Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy حسب Samson Mathews Samuel (18808246)

"…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …"

Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar حسب Lolwa Al Ansari (18466227)

"…The proportion of patients spending less than 8 hours in the OB ED observation beds rose from 74% in January 2022 to over 98% in 2023. Notably, there was a remarkable decrease in patients who Left Without Being Seen (LWBS) and in absconded patient rates from 2020 to 2023 (Figure 2).…"

Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties حسب Al Zaabi, Alanood

"…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …"
احصل على النص الكامل

Association of dyslipidemia, diabetes and metabolic syndrome with serum ferritin levels: a middle eastern population-based cross-sectional study حسب Neyla S. Al Akl (15189997)

"…The OR for MetS also increased significantly across the Sfer Quartiles from OR: 1 in Q1 to 1.92 (1.06–3.02) in Q4 for women and to 2.07 (1.08–3.98) in Q4 in men. …"

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

"…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …"

Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts حسب Amr A. Fadle (14150298)

"…Both double and triple arthrodesis groups had a statistically significant improvement of the mean AOFAS hindfoot score post-operatively (71.46 ± 7.77 vs. 88.38 ± 3.66, p < 0.001) and (66.9 ± 7.69 vs. 85 ± 5.83, p < 0.001), respectively. …"

Advanced direct air capture of CO₂ using air conditioning systems: a life cycle assessment حسب Namra Mir (17017734)

"…The integrated system exhibits significantly reduced environmental impacts compared to a standalone DAC unit. …"

Intracoronary pharmacological therapy versus aspiration thrombectomy in STEMI (IPAT-STEMI): A systematic review and meta-analysis of randomized trials حسب Rasha Kaddoura (12506936)

"…Thrombolytics significantly reduced major adverse cardiovascular events (MACE) (odds ratio = 0.29, 95% CI: 0.13–0.65) without increasing bleeding risk. …"

Economic Statistical Design Of (X)Over-Bar Control Charts For Systems With Gamma(Lambda, 2) In-Control Times حسب Al-Oraini, H.A.

"…The study shows that the statistical performance of control charts can be improved significantly, with only a slight increase in the cost, by adding constraints to the optimization problem. …"
احصل على النص الكامل

Economic Statistical Design Of (X)Over-Bar Control Charts For Systems With Gamma (Lambda,2) In-Control Times حسب Al-Oraini, H.A.

"…The study shows that the statistical performance of control charts can be improved significantly, with only a slight increase in the cost, by adding constraints to the optimization problem. …"
احصل على النص الكامل

Potentially inappropriate medications use in community-based aged patients: a cross-sectional study using 2012 Beers criteria حسب Kuyumjian, Yara-Mary

"…The factors associated with PIMs use were age, osteoporosis, Alzheimer/dementia, diabetes, and alcohol consumption. PIMs use increased significantly between Beers criteria 2003 and 2012 (Chi-squared test, P<0.001; McNemar’s test, P<0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Long-term survival (>78 days) was observed in 80% of mice with established intracerebral syngeneic melanoma treated with 40 mg/kg of WP1066 in contrast to control mice who survived for a median of 15 days. Although WP1066 did not induce immunological memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (TGF-β, RANTES, MCP-1, VEGF), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27–Driven Itch Pathway حسب Yanqing, Li

"…Intradermal IL-27 injection failed to directly induce itch in mice but upregulated skin protease-activated receptor 2 (PAR2) transcripts, a key factor in itch and AD. IL-27 activated human keratinocytes, increasing PAR2 transcription and activity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Enhancing human thermal comfort in hot arid cities: A systematic review of urban heat island observations and mitigation strategies حسب Omer Abedrabboh (17346847)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Building and Environment<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.buildenv.2025.113398" target="_blank">https://dx.doi.org/10.1016/j.buildenv.2025.113398</a></p>…"

Knowledge and Anxiety about COVID-19 in the State of Qatar, and the Middle East and North Africa Region—A Cross Sectional Study حسب Sathyanarayanan Doraiswamy (4091776)

"…Knowledge about COVID-19 was significantly different across the two survey populations, with a much higher proportion of healthcare workers possessing better COVID-19 knowledge than the general public (62.9% vs. 30.0%, p < 0.0001). …"

COVID-19 mothers’ mother–baby bonding, feeding practices, postnatal care experiences in Qatar: A mixed-methods approach حسب laura Moya falcon (22556218)

"…</p><h3>Conclusions</h3><p dir="ltr">The pandemic has significantly impacted maternal–infant bonding, as evidenced by increased reports of maternal stress, reduced physical contact, and limitations on partner support. …"

The effectiveness of Brain Gym® Exercises on Improving Students’ Performance in classes of middle school boys in private schools in Dubai, UAE(Ethnographic Study Conducted at the A... حسب AL HERBAWI, DUA’A

"…On the academic level, the marks of post-implemented quizzes showed a significant drop, however, post-implemented major exams showed a significant rise. …"
احصل على النص الكامل

Metabolomic Profiling of Pregnancies With Polycystic Ovary Syndrome Identifies a Unique Metabolic Signature and Potential Predictive Biomarkers of Low Birth Weight حسب Ilhame Diboun (3522413)

"…Regression models indicated significant increases in the triglycerides C20:4_C34:3 and C18:2_C38:6 in the PCOS group [false discovery rate (FDR) <0.05]. …"

Evaluating the Effectiveness of a Behavioural Training Programme for Primary School Teachers in Al Dhafra Private Schools to Modify the Behaviour of Students With ASD حسب SHARAFEDDIN, ETAB

"…The quantitative results revealed a significant positive impact of the training programme, with 92.0% of the teachers reporting improved knowledge and 91.4% exhibiting more positive attitudes towards students with ASD. …"
احصل على النص الكامل

Beyond the needle: How nonsurgical management transforms foot and ankle ability in male footballers with posterior ankle impingement- a longitudinal study حسب Gupta, Jyoti

"…Tenderness and ROM showed significant changes after 4 and 8 weeks. The FAAM% score significantly increased (p < 0.001) after 8 weeks, reflecting enhanced overall functional ability. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل