Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration by Megan F. Duffy (5713772)

“…</p><h3>Results</h3><p dir="ltr">Intrastriatal injection of α-syn PFFs to rats resulted in widespread accumulation of phosphorylated α-syn inclusions in several areas that innervate the striatum followed by significant loss (~ 35%) of substantia nigra pars compacta dopamine neurons within 5–6 months. …”

A Multidecadal Assessment of Drought Intensification in the Middle East and North Africa: The Role of Global Warming and Rainfall Deficit by Ahmed El Kenawy (7510103)

“…For example, in comparison to the SPI, the SPEI indicated an increase of 15% in the areas affected by severe to very extreme droughts in arid regions (Aw). …”

Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study by Fahmi Othman (14777506)

“…Compared to PPCI angiograms, the non-PPCI angiograms showed a statistically significant reduction in the percentage of stenosis (71.6± 14.4% vs 64.5± 14.4%, <i>p</i>≤ 0.001), and an increase in minimal luminal diameter (0.82± 0.45 mm vs 1.00± 0.44 mm, <i>p</i>≤ 0.001) of non-culprit lesion. …”

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels by Haya Al-Sulaiti (5449256)

“…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …”

Synthesis and analysis of silver–copper alloy nanoparticles of different ratios manifest anticancer activity in breast cancer cells by Sara Al Tamimi (9692615)

“…Furthermore, we observed the cell death pathway by the apoptosis marker Annexin-V which showed non-significant results, while the exposure of AgCu-NP in MCF-7 cells leads to toxicity and also caused significant increase in MMP-9 level, which suggests the cell death may be associated with other pathways such as autophagy and oxidative stress related.…”

Deep aging clocks: AI-powered strategies for biological age estimation by Luma Srour (22254409)

“…<p>Several strategies have emerged lately in response to the rapid increase in the aging population to enhance health and life span and manage aging challenges. …”

Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19 by Matli, Kamal

“…Background COVID-19 is a respiratory disease that results in a prothrombotic state manifesting as thrombotic, microthrombotic and thromboembolic events. As a result, several antithrombotic modalities have been implicated in the treatment of this disease. …”
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Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesen... by Lubna Therachiyil (4246156)

“…Our results showed that activation of AhR by TCDD in A2780 cells induced the PI3K/AKT pathway followed by induction of anti-apoptotic proteins BCL-2, BCL-xl, and MCL-1. In addition, a significant increase in stemness marker aldehyde dehydrogenase (ALDH1) was observed. …”

Microalgal-based desalination brine remediation: Achievements, challenges, and future research trends by Isra E. Gilani (17019066)

“…<p dir="ltr">Desalination brine discharge has several negative impacts on the marine environment, such as increase in salinity levels, effects on marine biodiversity, and alteration of the physical and chemical characteristics of water. …”

Advanced Technology in Agriculture Industry by Implementing Image Annotation Technique and Deep Learning Approach: A Review by Normaisharah Mamat (19517623)

“…<p dir="ltr">The implementation of intelligent technology in agriculture is seriously investigated as a way to increase agriculture production while reducing the amount of human labor. …”

Effect of Diverse Seismic Hazard Estimates on Performance and Overall Cost of RC Shear Wall Buildings in Dubai, UAE by Aly, Nader Essam

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The impact of COVID-19 pandemic social restrictions on individuals with autism spectrum disorder and their caregivers in the Stateof Qatar: A cross-sectional study by Yasser Saeed Khan (17191735)

“…Out of these, 24 (41 %) reported a clinically significant increase in their care burden. Among caregivers reporting an increase in care burden, two-third were caring for individuals whose behaviour either remained unchanged or improved during social restrictions. …”

Road deaths and injuries in India: Action required on the five pillars of road safety by Gopalakrishna Gururaj (19807233)

“…The economic losses from road crashes are estimated to be 3% of GDP and are increasing from year to year (2). Amidst significant regional variations, many Indian states have road deaths much above the national average. …”

Hygienic quality of chlorinated city water stored in household tanks in Byblos, Lebanon. (c2004) by Abi Chedid, Najib

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A Fully Optical Laser Based System for Damage Detection and Localization in Rail Tracks Using Ultrasonic Rayleigh Waves: A Numerical and Experimental Study by Masurkar, Faeez

“…First, the noise and unwanted wave packets increase with the increase in the time window and the inspection length. …”
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Designing a Flexible and Reconfigurable Manufacturing System Considering a Circular Shaped Layout by AlDuaij, Awrad Khalid

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التطبيق العملي لتدبير ديون الميت: ماليزيا أنموذجا by Awang, Abd Bari

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The effects of Social Determinants of Health on Type 2 Diabetes Outcomes (A1C) by Awad, Nathalie

“…To explore possible mediators in this relationship, a path analysis was conducted based on a hypothetical model derived from the literature. Significant direct and indirect relationships were obtained between several risk factors (socioeconomic factors, depression, fatalism emotional distress, diabetes duration of 5-10 years, diabetes self- care activities, self-monitoring of blood glucose, diabetes medication and/or insulin therapy, quality of life, and diabetes complications) and A1C. …”
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Exercise training-induced speeding of VO₂kinetics is not intensity domain-specific or correlated with indices of exercise performance by Erin Calaine Inglis (7042334)

“…There were no PRE to POST differences for CON (p < 0.05) in any variables. Despite significant increases in maximal VO₂ (VO_2max ), estimated lactate threshold (θLT), maximal metabolic steady state (MMSS), and peak power output (PPO) for the intervention groups (p < 0.05), there were no significant correlations from PRE to MID or MID to POST between ΔτVO₂ and Δ V O_2max (r=– 0.221, r = 0.119), ΔPPO (r= – 0.112, r= – 0.017), ΔθLT (r= 0.083, r = 0.142) and ΔMMSS (r= – 0.213, r = 0.049)(p > 0.05).…”

Optimum sustainable utilisation of the whole fruit of Jatropha curcas: An energy, water and food nexus approach by Mohammad Alherbawi (14155767)

“…In this context, biomass has increased in popularity and acquired a significant share of the global energy mix in a relatively short time. …”