Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…<h3>Background</h3><p dir="ltr">Lack of Schlafen family member 11 (SLFN11) expression has been recently identified as a dominant genomic determinant of response to DNA damaging agents in numerous cancer types. Thus, several strategies aimed at increasing SLFN11 are explored to restore chemosensitivity of refractory cancers. …"

Strain response of hot-mix asphalt overlays for bottom-up reflective cracking حسب Ghauch, Ziad G.

"…Moreover, the rate of horizontal strain accumulation increases with higher overlay thickness. Although initial strain values were higher at positive pavement temperature distributions, the corresponding rate of strain increase were higher at negative pavement temperatures. …"
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…"

A Multidecadal Assessment of Drought Intensification in the Middle East and North Africa: The Role of Global Warming and Rainfall Deficit حسب Ahmed El Kenawy (7510103)

"…For example, in comparison to the SPI, the SPEI indicated an increase of 15% in the areas affected by severe to very extreme droughts in arid regions (Aw). …"

Turkronicles: diachronic resources for the fast evolving Turkish language حسب Togay Yazar (22828175)

"…Our analysis reveals that the vocabulary has changed significantly and multiple spellings exist for several words. …"

Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment حسب Seán Fitzgerald (721911)

"…Low TRIM28 epithelium to stroma ratios were associated with elevated levels of caspases 3 and 7 in stroma (p = 0.041 and p = 0.036) and an increased signaling pathway similarity in stromal cells with 81 significant Spearman correlations (ρ ≥ 0.75, p ≤ 0.01).…"

Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women حسب Vijay Ganji (8710491)

"…Serum 25(OH)D appeared to have an inverse ‘U’ association with several adiposity measures. Overall, body adiposity markers were the lowest in the 4th quartile serum 25(OH)D and significantly lower compared to the 1st quartile serum 25(OH)D. …"

Toward a Clearer Understanding of Value‐Based Healthcare: A Concept Analysis حسب Vahe Kehyayan (21241649)

"…The analysis also identified several crucial antecedents for transitioning traditional fee‐for‐service models to those focused on value; it also identified key interrelated consequences: improved patient outcomes, cost reduction, and increased patient satisfaction.…"

Support and attitudes of Qatar mental health professionals to a proposed mental health inpatient smoking ban: Results of a cross‐sectional survey حسب Ashishkumar Badanapurkar (14779579)

"…</h3> <div> <ul> <li>Further staff training is necessary to achieve more consistent attitudes that support a total smoking ban and increase the likelihood of successful implementation.…"

Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study حسب Fahmi Othman (14777506)

"…Compared to PPCI angiograms, the non-PPCI angiograms showed a statistically significant reduction in the percentage of stenosis (71.6± 14.4% vs 64.5± 14.4%, <i>p</i>≤ 0.001), and an increase in minimal luminal diameter (0.82± 0.45 mm vs 1.00± 0.44 mm, <i>p</i>≤ 0.001) of non-culprit lesion. …"

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …"

Synthesis and analysis of silver–copper alloy nanoparticles of different ratios manifest anticancer activity in breast cancer cells حسب Sara Al Tamimi (9692615)

"…Furthermore, we observed the cell death pathway by the apoptosis marker Annexin-V which showed non-significant results, while the exposure of AgCu-NP in MCF-7 cells leads to toxicity and also caused significant increase in MMP-9 level, which suggests the cell death may be associated with other pathways such as autophagy and oxidative stress related.…"

Deep aging clocks: AI-powered strategies for biological age estimation حسب Luma Srour (22254409)

"…<p>Several strategies have emerged lately in response to the rapid increase in the aging population to enhance health and life span and manage aging challenges. …"

Information Technology Disaster Recovery Plan (IT DRP) Framework – A study on IT Continuity for Smart City in Abu Dhabi Smart Government حسب AL HASSAN, LINDA KHALED MOHAMMED

"…Over the years, technology application in various fields of business has increased, with one such concept been seen in the form of smart cities. …"
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Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19 حسب Matli, Kamal

"…Background COVID-19 is a respiratory disease that results in a prothrombotic state manifesting as thrombotic, microthrombotic and thromboembolic events. As a result, several antithrombotic modalities have been implicated in the treatment of this disease. …"
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Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesen... حسب Lubna Therachiyil (4246156)

"…Our results showed that activation of AhR by TCDD in A2780 cells induced the PI3K/AKT pathway followed by induction of anti-apoptotic proteins BCL-2, BCL-xl, and MCL-1. In addition, a significant increase in stemness marker aldehyde dehydrogenase (ALDH1) was observed. …"

Microalgal-based desalination brine remediation: Achievements, challenges, and future research trends حسب Isra E. Gilani (17019066)

"…<p dir="ltr">Desalination brine discharge has several negative impacts on the marine environment, such as increase in salinity levels, effects on marine biodiversity, and alteration of the physical and chemical characteristics of water. …"

Advanced Technology in Agriculture Industry by Implementing Image Annotation Technique and Deep Learning Approach: A Review حسب Normaisharah Mamat (19517623)

"…<p dir="ltr">The implementation of intelligent technology in agriculture is seriously investigated as a way to increase agriculture production while reducing the amount of human labor. …"

Effect of Diverse Seismic Hazard Estimates on Performance and Overall Cost of RC Shear Wall Buildings in Dubai, UAE حسب Aly, Nader Essam

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The impact of COVID-19 pandemic social restrictions on individuals with autism spectrum disorder and their caregivers in the Stateof Qatar: A cross-sectional study حسب Yasser Saeed Khan (17191735)

"…Out of these, 24 (41 %) reported a clinically significant increase in their care burden. Among caregivers reporting an increase in care burden, two-third were caring for individuals whose behaviour either remained unchanged or improved during social restrictions. …"