Showing 161 - 180 results of 94,140 for search '(( significant based cancer ) OR ( significant ((degs decrease) OR (we decrease)) ))', query time: 2.59s Refine Results
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    Supplementary Material for: Validation of a urine- based proteomics test to predict clinically significant prostate cancer: complementing mpMRI pathway by Frantzi M. (20149656)

    Published 2024
    “…A major clinical need is to accurately predict clinically significant PCa (csPCa). A proteomics-based 19-biomarker model (19-BM) was previously developed using capillary electrophoresis-mass spectrometry (CE-MS) and validated in 1000 patients at risk for PCa. …”
  8. 168

    Data Sheet 2_A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer.pdf by Amith Rangarajan (21978383)

    Published 2025
    “…With the explosion of clinical NGS data and the concurrent availability of protein structures through the Protein Data Bank and protein models through programs such as AlphaFold, there exists an unprecedented opportunity to use structural information to help standardize NGS analysis with the overall goal of advancing personalized cancer therapy.</p>Methods<p>Using the Catalogue of Somatic Mutations in Cancer (COSMIC), the largest curated database of clinical cancer mutations, we mapped thousands of missense mutations in the kinase and juxtamembrane (JM) domains of 48 receptor tyrosine kinases (RTKs) onto structurally aligned kinase structures, then clustered known activating mutations along with VUSs based on proximity in three-dimensional structure. …”
  9. 169

    Image_1_Significance of monocyte infiltration in patients with gastric cancer: A combined study based on single cell sequencing and TCGA.jpeg by Wei Xu (28953)

    Published 2022
    “…Despite some improvements, the prognosis of patients with gastric cancer is still not accurately predicted.</p>Methods<p>Based on single cell sequencing data, we conducted a detailed analysis of gastric cancer patients and normal tissues to determine the role of monocytes in the progression of gastric cancer. …”
  10. 170

    Data Sheet 1_A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer.pdf by Amith Rangarajan (21978383)

    Published 2025
    “…With the explosion of clinical NGS data and the concurrent availability of protein structures through the Protein Data Bank and protein models through programs such as AlphaFold, there exists an unprecedented opportunity to use structural information to help standardize NGS analysis with the overall goal of advancing personalized cancer therapy.</p>Methods<p>Using the Catalogue of Somatic Mutations in Cancer (COSMIC), the largest curated database of clinical cancer mutations, we mapped thousands of missense mutations in the kinase and juxtamembrane (JM) domains of 48 receptor tyrosine kinases (RTKs) onto structurally aligned kinase structures, then clustered known activating mutations along with VUSs based on proximity in three-dimensional structure. …”
  11. 171

    Data Sheet 1_Construction of a clinically significant prostate cancer risk prediction model based on traditional diagnostic methods.docx by Wen-Tong Ji (20457248)

    Published 2024
    “…Objectives<p>to construct a prediction model for clinically significant prostate cancer (csPCa) based on prostate-specific antigen (PSA) levels, digital rectal examination (DRE), and transrectal ultrasonography (TRUS).…”
  12. 172

    Data Sheet 2_Construction of a clinically significant prostate cancer risk prediction model based on traditional diagnostic methods.docx by Wen-Tong Ji (20457248)

    Published 2024
    “…Objectives<p>to construct a prediction model for clinically significant prostate cancer (csPCa) based on prostate-specific antigen (PSA) levels, digital rectal examination (DRE), and transrectal ultrasonography (TRUS).…”
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    Table_3_Significance of monocyte infiltration in patients with gastric cancer: A combined study based on single cell sequencing and TCGA.xlsx by Wei Xu (28953)

    Published 2022
    “…Despite some improvements, the prognosis of patients with gastric cancer is still not accurately predicted.</p>Methods<p>Based on single cell sequencing data, we conducted a detailed analysis of gastric cancer patients and normal tissues to determine the role of monocytes in the progression of gastric cancer. …”
  15. 175

    Table_1_Significance of monocyte infiltration in patients with gastric cancer: A combined study based on single cell sequencing and TCGA.xlsx by Wei Xu (28953)

    Published 2022
    “…Despite some improvements, the prognosis of patients with gastric cancer is still not accurately predicted.</p>Methods<p>Based on single cell sequencing data, we conducted a detailed analysis of gastric cancer patients and normal tissues to determine the role of monocytes in the progression of gastric cancer. …”
  16. 176

    Table_2_Significance of monocyte infiltration in patients with gastric cancer: A combined study based on single cell sequencing and TCGA.xlsx by Wei Xu (28953)

    Published 2022
    “…Despite some improvements, the prognosis of patients with gastric cancer is still not accurately predicted.</p>Methods<p>Based on single cell sequencing data, we conducted a detailed analysis of gastric cancer patients and normal tissues to determine the role of monocytes in the progression of gastric cancer. …”
  17. 177

    Base-case analysis. by Yiping An (20609789)

    Published 2025
    “…Scenario analyses conducted over a time horizon extending from 10 to 30 years showed that the ICER decreased significantly with longer follow-up, gradually approaching the 0.51GDP threshold and remaining below the 0.90 GDP threshold throughout the analysis.…”
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