يعرض 20,701 - 20,720 نتائج من 21,342 نتيجة بحث عن '(( significant advancement decrease ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.30s تنقيح النتائج
  1. 20701

    Table 7_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx حسب Linling Du (22827035)

    منشور في 2025
    "…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
  2. 20702

    pH sensitive lipid polymeric hybrid nanoparticle (LPHNP) of paclitaxel and curcumin for targeted delivery in breast cancer حسب Hrishikesh Sarma (14827761)

    منشور في 2024
    "…MTT-assay studies revealed enhanced cytotoxicity of CUR and PTX as LPHNPs showing IC<sub>50</sub> value of free CUR & PTX 480.06 µg/mL decreasing to 282.97 µg/mL for CS-CUR-PTX-LPHNPs. <i>In vivo</i> pharmacokinetic evaluations in rats confirmed significantly improved bioavailability, with a 3.8-fold increase in AUC for CUR and a 6.6-fold increase for PTX. …"
  3. 20703

    Spectral shift of fluorophore NHS-esters. حسب Hyunwoo Kim (690467)

    منشور في 2025
    "…After 5 min of illumination with a 561-nm excitation laser, the fluorescence signal in the 647-nm detection channel decreased, while the signal in the 561-nm detection channel significantly increased, indicating a spectral blue-shift of the emission spectrum. …"
  4. 20704

    Data Sheet 2_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip حسب Fengli Ye (22123540)

    منشور في 2025
    "…Machine learning identified four hub genes—LEF1, ITGAX, BLVRB, and ATF4. All were significantly upregulated in ICH tissues and plasma, correlating with immune cell infiltration. …"
  5. 20705

    Image 2_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif حسب Linling Du (22827035)

    منشور في 2025
    "…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
  6. 20706

    Movie 2 Rik<sup>null</sup> vs. WT. حسب Erdyni N. Tsitsikov (20384719)

    منشور في 2024
    "…Histological examination of anterior thalamic nuclei demonstrated decreased myelination of anteroventral nuclei but not of anterodorsal nuclei in P23 <i>Rik</i><sup><i>null</i></sup> mice. …"
  7. 20707

    Supplementary file 2_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx حسب Wenjing Ji (720509)

    منشور في 2025
    "…Introduction<p>Approximately one-third of the world’s children have elevated blood lead levels (BLLs), which may lead to often-irreversible decreased intelligence, behavioral difficulties, and learning problems. …"
  8. 20708

    Data Sheet 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf حسب Sadia Hamera (22524803)

    منشور في 2025
    "…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"
  9. 20709

    Table 2_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

    منشور في 2025
    "…This approach revealed substantial Baltic genetic components in early Slavic populations (57% in Slovakia/Slovenia) decreasing to 39%–51% in medieval Croatian samples. …"
  10. 20710

    Data Sheet 1_A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure.docx حسب Ambrish Kumar (558337)

    منشور في 2025
    "…NMEG-CGRP administration significantly attenuated these TAC-induced adverse cardiac effects in the HF mice.…"
  11. 20711

    Data Sheet 4_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf حسب Sadia Hamera (22524803)

    منشور في 2025
    "…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"
  12. 20712

    Primers used in RT-qPCR. حسب Changwen Ning (15071847)

    منشور في 2025
    "…Additionally, LBH589 significantly decreased mitochondrial reactive oxygen species (mtROS) and oxidized mitochondrial DNA (Ox-mtDNA), key triggers of inflammasome activation. …"
  13. 20713

    DataSheet1_NK cells contribute to the resolution of experimental malaria-associated acute respiratory distress syndrome after antimalarial treatment.docx حسب Emilie Pollenus (10147748)

    منشور في 2024
    "…In contrast, NK cells were crucial in the initiation of resolution upon antimalarial treatment, as survival was significantly decreased in the absence of NK cells. Considerably increased IL-10 expression by NK cells suggested an anti-inflammatory and pro-resolving phenotype. …"
  14. 20714

    Data Sheet 1_Fast perceptual learning induces location-specific facilitation and suppression at early stages of visual cortical processing.docx حسب Yajie Wang (184298)

    منشور في 2025
    "…<p>Tens of minutes of training can significantly improve visual discriminability of human adults, and this fast perceptual learning (PL) effect is usually specific to the trained location, with little transfer to untrained locations. …"
  15. 20715

    <b>The Bacterial OMP Amyloids Modulate</b><b> </b><b>α</b><b>-Synuclein and Amyloid-</b><b>β</b><b> </b><b>Aggregation</b> حسب Maksim Sulatsky (21562922)

    منشور في 2025
    "…In contrast, amyloid-β fibrils showed more extensive structural changes, with modifications to both the "fuzzy coat" and β-sheet core, accompanied by decreased clustering tendency and significantly reduced toxicity for mammalian neuroblastoma and epithelial adenocarcinoma cell lines. …"
  16. 20716

    SPSS data. حسب Myriam El Khoury-Malhame (14185996)

    منشور في 2025
    "…</p><p>Conclusion</p><p>Stigma remains a pervasive condition closely related to increased psychological suffering, decreased self-esteem and lower tendencies to seek help. …"
  17. 20717

    <b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian... حسب Silvia Torchio (611349)

    منشور في 2025
    "…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. Moreover, they exhibited dysregulated Ca<sup>2+</sup> fluxes due to altered transcription of Ca<sup>2+</sup>-related genes, including <i>CACNA1D</i>, and significantly reduced <i>SNAP25</i> levels, leading to uncoordinated oscillations and poor glucose responsiveness. …"
  18. 20718

    Data Sheet 1_Preoperative remote consultation for a green bariatric surgery: can telemedicine be safe for patients and sustainable for the environment?.pdf حسب Luigi Eduardo Conte (21669149)

    منشور في 2025
    "…At one-year follow-up, the mean BMI decreased to 29 kg/m<sup>2</sup> (±3). In the revisional surgery group, percent excess weight loss reached 75.4% at one year.…"
  19. 20719

    Table 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf حسب Sadia Hamera (22524803)

    منشور في 2025
    "…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"
  20. 20720

    Data Sheet 1_Silica nanoparticles alleviate cadmium toxicity to Pisum sativum L. seedling growth by remodeling carbon-nitrogen metabolism.docx حسب Xiaohuan Yang (3697462)

    منشور في 2025
    "…<p>The increasing incidence of soil cadmium (Cd) pollution significantly hinders the sustainable development of agriculture and food security. …"