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The retention of health human resources in primary healthcare centers in Lebanon
Published 2012“…Background Critical shortages of health human resources (HHR), associated with high turnover rates, have been a concern in many countries around the globe. …”
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Biphasic effects of vitamin D and FGF23 on human osteoclast biology
Published 2015“…In contrast, in terms of activity, 1,25-D had no effect on resorption, whereas FGF23 slightly but significantly increased bone resorption; 25-D had no effects on either differentiation or on activity. …”
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Human Action Recognition: A Taxonomy-Based Survey, Updates, and Opportunities
Published 2023“…One of the most challenging issues for computer vision is the automatic and precise identification of human activities. A significant increase in feature learning-based representations for action recognition has emerged in recent years, due to the widespread use of deep learning-based features. …”
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The antiproliferative and pro-apoptotic effect of kefir on human leukemic cell lines. (c2008)
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RFX3 is essential for the generation of functional human pancreatic islets from stem cells
Published 2025“…The loss of <i>RFX3</i> disrupted pancreatic endocrine gene regulation, reduced the number of hormone-secreting islet cells and impaired beta cell function and insulin secretion. Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …”
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Advancing human and social dimensions in balanced scorecards for GCC corporations: a nuanced approach
Published 2024“…This research emphasizes the critical need to embed human and social metrics into these systems. This need is particularly pronounced in the dynamic corporate world, where Environmental, Social, and Governance (ESG), Diversity, Equity, and Inclusion (DEI) criteria and sustainability imperatives are increasingly at the forefront. …”
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A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein
Published 2016“…Therefore, we developed a sensitive high-throughput duplex assay quantifying total and pS129 human asyn (h-asyn) in the same well hence improving accuracy as well as saving time, consumables and samples.…”
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…In females, although no correlation between LINE-1 or Alu methylation and hormone levels was observed, a significant stable individual specific level of methylation was noted. …”
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Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy
Published 2024“…Viral malignancies represent a distinct entity among cancers. Oncoviruses like the Human Papilloma Virus (HPV) and the Epstein Barr Virus (EBV) are highly potent inducers of oncogenic transformation leading to tumor development. …”
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Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy
Published 2024“…Oncoviruses like the <u>Human Papilloma Virus</u> (HPV) and the <u>Epstein Barr Virus</u> (EBV) are highly potent inducers of oncogenic transformation leading to tumor development. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes
Published 2021“…In EHT, FAO was significantly higher than in monolayer cells or those on static scaffolds and could be further increased by culture with oleate and WY-14643. …”
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Modulation of Human Valve Interstitial Cell Phenotype and Function Using a Fibroblast Growth Factor 2 Formulation
Published 2015“…This study assessed a fibroblast culture media formulation for its ability to maintain the phenotype and function of VICs as in the intact healthy valve. Normal human VICs were cultured separately in standard DMEM and in fibroblast media consisting of FGF2 (10ng/ml), insulin (50ng/ml) and 2% FCS for at least a week. …”
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p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-Cells
Published 2023“…Inhibition of p53 using pifithrin-μ (PFT-μ) at the MPC stage resulted in a significant increase in the number of PDX1+/NKX6.1+ cells and a reduction in the number of CHGA+/NKX6.1− cells. …”
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Rapid climate changes and human dynamics during the holocene in the eastern mediterranean (Lower Strymon Valley, northern Greece)
Published 2023“…The first signs of human disturbance of the landscape at regional scale occurred toward 5.2 ka cal BP (onset of the Early Bronze Age). …”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…<p>Tumor progression through immune evasion is a major challenge in cancer therapy. Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. …”
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
Published 2018“…Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …”
