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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”
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202
Shades of sustainability: A comprehensive analysis of the carbon footprint in conventional blue ammonia and urea manufacturing processes
Published 2025“…However, this integration also increases indirect emissions due to higher energy demands, with electricity-related emissions rising by 9.9%. …”
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203
Carbon Nanotube Effect on the Ductility, Flexural Strength, and Permeability of Concrete
Published 2019“…<p>Recently, remarkable types of carbon nanofilaments called carbon nanotubes (CNTs) have raised the interest of many concrete and cementitious composite researchers due to their significant mechanical, electrical, thermal, kinetic, and chemical properties. …”
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204
Pioglitazone Effect on Clinical Outcome and Inflammatory Response in patients with type 2 diabetes mellitus and COVID-19: A Randomized Clinical Trial
Published 2024“…Twenty-eight participants met the primary clinical composite outcome. There was no significant difference in the incidence of primary outcome between subjects receiving placebo (n=14) and pioglitazone (n=14). …”
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Meal pattern of male rats maintained on histidine-, leucine-, or tyrosine-supplemented diet.
Published 2007“…Histidine supplementation reduced diurnal meal size by 42% (p 0.05), whereas that of leucine increased nocturnal meal size by 35% (p 0.05). Tyrosine supplementation increased food intake of the nocturnal period and decreased that of the diurnal period. …”
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207
Revealing the Adoption Factors of Electric Vehicles in Dubai
Published 2024“…Surprisingly, the research fails to provide enough evidence to prove the claim that the sufficient availability of charging infrastructure has a positive impact on the willingness to adopt EVs. This research provides significant insights into the dynamics of EV adoption in Dubai. …”
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208
A snapshot of current medical research: The notion of supply and demand
Published 2017“…Therefore, it is time to be more selective and innovative with our research in order to have a significant positive impact on healthcare services.…”
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209
Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems
Published 2023“…The seed radicle lengths at 2 mg mL−1 were significantly reduced for both plant species. The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …”
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210
EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
Published 2020“…Behaviorally, all subjects demonstrated vigilance decrement as reflected by the significant increase in response time and reduced accuracy. …”
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211
Board independence and managerial authority
Published 2018“…For certain firms, increasing the number of independent directors may impose costs that exceed the benefits. …”
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212
Numerical analysis of combustion characteristics and emissions of recycled flare gas in ethylene cracking furnaces
Published 2025“…<p dir="ltr">Flaring <u>hydrocarbon gases</u> is a common practice in petrochemical plants, contributing to significant greenhouse gas (GHG) emissions and resource wastage. …”
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213
Struvite Recovery from Anaerobically Digested Dairy Manure: A Review of Application Potential and Hindrances
Published 2016“…However, the complex chemical composition of digested dairy manure presents hindrances to struvite recovery. …”
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214
Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages
Published 2020“…We found high levels of granulocytic myeloid cells (GMCs) in whole blood, but their levels were significantly lower in PBMCs. Importantly, we found significantly higher levels of GMCs in the TME compared to NT. …”
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215
A Comparative Study of Safety Outcomes of Sodium Glucose Cotransporter-2 Inhibitors and Loop Diuretics Among Diabetic Patients Using Real-world Data
Published 2022“…The concurrent use of SGLT2 inhibitors and loop diuretics was tolerated at 1 month; however, it resulted in a significant increase in volume-depletion events at 12 months (10.2% vs 1.7%; aHR = 7.03, 95% CI (1.80-27.37), <i>P</i>-value = 0.005). …”
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216
Causes of Delay in Construction Projects in Oil and Gas Construction Industry
Published 2017“…With regard to design, the contractor’s need to decrease construction costs through a cheaper design was found to be a factor in design changes. …”
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A comprehensive review on the use of natural fibers in cement/geopolymer concrete: A step towards sustainability
Published 2023“…In recent years, the usage of fibers has tremendously increased to make significantly robust structures. …”
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Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19
Published 2021“…However, the was no statistically significant difference in the occurrence of major or minor bleeds, ICU admission or the composite outcome of in-hospital mortality, ICU admission or the need for mechanical ventilation. …”
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Akkermansia, a Possible Microbial Marker for Poor Glycemic Control in Qataris Children Consuming Arabic Diet—A Pilot Study on Pediatric T1DM in Qatar
Published 2021“…The stool sample was used to measure microbial composition by 16s rDNA sequencing method. The results have revealed that the subjects who had undergone CSII therapy had increased microbial diversity and genus <i>Akkermansia</i> was significantly enriched in the subjects without CSII therapy. …”
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220
2D magnesium phosphate resorbable coating to enhance cell adhesion on titanium surfaces
Published 2024“…The deposited MgPi coating has good adhesion to the Ti-substrates. Most significantly, compared to uncoated control (Ti) (p < 0.005) and chemically treated coated samples CT-MgPi (p < 0.005), MC3T3-E1 cell proliferation was significantly increased on thermochemical coated surfaces. …”
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