Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf by Xue Bai (129175)

“…Oxidative stress and lipid metabolism disorder-induced myocardial cell damage are part of the pathogenesis of DCM. In this study, we investigated the effects of alpha-mangostin (A-MG), a natural antioxidant extracted from mangosteen peel, on in vitro and in vivo DCM models.…”

Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). by Hong Yan Huang (20135965)

“…P4HA3 and Ki-67 were decreased in the knockdown groups by siRNA compared to the NC group. …”

Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach. by DIMITRIOS KIMOGLOU (20499350)

“…<br>Chronic stress disrupts the apoptotic process and contributes to<br>tumorigenesis. In particular, we seek to illustrate the epigenetic influence of stress on genes that control apoptosis, as well as the significance of the HPA axis as a therapeutic target for restoring cellular equilibrium. …”

Comparisons of separability and variance of evidence distributions when noise and variability are manipulated independently for the 4-layer CNN across the three experiments. by Medha Shekhar (19502698)

“…Comparisons using two-sided, pairwise t-tests showed that separability of evidence distributions increased significantly from the low- to high-contrast condition whereas the variance of evidence distribution decreased from the low- to high-contrast conditions for all experiments except Experiment 3. …”

A Proposal for Implementation of Multi-Factor Authentication (MFA) System for Enhanced Security By Stephen Mikah Makoshi by Stephen Mikah Makoshi (20998469)

“…<b>Reduced Reliance on Passwords</b>: Decreased risk of security incidents related to passwords.…”

Changes of wind direction, wind speed and specific <i>orf2</i> amplicons during typhoon events for a range of years (2019–2020, n by Kuang-Yueh Chen (21071954)

“…Shades of blue, from dark (6-8 m/sec, largest) to light (0-2 m/sec, smallest), divided into 4 intervals, represent decreasing average wind speeds per hour (A). Comparison of aerosol concentrations (median values) between the north and south sides of the hills is illustrated (B, left), and the comparison of average northwesterly wind speeds per hours (median values) between the same regions, during typhoon landing, is illustrated (B, right). …”

Caffeine induces proteome-wide changes in a Rob-dependent manner. by Christoph Binsfeld (21763112)

“…Horizontal and vertical lines correspond to p-value = 0.05 and log₂(fold-change) = 0, respectively. n refers to the total number of proteins detected. The double-sided Fisher’s exact test p-value for enrichment of OMPs among significantly decreased proteins is shown. …”

Stepwise increments in stimulus amplitude alter the information content of post-EOD spike distributions. by Alejo Rodríguez-Cattáneo (19713314)

“…Upper (A) and lower (B) rows correspond to experiments in which the stimulus was decreased and increased, respectively. To test the hypothesis that, for each unit, the step change in stimulus amplitude adds information with respect to a control condition, individual one-sided sign-rank tests were applied (p-values are indicated in between the brackets). …”

Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf by Rongrong Huang (819212)

“…Background<p>Viral pneumonia is the most common and lethal pandemic disease, but there are no broad-spectrum antiviral drugs with high genetic barriers to resistance. To elucidate the mechanisms of viral pneumonia progression and potential targets for its treatment.…”

Impact of moderate-to-severe ulcerative colitis and Crohn’s disease on sexual activity: United States and European patient perspectives from the communicating needs and features of... by Marla C. Dubinsky (10978320)

“…Of these, most US (UC: 63%, CD: 69%) and European (UC: 53%, CD: 56%) patients reported avoiding or decreasing sexual activity due to UC or CD in the past 3 months; however, the proportion was significantly greater among US patients (<i>p</i> <.05). …”

Data Sheet 1_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx by Alexia Giovanazzi (16816139)

“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. Regarding app usage, data entries decreased significantly from the first quarter to the second quarter but subsequently stabilised (p = 0.001). …”

Data Sheet 2_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx by Alexia Giovanazzi (16816139)

“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. Regarding app usage, data entries decreased significantly from the first quarter to the second quarter but subsequently stabilised (p = 0.001). …”

Negative regulation of reassortant canine influenza virus replication and key site identification in porcine and ferret bronchial epithelial cell lines by Jingjing Guo (393650)

“…<p>The segmented nature and high mutability of the influenza virus RNA genome facilitate rapid mutation and reassortment, allowing the virus to breach host barriers and migrate between different species, potentially leading to unpredictable influenza outbreaks. …”

Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer by Xiaoxiao Sun (20589448)

“…Statistical comparisons between groups were based on the integrated confluence over time (area under curve; AUC), using one-sided Mann–Whitney tests. The significance of the results is indicated by symbols: *, <i>P</i> ≤ 0.05; **, <i>P</i> ≤ 0.01; ****, <i>P</i> ≤ 0.0001.…”

LRIG1 and CDK6 expression in the lateral ventricular wall cells by Hyung-song Nam (8914220)

“…Although the <i>Cdk6</i> mRNA decreases significantly in the neuroblasts, the DCX+ neuroblasts still show a lot of td-sfGFP immunoreactivity.…”