Data Sheet 1_Disproportionate impact of the COVID-19 pandemic on socially vulnerable communities: the case of Jane and Finch in Toronto, Ontario.docx by Zahra Movahedi Nia (9238798)

“…The number of patients during the COVID-19 pandemic versus before that decreased significantly more for pop-smear tests (p = 0.041) and surgery waitlists (p = 0.037) for the Jane and Finch community.…”

<b>Metabolic Perturbations and Ectopic Fat Deposition in Low Birthweight Subjects</b><b>– Effects of a 4 Week Carbohydrate Overfeeding Challenge</b> by Charlotte Brøns (261017)

“…Subcutaneous adipose tissue (SAT) density was lower in LBW subjects and decreased during COF in both groups. Serum alanine, phosphatidylcholines, and triglycerides increased significantly more in LBW subjects during COF. …”

Figure 3 from A Proteomic Signature for Human Papillomavirus–Associated Oropharyngeal Squamous Cell Carcinoma Predicts Patients at High Risk of Recurrence by Christopher C. Jackson (21027397)

“…Axes show FC > 1.5 and adjusted <i>P</i> value (adj. P Val) < 0.01. Significantly DAPeps are indicated in red (increased in R) or blue color (decreased in R). …”

<b>Chemical components, emission dynamics, and external immune functions of red palm weevil larval volatiles in response to changes in developmental stages and pathogen stress</b> by Can-Hui Ding (22140753)

“…Furthermore, pathogen stress induced distinct volatile profiles: phenylacetaldehyde unidirectionally decreased, whereas <i>n</i>-nonanol, 4-ethylguaiacol, 2-phenylethanol, hexanal, and benzophenone levels increased. …”

Data Sheet 1_Integrated transcriptome and co-expression network analysis revealed the molecular mechanism of cold tolerance in japonica rice at booting stage.zip by Jiaqi Wang (369548)

“…</p>Results<p>The results demonstrated that cold stress significantly decreased yield traits, particularly seed-setting rate—a reliable cold tolerance indicator. …”

Effect of inhibitors on model parameters as inferred by SBI. by Johannes C. J. Heyn (21567894)

“…(a) Latrunculin A significantly decreases the actin network extension rate V_e⁰ for both MDA-MB-231 and MCF-10A cells while leaving all other parameters unchanged. …”

ZIKV infection enriches the HLA Class I pathway in brain tumour cells. by Matt Sherwood (22530221)

“…Normalised enrichment score (NES) denotes the degree to which the enrichment increased (+) or decreased (-). GSEA analysis significance is defined by p ≤ 0.05 and FDR ≤ 0.25. …”

The expression of PAX7 and MYOD1 correlate with differential expression of diverse chemokines in HuMuSC. by Katharine Striedinger (15503387)

“…Using linear regression PAX7 slope varies significantly p = 0.0001 and MYOD1 slope also varies significantly p = 0.05 n = 3 <b>(b)</b> Heat map displaying the expression levels of all cytokine protein detected in HuMuSC from collection as they activate progressively at day 0, day 3 and day 6 <i>in vitro</i>, using the high throughput proteomic Multiplex assay. …”

DataSheet1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.pdf by Seungchan An (6256061)

“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”

Table1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.xlsx by Seungchan An (6256061)

“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”

Table 1_Engineered miR-214 enriched Schwann cell-derived extracellular vesicles amplify therapeutic efficacy for peripheral neuropathy in T2D mice.docx by Lei Wang (6656)

“…Furthermore, 214-EVs markedly suppressed neuroinflammation by decreasing CD68 + macrophages and inactivating the TLR4/NF-κB signaling pathway. …”

Data Sheet 1_Impact of SARS-CoV-2 vaccination and of seasonal variations on the innate immune inflammatory response.pdf by Hend Jarras (13138641)

“…</p>Results<p>Our results show that IL-8 production after stimulation decreased after vaccination. In addition, the IL-8 response was significantly different depending on the season when the visit occurred, for both COVID-19 vaccinated and unvaccinated individuals.…”

Image 3_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx by Xin Yu (124814)

“…Cellular experiments using A549 and Beas2B cells showed that PIN significantly reduced TGF-β1-induced mesenchymal marker expression while increasing epithelial marker expression. …”

Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Unraveling Microplastic Effects on Gut Microbiota across Various Animals Using Machine Learning by Lingzi Yin (20477620)

“…Microplastics, rapidly expanding and durable pollutant, have been shown to significantly impact gut microbiota across a spectrum of animal species. …”

Image 4_Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy.tiff by Tyler C. Hillman (13030476)

“…MAP2 expression was significantly decreased (p < 0.05) between 1.5–6.0 mm of the brain compared to Saline-Hypoxia and Naïve animals. …”

Image 5_Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy.tiff by Tyler C. Hillman (13030476)

“…MAP2 expression was significantly decreased (p < 0.05) between 1.5–6.0 mm of the brain compared to Saline-Hypoxia and Naïve animals. …”

Image 11_Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy.tiff by Tyler C. Hillman (13030476)

“…MAP2 expression was significantly decreased (p < 0.05) between 1.5–6.0 mm of the brain compared to Saline-Hypoxia and Naïve animals. …”