Data Sheet 1_Effects of drospirenone and ethinylestradiol tablets (II) combined with metformin on the composition of gut microbiota in polycystic ovary syndrome with insulin resist... by Yanglu Liu (22417861)

“…After treatment, CHO levels decreased in PCOS-NIR group (P < 0.05); FINS, LDL-C and HOMA-IR decreased and HDL-C levels increased in PCOS-IR group (P < 0.05). 2. …”

Table 1_The prevalence and correlates of falls in adults with attention-deficit/hyperactivity disorder: cross-sectional study.docx by Maraheb M. Alkhalidi (22389535)

“…Studies have shown that individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) have decreased balance. Poor balance is associated with increased risk of falls. …”

Data Sheet 1_Tcirg1 deficiency delays osteoarthritis progression by impairing lysosome acidification and peripheral accumulation in osteoclasts.docx by Rui Sun (177521)

“…Tcirg1 deficiency in knockout mice delayed OA progression, as evidenced by reduced cartilage damage, improved subchondral bone mass, and decreased osteoclast activity. In vitro, Tcirg1 expression increased during osteoclast differentiation, and its knockdown inhibited osteoclast fusion and bone resorption by impairing lysosome acidification and peripheral accumulation.…”

DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Upregulation of DYNLT3 expression markedly decreased the expression of Wnt signaling pathway-related proteins (Dvl2, Dvl3, p-LRP6, Wnt3a, Wnt5a/b, Naked1, Naked2, β-catenin and C-Myc) and EMT-related proteins (N-cadherin, SOX2, OCT4, vimentin and Snail), and increased the expression of E-cadherin and Axin1. …”

DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Upregulation of DYNLT3 expression markedly decreased the expression of Wnt signaling pathway-related proteins (Dvl2, Dvl3, p-LRP6, Wnt3a, Wnt5a/b, Naked1, Naked2, β-catenin and C-Myc) and EMT-related proteins (N-cadherin, SOX2, OCT4, vimentin and Snail), and increased the expression of E-cadherin and Axin1. …”

Supplementary file 1_Investigating the feasibility of machine learning to guide personalized red blood cell (RBC) transfusion: analyzing the heterogeneity of RBC transfusion in sep... by Penglei Yang (8090156)

“…The Kaplan-Meier curves and the log-rank test demonstrated that the RBC transfusion decreased the survival of patients in Quantile1 (p < 0.001) and Quantile2 (p = 0.011) but increased the survival of patients in Quantile4 (p < 0.001).…”

Table 1_Detailed understanding of reduced geoeffectiveness of solar cycle 24 in association with geomagnetic storms.xlsx by R. Selvakumaran (21290378)

“…<p>Solar Cycle 24, the weakest in over a century, exhibited significant deviations from previous cycles, beginning with a prolonged minimum, weak polar fields, and asynchronous polar field reversal, leading to hemispheric asymmetry. …”

<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …”

Table1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.xlsx by Yunxia Zhang (30848)

“…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. …”

DataSheet2_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.pdf by Yunxia Zhang (30848)

“…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. …”

DataSheet1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.docx by Yunxia Zhang (30848)

“…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. …”

Supplementary Material for: Bidirectional Impact of Varying Severity of Acute Kidney Injury on Calcium Oxalate Stone Formation by Yang Y. (3237684)

“…Conclusion: Inadequate repair of tubular epithelial cells after severe AKI increases the risk of kidney stone formation, with the upregulation of inflammation-related genes regulated by PKNOX1 playing a role in this process. …”

Data Sheet 1_Mitigating ammonium and nitrate leaching in rice-wheat crop rotation: efficacy of neem coated urea and compost co-application.pdf by Sandeep Kumar (145759)

“…Application of 125%-N significantly increased the total mineral N leaching. …”

Image 1_Assessment of microstructural abnormalities in gray and white matter of minimal hepatic encephalopathy patients using diffusion kurtosis imaging and their associations with... by Qing Sun (492552)

“…</p>Results<p>The TBSS analysis results showed that MHE patients had significantly decreased fractional anisotropy (FA) in the temporal part of the left superior longitudinal fasciculus and decreased kurtosis fractional anisotropy (KFA) in the left corticospinal tract and anterior thalamic radiation (p < 0.05, threshold-free cluster enhancement corrected). …”

Data Sheet 1_HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1.pdf by Keita Tanigaki (13162449)

“…In HAX1-knockdown IHGE cells, significantly decreased levels of JAM1 were found. Additionally, cisplatin, a chemotherapeutic agent reported to inhibit HAX1, also led to decreased expression of both HAX1 and JAM1. …”

Deletion of glycosyltransferase <i>galE</i> impairs the InlB anchoring and pathogenicity of <i>Listeria monocytogenes</i> by Xiaowei Fang (696967)

“…In this study, we deleted the <i>galE</i> gene, which is involved in galactosylation, from <i>L. monocytogenes</i> strain ScottA. We found that <i>galE</i> deletion reduced InlB anchoring, weakened bacterial adhesion and invasion of Caco-2 cells (human colorectal adenocarcinoma cells) and MGC803 cells (human gastric carcinoma cells), increased phagocytosis but decreased proliferation in RAW264.7 cells (mouse mononuclear macrophage leukaemia cells), and decreased bacteria load, mortality, and tissue damage in infected mice. …”

Supplementary Material for: Association of Two Neonatal Encephalopathy Scores with Neurophysiology in Newborns with Suspected Hypoxic Ischemic Encephalopathy by figshare admin karger (2628495)

“…Results: There was a significant association between both NE scores and aEEG/cEEG (p<0.001), with higher scores in newborns with more abnormal aEEG background patterns. …”

Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x... by Yuanling Yang (22524785)

“…In contrast, 400 μM MT treatment effectively mitigated oxidative damage by coordinated activation of superoxide dismutase (SOD,+14.3%), peroxidase (POD,+21.7%), and catalase (CAT,+11.7%) activities, thereby stabilizing membrane integrity. Furthermore, MT significantly alleviated photoinhibition: F_V/F_M increased by 39%, Y_II and qP rose, and NPQ decreased compared to salt-stressed plants, reflecting enhanced protection of the PSII reaction center and optimized light energy allocation. …”

Paiva et al. data by Sergio Nogueira-Filho (10808859)

“…Specifically, haemoglobin concentration decreased 24 hours after ozone therapy, MCHC levels increased seven days post-ozone therapy, and serum AST activity decreased seven days post-ozone therapy. …”

Data Sheet 1_Global soil moisture dynamics: attribution of contributions and their association with GPP.docx by Yang Li (7082)

“…This study further integrates the MODIS MCD12C1 and GOSIF GPP datasets to explore the correlation between SM and GPP on a global scale. The results indicate that between 2000 and 2024, global Total Soil Moisture (TSM) shows a marked declining trend, with SM decreasing synchronously across all seasons. …”