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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Evaluation of light-activated Ru(II) prodrugs and their photoproducts as potential anti-cancer agents
Published 2020“…All complexes reduced significantly tumor growth 3 weeks post treatment when compared to non-treated mice. …”
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Characterization of Dse1 a candida albicans cells wall protein. (c2009)
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Agent Productivity Modeling in a Call Center Domain Using Attentive Convolutional Neural Networks
Published 2020“…In this paper, we propose an objective framework for modeling agent productivity for real estate call centers based on speech signal processing. …”
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Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
Published 2022“…Our results illustrated that the increasing levels of Cd in the sand, significantly (P < 0.05) decreased shoot length, root length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, germination percentage, germination index, mean germination time, time to 50% germination, chlorophyll a, chlorophyll b, total chlorophyll and carotenoid contents in all genotypes of B. oleracea. …”
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A comprehensive design and rating study of evaporative coolers and condensers. Part I. Performance evaluation
Published 2020“…It is demonstrated that thermal effectiveness of the evaporative heat exchangers degrades significantly with time indicating that, for a low risk level (pZ0.01), there is about 66.7% decrease in effectiveness for the given fouling model. …”
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
Published 2024“…Fish fed with CURNPS at various levels exhibited remarkable increase in digestive enzymes (amylase and lipase), immune markers (immunoglobulin G (IgG), lysozyme and phagocytic indices), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)). A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …”
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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
Published 2019“…Unlike NRP-1, circulating PlGF was significantly increased (<i>p</i> = 0.014) in patients with a pathological complete response (pCR). …”
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Multi-Agent Meta Reinforcement Learning for Reliable and Low-Latency Distributed Inference in Resource-Constrained UAV Swarms
Published 2025“…<p dir="ltr">The integration of unmanned aerial vehicles (UAVs) in the Industrial Internet of Things (IIoT) for smart city applications has been gaining significant attention. UAV swarms are increasingly employed to monitor ground-based IIoT devices in smart cities, offering valuable support to situation-awareness IoT applications, such as surveillance, traffic management, and emergency response. …”
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Bond Strength Development of Ambient-Cured Sustainable Geopolymer Mortar to Concrete Substrate
Published 2025“…Nevertheless, the bond strength degraded dramatically when the bonding agent was applied to the concrete substrate. The SEM and roughness analyses were valuable techniques employed for interpreting the unexpected effect of the bonding agent on the bond strength between the FA/GGBS-based geopolymer mortar and concrete substrate.…”
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Peer-to-Peer Trade and the Sharing Economy at Distribution Level: A Review of the Literature
Published 2023“…In addition, the full achievement of the P2P energy trading potential requires a global response from stakeholders to ensure widespread acceptance and adoption. Game theory and agent-based modeling can effectively address these challenges and facilitate the successful implementation of P2P energy trading.…”
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”
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Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient?
Published 2022“…The X. strumarium exhibits late vegetative and reproductive phenology at higher altitudes, enabling them to occupy an empty niche and benefit from decreased competition for resource acquisition. The lower altitude plants show a higher growth rate (stem size increase, number of leaves, and leaf area) due to the higher nutrient availability. …”
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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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masterThesis