Presentation 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... by Gyeong Ho Baek (21382907)

“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”

Image_1_Barriers of the CNS transfer rate dynamics in patients with vascular cognitive impairment and dementia.TIFF by Saeid Taheri (339331)

“…</p>Results<p>Longitudinal BBB measurements revealed variable dynamic behavior: after two years, the BBB K_trans increased in 55% of patients and decreased in the remaining 45% unpredictably. …”

<b>Seizure-induced changes in cytokine expression and dysregulation of plasminogen activation and IGF systems following kainic acid administration in rats</b> by Elena Suleymanova (22195777)

“…We also observed disruption of the IGF system, characterized by decreased IGFBP-5 protein levels in the hippocampus and downregulation of <i>Igfbp5</i> mRNA in both hippocampus and cortex. …”

Image 2_Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset.tif by Tianqi Xu (9574329)

“…</p>Results<p>In patients with LPD, we found reduced CSA in the right supramarginal gyrus (SMG), right precuneus (PCUN), left inferior parietal lobule (IPL), and left lingual gyrus (LING) compared to RPD, while no significant differences in CT were found between the two groups. …”

Data Sheet 1_Evaluation of tolerability and safety of transcranial electrical stimulation with gel particle electrodes in healthy subjects.pdf by Chuangchuang Chang (20179632)

“…Additionally, fatigue increased, and energy levels decreased on VAMS-R with longer durations. No significant differences were found in other neuropsychological tests.…”

Image 1_Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset.tif by Tianqi Xu (9574329)

“…</p>Results<p>In patients with LPD, we found reduced CSA in the right supramarginal gyrus (SMG), right precuneus (PCUN), left inferior parietal lobule (IPL), and left lingual gyrus (LING) compared to RPD, while no significant differences in CT were found between the two groups. …”

Image 3_Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset.tif by Tianqi Xu (9574329)

“…</p>Results<p>In patients with LPD, we found reduced CSA in the right supramarginal gyrus (SMG), right precuneus (PCUN), left inferior parietal lobule (IPL), and left lingual gyrus (LING) compared to RPD, while no significant differences in CT were found between the two groups. …”

Presentation 1_Gender and age differences in the global burden of peptic ulcers: an analysis based on GBD data from 1990 to 2021.zip by Ruirui Tan (21188585)

“…The global prevalence is expected to improve, while PU-related mortality is likely to plateau without significant increases or decreases.</p>Conclusion<p>The global burden of PU has declined significantly over the past three decades. …”

Supplemental Figures by Danielle A. Jeffrey (21187329)

“…Significantly, we are the first to report a reduction in the muscle-specific isoforms of FXR1 in pediatric DCM patients, underscoring an age-specific regulation of FXR1 expression.…”

Data Sheet 1_Invasive treatment strategy for older patients with non-ST-elevation acute coronary syndrome: a systematic review and meta-analysis of randomized controlled trials.pdf by Vaibhav Vats (18702889)

“…Invasive management significantly decreased the risk of MI (RR 0.70, 95% CI: 0.55, 0.89) and revascularization (RR 0.29, 95% CI: 0.21, 0.40). …”

Data Sheet 1_Global, regional, and national burden of thyroid cancer in women of child-bearing age, 1990 to 2021 and predictions to 2035: An analysis of the global burden of diseas... by Tao Jiang (28401)

“…</p>Conclusion<p>Over the past 30 years, thyroid cancer incidence among women has significantly increased globally, with slightly declining mortality and DALYs rates. …”

Data Sheet 1_Freshwater transport variation through Fram and Davis Strait influenced by atmospheric circulation.pdf by Jinlong Zhang (175134)

“…The research findings reveal that over the past four decades, the FWT through the straits has not exhibited the anticipated continuous growth. Instead, we observed distinct temporal shifts in regional freshwater export patterns: The FWT in Fram Strait experienced significant increase prior to the 21st century (trend of 10.14 mSv/10yr during 1980-2000), whereas the FWT in Davis Strait showed acceleration after 2000 (trend of 13.69 mSv/10yr). …”

Mendelian randomization analysis revealed that albuminuria is the key factor affecting socioeconomic status in CKD patients by Jianbo Qing (12864269)

“…In the multivariable MR analysis, both CKD (OR = 0.867, 95% CI: 0.786–0.957, <i>p</i> = 0.0045) and eGFR (OR = 0.065, 95% CI: 0.010–0.437, <i>p</i> = 0.0049) exhibited significant effects on income. This study underscores that higher albuminuria levels in CKD patients are associated with decreased income and emphasizes the importance of effective management and treatment of albuminuria in CKD patients to mitigate both social and personal economic burdens.…”

Data Sheet 1_Factors affecting posaconazole plasma concentrations: a meta-analysis and systematic review.docx by Ruochen Qu (16946790)

“…Neither vomiting nor mucositis significantly affected POS concentrations. Acid-suppressing agents, such as H2 receptor antagonists and proton pump inhibitors, notably decreased POS concentrations but had no significant effect on DRT. …”

Long-term tillage and cover cropping differentially influenced soil nitrous oxide emissions from cotton cropping system by Debasish Saha (17481384)

“…However, their influence on nitrous oxide (N₂O) emissions varies, with the potential of both increasing and decreasing N₂O emissions. …”

Image 1_Tricuspid annuloplasty in ischemic cardiomyopathy patients undergoing restrictive mitral annuloplasty.tif by Yusuke Misumi (14501381)

“…The primary endpoint was freedom from significant recurrence (i.e., moderate or greater) and progression (≥2+ grades) in TR. …”

Data Sheet 1_Efficacy and safety of topical minocycline preparations for papulopustular rosacea: a systematic review and meta-analysis.pdf by Awadh Alamri (20970752)

“…Topical minocycline allow the delivery of high concentrations of the medication to the skin while decreasing systemic exposure thereby evading side effects (Jones et al., 2021, Webster et al., 2020). …”

The effect of IFN-β and Vit D on the NF-κB gene expression. by Farzad Nasri (8941850)

“…Two lower concentrations of Vit D induced a reduction in the NF-κB expression compared to the control, while the highest concentration increased it significantly <b>(B)</b>. In the co-treatment groups, a dose-dependent decrease pattern among different concentration was seen in the NF-κB expression, but generally it was increased compared to the control <b>(C)</b>. …”

Example of a choice set for Best Worst Scaling. by Yachiyo Tobita (20613887)

“…<div><p>The COVID-19 pandemic triggered social and economic stagnation worldwide, significantly impacting people’s lives. In addition, the Russia-Ukraine war that began in 2022 resulted in rising food prices globally, severely affecting low- and middle-income countries. …”

Data Sheet 1_Utility of nonlinear analysis of heart rate variability in early detection of metabolic syndrome.docx by José Alberto Zamora-Justo (21590657)

“…Introduction<p>Metabolic syndrome (MetS) is a clinical condition characterized by multiple risk factors that significantly increase the likelihood of developing cardiovascular diseases and type 2 diabetes. …”