Potentially inappropriate home medications among older patients with cardiovascular disease admitted to a cardiology service in USA حسب Sheikh-Taha, Marwan

"…The proportion of PIMS was 20% of all medications reported, with an average of 2.4 PIM per patient, and 87.4% of patients were receiving at least one PIM. Significant association was found between use of PIMs and number of home medications, female gender, and number and types of comorbidities. …"
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Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review حسب Mousa Hussein (14137052)

"…However, increased risk of infections is one of the most important concerns associated with these agents. Reactivation of tuberculosis and fungal infections have emerged as significant infective complications of anti-TNF-α therapy. …"

The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000) حسب Jabre, Mazen Gerges

"…The management of this disease is symptomatic, mainly based on the use of levodopa. …"
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The I allele of the angiotensin converting enzyme I/D polymorphism confers protection against coronary artery disease حسب Abchee, Antoine

"…Background: Mutations in genes regulating lipid metabolism, vasoactivity, and coagulation are important modulators of coronary artery disease (CAD). Objective: This study investigated the association between allelic variants of the angiotensin converting enzyme (ACE), methytetrahydrofolate reductase, plasminogen activator inhibitor-1 and factor V genes and CAD. …"
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A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction حسب Gillian Douglas (7759118)

"…<h3>Aims</h3><p dir="ltr">Genome-wide association studies (GWAS) have consistently identified an association between coronary artery disease (CAD) and a locus on chromosome 10 containing a single gene, JCAD (formerly KIAA1462). …"

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease حسب Nour K. Majbour (8809316)

"…<p dir="ltr">Several studies reported an association between CSF alpha-synuclein (α-syn) and tau in Alzheimer’s disease (AD), and demonstrated the significance of α-syn in improving the diagnostic sensitivity/specificity of classical AD CSF biomarkers. …"

Circulating lipid levels and risk of coronary artery disease in a large group of patients undergoing coronary angiography حسب Deeb, Mary E.

"…We tested if dyslipidemia is a risk factor for coronary artery disease in the Lebanese population, and studied the role of the total cholesterol/HDL cholesterol (TC/HDL-C) ratio as a biological marker of coronary artery disease. …"
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Vitamin D₃ metabolite ratio as an indicator of vitamin D status and its association with diabetes complications حسب Lina H. M. Ahmed (9571561)

"…VMR-₃ associated with hypertension (p < 0.05), dyslipidemia (p < 0.001) and coronary artery disease (p < 0.05).…"

The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells حسب Maram Hasan (6672440)

The potential protective role of vitamin D and calcium supplements in reducing cardiovascular disease risk among elderly patients with osteopenia حسب Ramada R. Khasawneh (6837734)

"…These two conditions are considered independent of each other and age-related diseases. The aim of this study is to investigate the association between low bone mineral density (BMD) and cardiovascular disease (CVD) incidents, and the effect of vitamin D and calcium supplement on the incidence of CVD in patients with low BMD.…"

10-year cardiovascular disease risk and its predictors: a comparison between healthcare workers and the general public in Qatar حسب Sami Abdeen (14779537)

"…The study aimed to compare the 10-year atherosclerotic cardiovascular disease (ASCVD) risk between the general public and HCWs in Qatar. …"

The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption حسب Sachin Wani (11704868)

"…<p dir="ltr">Paget's disease of bone (PDB) is characterized by focal increases in bone remodelling. …"

A cross-sectional analysis of zinc and copper levels and their relationship to cardiovascular disease risk markers in Qatar biobank participants حسب Abdelhamid Kerkadi (10724304)

"…<p dir="ltr">Cardiovascular diseases (CVD) are the leading cause of mortality and morbidity worldwide. …"

Genetic evaluation of cardiomyopathies in Qatar identifies enrichment of pathogenic sarcomere gene variants and possible founder disease mutations in the Arabs حسب Kholoud N. Al‐Shafai (18459009)

"…</p><h3>Conclusion</h3><p dir="ltr">We identified or replicated at least four recurrent variants among cardiomyopathy patients, which could be founder disease mutations in the Arabic population, including a frameshift variant (c.1371_1381dupTATCCAGTTAT) of unknown significance in the FKTN gene which seems to cause DCM in homozygosity, and HCM in heterozygosity. …"

T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility حسب Hirbli, Kamal

"…Genome-wide association studies (GWAS) of multiple populations with distinctive genetic and lifestyle backgrounds are crucial to the understanding of Type 2 Diabetes Mellitus (T2DM) pathophysiology. …"
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Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing حسب Mohamad Saad (214545)

"…</p><h3>Methods</h3><p dir="ltr">We conducted a genome-wide association study for coronary heart disease in a Middle Eastern cohort using whole genome sequencing and assessed the performance of 6 PRSs developed with methods including LDpred (PGS000296), metaGRS (PGS000018), Pruning and Thresholding (PGS000337), and an EnsemblePRS we developed. …"

Tumor-Infiltrating Lymphoid Cells in Colorectal Cancer Patients with Varying Disease Stages and Microsatellite Instability-High/Stable Tumors حسب Salman M. Toor (8854751)

"…We investigated the expression of immune checkpoints (ICs) on lymphoid populations within the CRC TME and compared with cells from normal colon tissues using samples from 50 patients with varying disease stages. We found that the levels of B cells, T cells, and NK cells were similar, IC-expressing CD4+ and CD4+CD8+ double positive T cells were higher, while CD8+ T cells and CD4−CD8− double negative T cells were significantly lower in CRC tumors. …"

Clinical characteristics and outcomes of patients with TSH-secreting pituitary adenoma and Graves’ disease - a case report and systematic review حسب Adeel Ahmad Khan (14152953)

"…</p><h3>Conclusion</h3><p dir="ltr">TSHoma and GD can co-exist, and it is essential to identify this rare association as it can significantly impact treatment strategies.…"

Genome-Wide Association Study in a Lebanese Cohort Confirms PHACTR1 as a Major Determinant of Coronary Artery Stenosis حسب Hager, Jorg

"…The association was replicated in an additional 2,547 individuals (OR = 1.31, p = 8.85×10−6), leading to genome-wide significant association in a combined analysis (OR = 1.34, p = 8.02×10−10). …"
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Revisiting high-density lipoprotein cholesterol in cardiovascular disease: Is too much of a good thing always a good thing? حسب Mohammad Al Zein (20090700)

"…Despite the correlation between low high-density lipoprotein cholesterol (HDLC) and heightened CVD risk, HDL-raising therapies have yet to showcase significant clinical benefits. Furthermore, evidence from epidemiological and genetic studies reveals that not only low HDL-C levels, but also very high levels of HDL-C are linked to increased risk of CVD. …"