يعرض 1 - 20 نتائج من 20,948 نتيجة بحث عن '(( significant binding poses ) OR ( significant ((new decrease) OR (mean decrease)) ))', وقت الاستعلام: 0.55s تنقيح النتائج
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    B2 decreases glycolytic intermediates in cells. حسب Craig Eyster (392633)

    منشور في 2025
    "…Other abbreviations: HGA, DL-hydroxyglutaric acid; PEP, phosphoenolpyruvic acid; 3-PGA, 3-phosphoglyceric acid; G3P; glyceraldehyde 3-phosphate; Data (n = 5) are shown as mean±SD. Not significant (ns): **<i>P</i> ≤ 0.01, ****<i>P</i> ≤ 0.0001by one-way ANOVA with multiple comparison of the mean of each test group to the mean of the vehicle control. …"
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    Scoring Conformational Metastability of Macrocyclic Peptides with Binding Pose Metadynamics حسب Ryan Dykstra (5418395)

    منشور في 2025
    "…In our benchmark calculations on macrocyclic peptide data sets where chemical modifications can be expected to influence the stability of the binding pose, our solution-state binding pose metadynamics workflow, which estimates conformational metastability of the bioactive state, agrees with more rigorous REST2 simulations while using significantly less computational resources. …"
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    Impact of Different Automated Binding Pose Generation Approaches on Relative Binding Free Energy Simulations حسب Daniel Cappel (382223)

    منشور في 2020
    "…We then studied the effect of binding pose generation on the accuracy of RBFE predictions using six ligand series from five pharmaceutically relevant protein targets. …"
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    Prb1 overexpression decreased APCs in ESCRT-mutant cells after nitrogen starvation. حسب Zulin Wu (4451572)

    منشور في 2022
    "…The percentage of cells containing GFP in vacuoles (shown in panel A) was quantified as the mean +/- STD. Over 600 cells were counted for each strain. …"
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