Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

“…A subseries of these molecules displays cellular inhibition of Ras–Raf binding, as well as decreased phosphorylation of the downstream protein ERK, demonstrating that potent multivariant Ras inhibitors can be accessed from this novel pocket.…”

Gating strategy of experiment using 30 min EdU pulses experiments in mOr2-Piwi1 juvenile polyps. by Eudald Pascual-Carreras (12115380)

A) RT-qPCR analysis of <i>Yap</i>, <i>Taz</i>, and <i>Tead2</i> shows a significant decrease in transcript levels over postnatal stages from P0 to P28. by Heather L. Dingwall (14573796)

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

(a) M-K test of annual average water level in Caspian Sea (unformatted fit (UF) and underidentification bias (UB) is positive and reverse order in the time series respectively; ɑ i... by Zihao Duan (17403792)

Summary of sites of activity of genes encoded by SNPs observed to be associated in our study in the NO signaling pathway downstream of Cit. by Dai Nogimura (21445649)

Subjects:

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

Charts revealing A) the significant decrease (<i>p</i> < 0.05) in the membrane integrity and B) the significant increase (<i>p</i> < 0.05) in the membrane permeability after treatment with harmalacidine hydrochloride in a representative <i>S. aureus</i> isolate (n = 3 as technical repeats of the same isolate). by Manal A. Alossaimi (10269852)

“…<p>Charts revealing A) the significant decrease (<i>p</i> < 0.05) in the membrane integrity and B) the significant increase (<i>p</i> < 0.05) in the membrane permeability after treatment with harmalacidine hydrochloride in a representative <i>S. aureus</i> isolate (n = 3 as technical repeats of the same isolate).…”

One-Step Synthesis of a Novel Intrinsically Flame-Retardant Thermoplastic Polyamide 6 Elastomer: Structure, Properties, and Spinnability by Haoyi Hu (18980061)

“…Despite great advances in thermoplastic polyamide elastomers (TPAEs), it is still a significant challenge for preparing flame-retardant TPAEs with facile strategies. …”

Proportion of counties that experience, on average, a decrease in salinity levels during El Niño years, divided by geographical areas. by Nicola Limodio (15138316)

General linear mixed model coefficients and significance for species-specific ungulate intensity of use as a function of cattle grazing period. by Kathryn Knodel (20036529)

Does a correlation exist between delayed vaccination and a decreased vaccine confidence? by Virginia Reverte (9046494)

“…Online questionnaire was sent to their parents, followed by a telephone questionnaire for non-responders. Regarding MMR first dose, a significant association was found between delay and birth order and intellectual/motor delay of children. …”

Stepped wedge cluster randomized trial design. by Antonio Marty Quispe (12574259)

“…Analysis followed a stepped-wedge mixed-effects negative binomial model adjusting for clustering and time trends. …”

Ni causes a decrease in membrane sterols in A549 lung epithelial cells. by Amber R. Matha (19681603)

ActAs and CoT prompt strategies do not result in decreased error rate for tasks with increasing complexity. by Jacqueline A. Jansen (14894276)

Self-correction prompt strategy results in decreased error rate for all tasks with increasing complexity. by Jacqueline A. Jansen (14894276)

fileCont prompt strategy results in decreased error rate for some tasks with increasing complexity. by Jacqueline A. Jansen (14894276)

General procedure for the synthesis of B. by Xueqin lu (22250795)

TH5487 decreases RSV replication in lungs. by Lang Pan (5145221)

HSP90 inhibition by RGRN-305 decreased the gene expression of proinflammatory cytokines induced by SARS-CoV-2 S protein. by Hakim Ben Abdallah (14578241)