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Association Between Hypothyroidism and Hepatocellular Carcinoma: A Case-Control Study in the United States
Published 2009“…Hypothyroidism has been associated with nonalcoholic steatohepatitis; however, the association between thyroid diseases and hepatocellular carcinoma (HCC) in men and women has not been well established. …”
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Association of genetic polymorphisms in FTO with Overweight/Obesity and Type 2 Diabetes in the Lebanese Population
Published 2021“…On the other hand, the studied FTO variants were not significantly associated with T2DM. The present results, reported for the first time in Lebanon, provide insights about risk factors and chronic disease prevention for Middle Eastern populations.…”
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Incidence and Association of Uveitis with COVID-19 Vaccination: A Systematic Review and Meta-Analysis
Published 2024“…The overall incidence of uveitis was 0.016% (95% CI: 0.010 to 0.026). No significant association was found between vaccination and the onset of uveitis (Relative Risk: 1.45 (95% CI: 0.82 to 2.57, <i>p</i> = 0.12) from four studies. …”
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Bifidobacterium reduction is associated with high blood pressure in children with type 1 diabetes mellitus
Published 2021“…We can conclude that the reduction in the abundance of genus Bifidobacterium could play a significant role in elevating the BP in pediatric T1DM subjects. …”
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Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment
Published 2018“…Low TRIM28 epithelium to stroma ratios were associated with elevated levels of caspases 3 and 7 in stroma (p = 0.041 and p = 0.036) and an increased signaling pathway similarity in stromal cells with 81 significant Spearman correlations (ρ ≥ 0.75, p ≤ 0.01).…”
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Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis
Published 2022“…Microbial dysbiosis caused by RV infection may significantly influence disease prognosis and the development of other chronic diseases. …”
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Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19
Published 2021“…As a result, several antithrombotic modalities have been implicated in the treatment of this disease. This study aimed to identify if therapeutic anticoagulation (TAC) or concurrent use of antiplatelet and anticoagulants was associated with an improved outcome in this patient population. …”
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Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestry
Published 2022“…We observed an enrichment of BasalMyo tumors in AA patients (38 vs 16.5% in EA, p = 1.30E − 10), associated with a significant worse overall (hazard ratio (HR) = 2.39, p = 0.02) and disease-specific survival (HR = 2.57, p = 0.03). …”
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System biology approaches identified novel biomarkers and their signaling pathways involved in renal cell carcinoma with different human diseases
Published 2022“…Initially, the study identified 385 up-regulated genes and 338 down-regulated genes involved with RCC. OB, chronic kidney disease (CKD), type 2 diabetes (T2D), and HCV significantly shared 28, 14, 5, and 3 genes, respectively. …”
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Family-Based Genome-Wide Association Study of Autism Spectrum Disorder in Middle Eastern Families
Published 2021“…Additionally, three of the top associated SNPs were significantly associated with gene expression. …”
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Knowledge, attitude, and practice of physicians regarding pain management in patients with Sickle cell disease
Published 2023“…<p dir="ltr">Sickle cell disease (SCD) is a hemoglobin disorder inherited in an autosomal recessive pattern. …”
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The role of preoperative transfusion in sickle cell disease, a systematic review and meta-analysis
Published 2024“…Preoperative transfusion in SCD was associated with a higher bleeding risk but a similar risk in other outcomes compared to conservative strategies. …”
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Genetic susceptibility to coronary artery disease in type 2 diabetic patients. (c2010)
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Parental consanguinity and family history of coronary artery disease strongly predict early stenosis
Published 2010“…Conclusions Family history of CAD and smoking are strongly associated with young age at diagnosis. Furthermore, parental consanguinity in the presence of family history lowers the age of disease diagnosis significantly for CAD, emphasizing the role of strong genetic and cultural CAD modifiers. …”
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Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
Published 2021“…Objective: Normal aging is often associated with cognitive deterioration in older adults, but the prevalence of cognitive decline like cognitive impairment, Alzheimer’s disease and dementia has been increasing lately. …”
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Thrombophilic genetic anomalies and their association with dialysis initiation age in a cohort of Lebanese hemodialysis patients
Published 2018“…CONCLUSIONS:Our results revealed a polygenic thrombophilic profile in our population of Lebanese patients with end-stage renal disease. This profile showed a strong association between early dialysis initiation and specific homozygous cardiovascular disease gene mutations. …”
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Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits
Published 2020“…<p dir="ltr">DNA methylation and blood circulating proteins have been associated with many complex disorders, but the underlying disease-causing mechanisms often remain unclear. …”
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The effect of self-reported flossing behavior on cardiovascular disease events and mortality Findings from the 2009-2016 National Health and Nutrition Examination Surveys
Published 2025“…Participants in the not flossing group had significantly elevated CRP levels, even after multivariable adjustments. …”
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