABR wave I and IV parameters in response to clicks. by Carolin Jüchter (17384611)

“…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …”

Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

“…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”

Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf by Rongrong Huang (819212)

“…Symptoms of pneumonia in STING-KO mice infected with PR8 were significantly milder than those in WT mice, and NETs were less likely to form in the lung tissue of STING-KO mice. …”

Table 3_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx by Kaihao Lin (13016658)

“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”