Table 1_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx حسب Oliver Küppers (22742732)

"…RNA-seq analysis of Tnfaip6-deficient mMSCs revealed decreased expression of several genes that are critical for bone formation and healing, including matrix metallopeptidase 13, decorin, membrane metallopeptidase, and integrin binding sialoprotein. …"

Image 3_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... حسب Qinghong Lin (14162640)

"…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …"

Image 2_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... حسب Qinghong Lin (14162640)

"…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …"

Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx حسب Oliver Küppers (22742732)

"…RNA-seq analysis of Tnfaip6-deficient mMSCs revealed decreased expression of several genes that are critical for bone formation and healing, including matrix metallopeptidase 13, decorin, membrane metallopeptidase, and integrin binding sialoprotein. …"

Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf حسب Oliver Küppers (22742732)

"…RNA-seq analysis of Tnfaip6-deficient mMSCs revealed decreased expression of several genes that are critical for bone formation and healing, including matrix metallopeptidase 13, decorin, membrane metallopeptidase, and integrin binding sialoprotein. …"

DataSheet1_HER2 expression in different cell lines at different inoculation sites assessed by [52Mn]Mn-DOTAGA(anhydride)-trastuzumab.docx حسب Toàn Minh Ngô (21195116)

"…Significantly higher tumor-to-blood and tumor-to-muscle ratios were observed in HER2-positive ectopic tumors compared to HER2-negative tumors but only at 4 and 24 h; the differences were likely due to non-specific binding of the tracer. …"

Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx حسب Oliver Küppers (22742732)

"…RNA-seq analysis of Tnfaip6-deficient mMSCs revealed decreased expression of several genes that are critical for bone formation and healing, including matrix metallopeptidase 13, decorin, membrane metallopeptidase, and integrin binding sialoprotein. …"

Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf حسب Oliver Küppers (22742732)

"…RNA-seq analysis of Tnfaip6-deficient mMSCs revealed decreased expression of several genes that are critical for bone formation and healing, including matrix metallopeptidase 13, decorin, membrane metallopeptidase, and integrin binding sialoprotein. …"

Deciphering the involvement of norepinephrine and β-adrenergic receptor subtypes in glucose induced insulin secretion: an integrated <i>in silico</i> and <i>in vitro</i> exploratio... حسب Vijayalakshmi Gangadhara (20481150)

"…The nonselective β-AR antagonist propranolol significantly decreased (<i>p</i> < 0.01)insulin secretion, suggesting alternative interactions with β1-AR and β2-AR despite lacking hydrogen bonds. …"

Data Sheet 1_Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease.docx حسب Zongjiang Zhao (21215822)

"…Molecular docking showed that they had good biological binding capacity. In vitro cell experiments further showed that quercetin, luteolin and kaempferol could significantly activate the cells and reduce the mRNA levels of PTGS2, AKT1, MMP9, EGFR, MMP2, and ANGPTL4, and increase the level of FGFR1, SIRT3 and the glucocorticoid receptor (GR).…"

Data Sheet 1_Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway.pdf حسب Zulipikaer Wusiman (20852138)

"…In addition, transcriptome analysis indicated that GA likely acts through the mitogen-activated protein kinase (MAPK) signaling pathway. GA has a strong binding affinity for important targets.GA significantly increased the expression of genes such as mapk8b, mapk14a, mapk3, mitf, tyr, tyrp1b, tyrp1a, dct, and oca2, and decreased the expression of genes such as expression of genes such as raf1 and egfr. …"

Supplementary Material for: Identifying novel inflammatory protein biomarkers and drug targets of inflammatory bowel disease by integrating Mendelian randomization, bioinformatics,... حسب Wang F. (3215361)

"…Results: By integrating data from two cohorts, we demonstrated that genetically predicted CD40 (odds ratio [OR] = 0.878, 95% confidence interval [CI] = 0.838-0.919) and C-X-C motif chemokine ligand (CXCL)5 (OR = 0.884, 95%CI = 0.841-0.930) decreased IBD risk. However, genetically predicted CXCL9 (OR = 1.184, 95%CI = 1.084-1.294), Interleukin (IL)-18 (OR = 1.140, 95%CI = 1.076-1.208), CD6 (OR = 1.096, 95%CI = 1.045-1.150), and 4E-binding protein 1 (4E-BP1) (OR = 1.154, 95%CI = 1.070-1.244) increased IBD risk. …"

Data Sheet 6_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf حسب Sadia Hamera (22524803)

"…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"

Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx حسب Ningning Chen (509273)

"…</p>Results<p>IGFBP5 was significantly downregulated after PM exposure. Functional investigations demonstrated that IGFBP5 downregulation exacerbated PM-induced oxidative damage, as evidenced by elevated levels of reactive oxygen species (ROS) and malondialdehyde, as well as decreased levels of superoxide dismutase 2 (SOD2). …"

Data Sheet 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.pdf حسب Yan Fan (575147)

"…By binding to IGF1, IGFBP5 prevented its interaction with IGF1R. …"

Table 1_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.doc... حسب Yiping Cao (1229856)

"…Pharmacological activation of local PVT A_2AR with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …"

Image 2_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.tiff حسب Sadia Hamera (22524803)

"…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"

Table 5_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx حسب Yan Fan (575147)

"…By binding to IGF1, IGFBP5 prevented its interaction with IGF1R. …"

Graphic abstract of the study. حسب Donglin Yang (490406)

"…The results showed that the expression of circRNAs in serum exosomes of DN patients was significantly down-regulated, and hsa_circ_0006382 and hsa_circ_0019539 targeted the expression of FGF9 by binding to miR-34a-5p, miR-766-3p, miR-147a and miR-27a-3p. …"

Image 1_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.tif حسب Yiping Cao (1229856)

"…Pharmacological activation of local PVT A_2AR with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …"