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81
Long-Chain Acyl-CoA Synthetase 1 Role in Sepsis and Immunity: Perspectives From a Parallel Review of Public Transcriptome Datasets and of the Literature
منشور في 2019"…Furthermore, available clinical data indicate that levels of ACSL1 and ACSL4 induction was significantly higher in fatal cases of sepsis. This denotes potential translational relevance and is consistent with involvement in pathways driving potentially deleterious systemic inflammation. …"
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82
Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
منشور في 2021"…Dietary OTA at all the tested levels induced the hepatic and renal tissue injury as indicated by significant decreased total antioxidant capacity in these organs along with significant decreased (p ≤ 0.05) serum concentrations of total proteins and albumin. …"
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83
Experimental investigations on the performance of a thermo-mechanical refrigeration system utilizing ultra-low temperature waste heat sources
منشور في 2023"…<p>Experimental studies that investigate the utilization of ultra-low temperature (between 48 °C and 120 °C) waste heat, which forms 25 % of the global unrecovered waste heat, to drive thermal cooling systems are rare. Thus, this study fills a significant gap in the literature by (i) experimentally evaluating the performance of a new full-scale thermo-mechanical refrigeration (TMR) system at ultra-low temperatures ranging from 50 °C to 85 °C, (ii) characterizing its operation with different commercial refrigerants, and (iii) identifying optimal operating conditions and working fluids for the investigated TMR system. …"
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84
Akkermansia, a Possible Microbial Marker for Poor Glycemic Control in Qataris Children Consuming Arabic Diet—A Pilot Study on Pediatric T1DM in Qatar
منشور في 2021"…The results have revealed that the subjects who had undergone CSII therapy had increased microbial diversity and genus <i>Akkermansia</i> was significantly enriched in the subjects without CSII therapy. …"
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85
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase
منشور في 2022"…Expression of cancer stem cell markers (CD133, CD44, ganglioside GD2) was significantly increased in A375 spheres, as detected by flow cytometry. …"
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86
Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi...
منشور في 2011"…Macrophages from ApoE⁻′⁻/TG-BM chimeric mice express reduced levels of PPARγ₁, LXRα, ATP-binding cassette A₁ (ABCA₁) and ATP-binding cassette G₁ (ABCG₁) and increased levels of the inflammatory mediators interleukin (IL)-6 and tumor necrosis factor (TNF)-α compared with macrophages of control chimeric mice (ApoE⁻′⁻/NT-BM) that received AEBP₁ nontransgenic (AEBP₁ᴺᵀ) BM cells. …"
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87
Downregulation of <i>CYP17A1</i> by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties
منشور في 2022"…Conclusion: In the short term, 20-hydroxyecdysone mediates CYP17A1 downregulation without a significant increase in plasma progesterone, which has a vasodilatory effect involving inhibition of voltage-dependent calcium channels, and the potential to enhance 20-hydroxyecdysone vasorelaxation.…"
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88
Follow‐Up and Comparative Assessment of SARS‐CoV‐2 IgA, IgG, Neutralizing, and Total Antibody Responses After BNT162b2 or mRNA‐1273 Heterologous Booster Vaccination
منشور في 2024"…Nevertheless, a heterologous booster led to an increase of ~12 times in the immune response when compared to two consecutive homologous ChAdOx1 immunizations. …"
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89
Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
منشور في 2018"…Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …"
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90
Myxedema psychosis A protocol for a systematic review and a pooled analysis
منشور في 2020"…<h3>Background</h3><p dir="ltr">Myxedema psychosis (MP) is a rare presentation of hypothyroidism. Although known for >70 years, a significant lack of systematic literature describing this condition exists. …"
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91
Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
منشور في 2021"…Having an elevated HbA1c level significantly increases the risk of developing diabetes-related health complications. …"
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92
Adsorption as a Process for Produced Water Treatment: A Review
منشور في 2020"…<p dir="ltr">Produced water (PW) is a by-product of oil and gas operations, and its production is foreseen to increase in the upcoming years. …"
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93
Organizational Change Management: A study on the need for a re-structured organization within a functional configuration
منشور في 2009"…It will also be concluded that in a functional organization, the introduction of projectized structure for the newly introduced organization may significantly increase the probability of successful outcome from projects.…"
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94
A young patient with Graves' disease presenting with a triad of heart failure, pancytopenia, and jaundice: A case report
منشور في 2024"…On examination, he had jaundice, bilateral exophthalmos, diffuse goiter, ascites, and significant lower limb edema. Laboratory investigations showed increased Thyroxin level with a suppressed thyroid stimulating hormone and positive anti‐thyrotropin receptor antibodies. …"
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95
Teaching the novel in a university english as a foreign language (EFL) context
منشور في 2016"…The aim of the present study is to explore the preliminary  effect of selected novels combined with film and student oral presentations on L1 Arabic EFL learners  use of vocabulary in one 20th Century American Novel course at an English medium university in Lebanon. Two literary essay tests were administered to 25 students, one at the beginning and another at the end of the semester, holistically scored and qualitatively analyzed for vocabulary variety. Main findings indicated that although the holistic scores did not significantly increase, there was use of a more diverse and use of vocabulary on Test 2. Recommendations are made for classroom practice and future research.…"
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96
Toward a Clearer Understanding of Value‐Based Healthcare: A Concept Analysis
منشور في 2025"…<h3>Background</h3><p dir="ltr"> Value‐based healthcare (VBHC) aims to improve the quality of healthcare delivery while reducing costs and also aims for outcomes that are of utmost importance from patients’ perspectives. Despite a growing interest in VBHC, a significant knowledge gap persists within the existing literature in the absence of a clear conceptualization of VBHC itself.…"
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97
Managing change process: A case study of a private school in Sharjah
منشور في 2016"…The significance of change process management increases as the modern world trends of education and learning require a change. …"
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98
Designing a Flexible and Reconfigurable Manufacturing System Considering a Circular Shaped Layout
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99
A Design Study for Multivariable Feedback Control For a Variable Speed Wind Turbine
منشور في 2017"…Consequently, the demand for utilizing renewable clean energy arises. Wind energy is a significant source of energy since it is clean, renewable, and cost effective in comparison with other renewable resources like photovoltaic which has higher costs in production and maintenance. …"
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100
A customised fetal growth and birthweight standard for Qatar: a population-based cohort study
منشور في 2024"…The main pathological factors were preexisting diabetes (increase by +175.7 g) and smoking (decrease by −190.9 g). …"