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201
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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202
Second-law-based performance evaluation of cooling towers and evaporative heat exchangers
Published 2020“…For the different input variables investigated, efficiencies were, almost always, seen to increase or decrease monotonically. We notice that an increase in the inlet wet bulb temperature invariably increases the second-law efficiency of all the heat exchangers. …”
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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells
Published 2008“…The activation of signal transducer and activator of transcription 3 (STAT3) has been identified as a key mediator that drives the fundamental components of melanoma malignancy, including immune suppression in melanoma patients. …”
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205
The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013)
Published 2013“…The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. In addition, a decrease in CDC42 activation levels, and an increase in Rac activation were detected. …”
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Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis
Published 2023“…<h3>Background</h3><p dir="ltr">The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”
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208
Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
Published 2024“…During the first year of the pandemic, Lebanon implemented multiple lockdowns during which SHS endured repetitive closures. We explore the impact of the pandemic on SHS delivery and the diagnosis rate of sexually transmitted infections (STIs) among attendees of a large sexual health clinic in Beirut, Lebanon. …”
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209
Cytokine-Mediated Dysregulation of Signaling Pathways in the Pathogenesis of Multiple Myeloma
Published 2020“…The imbalance between inflammatory and anti-inflammatory cytokines in MM leads to an increased level of pro-inflammatory cytokines, which in turn play a significant role in dysregulation of signaling pathways and proliferation of MM cells; however, the association appears to be inadequate and needs more research. …”
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The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells
Published 2020“…Western blot analysis on MDA-MB-231 cells treated with C3 showed a significant increase in BAX/Bcl2 ratio with no significant effect on Pro-caspase-3 expression. …”
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masterThesis -
211
Managing Endothelial Dysfunction in COVID-19
Published 2022“…The median(Interquartile range) time to recovery was not significantly different between the endothelial protocol group (6 [4-12] days) and the placebo group (6 [5-8]days)(p-value = 0.854). …”
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The impact of water table fluctuation and salinity on LNAPL distribution and geochemical properties in the smear zone under completely anaerobic conditions
Published 2023“…At the source zone, benzene and toluene reached their maximum concentration after 30 and 10 days for the stable and the fluctuating columns, respectively. Significant decrease in benzene and toluene concentrations occurred under the fluctuating water table. …”
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Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
Published 2025“…Meta-regression showed a significant decrease in SSI incidence in HICs. Maternal factors, procedural aspects, and care quality were associated with SSI. …”
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214
IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…Background: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. We have shown previously that IL-1 activates phospholipid signaling pathways in intestinal epithelial cells (IEC), leading to increased ceramide levels. …”
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215
Redox Homeostasis and Inflammation Responses to Training in Adolescent Athletes: a Systematic Review and Meta-analysis
Published 2020“…</p><h3>Conclusions</h3><p dir="ltr">The results showed significant alterations in oxidative stress and cytokine levels after acute exercise, ranging from moderate to extremely large. …”
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Phase-separated polyvinylidene fluoride/ZnO composite microspheres as sunlight-driven photocatalysts
Published 2024“…Moreover, the presence of ZnO active photocatalytic sites induces active dye degradation. …”
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Wave-packet dynamics in monolayer graphene with periodic scattering potentials
Published 2025“…The time propagation of the wave packets is calculated using the split-operator method for different sizes, heights, and separations of the barriers. We found that, despite the pronounced Klein <u>tunneling</u> effect in graphene, the presence of a lattice of defects significantly impacts the propagation properties of the wave packets. …”
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Effect of COVID-19 on the Generation of Waste in Marrakech, Morocco
Published 2021“…<h3>Background</h3><p dir="ltr">The production of solid waste continues to increase as the population and standard of living increases. …”
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20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway
Published 2013“…In conclusion, we show that hyperglycemia in diabetes has a significant effect on the expression of Arachidonic Acid (AA)-metabolizing CYPs, manifested by increased AA metabolism, and might thus alter kidney function through alteration of type and amount of AA metabolites.…”