Data Sheet 1_Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis.pdf حسب Yanyan Zhu (32035)

"…Importantly, patients with high TRA16 expression demonstrated elevated TMB and decreased stromal and immune features.</p>Discussion<p>These findings highlight TRA16 as a potential master regulator of oncogenic processes, contributing to tumor progression through coordinated regulation of cell cycle genes, intercellular signaling, and genomic instability. …"

ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer حسب Ana García-García (17779885)

"…Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease, marked by a survival rate of only 12%. …"

Image 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.jpeg حسب Shuangmei Zhang (1807303)

"…</p>Results<p>By week 24, secukinumab treatment led to significant reductions in disease severity scores (QMG: 60.7%; MG-QOL15: 58.3%; MG-ADL: 64.1%) and AChR antibody levels (69.23%). …"

Table 1_Emergency department utilization among youth in foster care: benefits of a patient-centered medical home.pdf حسب Nicholas Szoko (11260475)

"…The patient-centered medical home (PCMH) offers a potential model to reduce overutilization of healthcare resources. …"

Docetaxel and quercetin-loaded lipid nanocarrier optimized by quality by design for glioblastoma therapy: a ligand-conjugated and therapeutic repurposing approach حسب Zufika Qamar (22259678)

"…Compared to non-conjugated NLC and (DTX-QUR) suspension (SUS), Tf-(DTX-QUR) NLC showed 3.6- and 5.8-fold decrease in IC₅₀, respectively. Cellular uptake studies demonstrated significantly (<i>***p < 0.001</i>) high internalization of Tf-conjugated NLC to U87-MG cells. …"

Supplemental Figures حسب Danielle A. Jeffrey (21187329)

"…FXR1 has seven isoforms, including isoforms mostly expressed in skeletal and cardiac tissue, and play a significant role in heart development and function. …"

Data_Sheet_2_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF حسب Meng Chen (48769)

"…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …"

Data_Sheet_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF حسب Meng Chen (48769)

"…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …"

Table 2_Quantitative evaluation of IVL: based on the tunica media gypsum calcification model and a prospective animal study.doc حسب Zongwei Liu (3133743)

Table 1_Quantitative evaluation of IVL: based on the tunica media gypsum calcification model and a prospective animal study.doc حسب Zongwei Liu (3133743)

Data Sheet 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf حسب Yi Shen (152956)

"…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …"

Data Sheet 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf حسب Yi Shen (152956)

"…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …"

Data Sheet 1_What should we focus on in pregnancy complicated by pheochromocytoma? a bibliometric analysis (1990-2024).pdf حسب Shiyun Deng (21734750)

"…Purpose of review<p>The incidence of pheochromocytoma and paraganglioma (PPGL) in pregnancy is extremely low, yet it poses a significant threat to maternal and fetal safety. …"

Supplementary file 1_Indirect regeneration of long-term callus cultures in gladiolus: a protocol for stable genetic fidelity.docx حسب Seyedehraziyeh Mousavimatin (21398525)

"…This medium led to an 80% decrease in the accumulation of phenolic compounds across all cultivars in comparison to the control. …"

Blood chemistry test results. حسب Maria A. Colombatti Olivieri (21362615)

"…Red and blue dashed line shows the limit of a significant increase or decrease in the value of the analyte in blood. …"

Analysis of biases in amplicon coverage across samples sequenced with diverse Ampliseq-based protocols (DDD/IDI/III – corresponds to variations of PCR mix1 (I/D), ligase/buffer (I/... حسب P.A. Shatalov (21485215)

"…<p><b>(A)</b> – heatmap of amplicon coverage (% of average coverage) across samples demonstrates significant variation in per-sample set of dropped out (10% of average sample coverage) amplicons depending on <b>i)</b> PCR mix 2 used <b>ii)</b> Digest Mix used. …"

Table 1_Correlation between CBC-derived inflammatory indicators and all-cause mortality with rheumatoid arthritis: a population-based study.docx حسب Yu Liu (6938)

"…The Kaplan-Meier analysis indicated a significant decrease in the survival probability among individuals with elevated SIRI, NLR, and MLR levels. …"

Burden trends and risk factors for prostate cancer from 1990 to 2021: a systematic analysis of the Global Burden of Disease Study 2021 حسب Yuan Xu (161775)

"…PCa was more common in regions with a high SDI. Mortality was the highest in regions with a low SDI. …"

Data Sheet 1_Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine.docx حسب Jingang Zhao (20416198)

"…The viral load results demonstrated that the vaccine group significantly reduced viral copy numbers in serum and effectively decreased the concentration of the inflammatory cytokine IL-1β. …"

Data associated with 'Does Platycnemia Develop in Squatting Populations as a Response to Torsional Rotation Across the Subadult Growth Plate?' manuscript. حسب Samantha Magrini (22208212)

"…</p><p dir="ltr"><b>Results</b>: Our results show that cnemic index significantly decreases as the tibia lengthens, resulting in increasing mediolateral flattening and greater instances of platycnemia. …"