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significant decrease » significantly increased (Expand Search)
significant bit » significant bias (Expand Search), significant hits (Expand Search), significant i (Expand Search)
bit decrease » point decrease (Expand Search), bfrt decreased (Expand Search), fid decreased (Expand Search)
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20181
Table 2_Profiling of small RNAs derived from tomato brown rugose fruit virus in infected Solanum lycopersicum plants by deep sequencing.xls
Published 2025“…Seven potential target genes were selected for qRT-PCR analysis, confirming that their transcript accumulation significantly decreased in the leaves of tomato plants infected with ToBRFV. …”
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20182
Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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20183
Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis
Published 2025“…Furthermore, LPS and FeSO<sub>4</sub> significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. …”
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20184
Supplementary Material for: Words versus strands: Reliability and stability of concordance rates of self-reported and hair-analyzed substance use of young adults over time
Published 2024“…Hair analysis-derived 3-month prevalence rates of cocaine (9%/23%) and ketamine (2%/6%) strongly increased over time, while decreasing for codeine (11%/8%). …”
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20185
Optimisation of read depth, DNA quantity, and unique alternate observation threshold.
Published 2025“…I: The CV of variant size quantitation across independent replicates, which displayed a strong negative correlation to variant size (dotted lines indicate 95% confidence interval). J-L: Increasing unique alternative observation (UAO) thresholds for variant calls increased detection rate of rare variants (J), but markedly decreased the number of variants passing the threshold (K) and therefore reduced detection of true positive variants in reference standards (L). …”
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20186
Data Sheet 1_Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis...
Published 2025“…HOMA-IR also decreased with every additional minute of weekly interval duration (β;=-0.06; 95%CI: -0.08 to -0.04; p<0.001). …”
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20187
Data Sheet 1_The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma.docx
Published 2025“…</p>Results<p>The invasion and migration capacities of nasopharyngeal carcinoma cells decreased significantly after CENPN knockdown, whereas the overexpression of CENPN significantly promoted the invasion and metastasis abilities of nasopharyngeal carcinoma cells. …”
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20188
The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach.
Published 2025“…</p><p dir="ltr">- Somatisation and Organ Response: Chronic stress is frequently somatised by increased autonomic nervous system activity, which causes malfunction in important organs, increases inflammation, and increases the risk of neoplastic diseases.…”
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20189
Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice
Published 2025“…Adolescent neuronal density was significantly decreased in exposed males’ distal dorsal subiculum (<i>p</i> < .0001, g = −0.8). …”
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20190
Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets
Published 2025“…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …”
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20191
Prognostic indicators and survival rates in vulvar cancer: insights from a retrospective study
Published 2025“…Additionally, a tumour size exceeding 4 cm in diameter was significantly linked with decreased OS (<i>p</i> = .001). …”
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20192
Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
Published 2025“…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …”
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20193
Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
Published 2025“…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …”
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20194
Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip
Published 2025“…Th1/Th17 cytokines significantly inhibited the high calcium-induced synthesis of phospholipids (PCs, PEs, SMs), and short-chain ceramides, while the synthesis of ceramides with medium to long carbon chains was upregulated. …”
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20195
Phage–antibiotic interactions are determined by the antibiotic, not the phage.
Published 2025“…While the phage amplification rate increases with nitrofurantoin (synergy), it decreases with doxycycline (antagonism). …”
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20196
Table 1_Global burden of pneumoconiosis from 1990 to 2021: a comprehensive analysis of incidence, mortality, and socio-demographic inequalities in 204 countries and territories.doc...
Published 2025“…These rates were generally elevated in low-income and lower-middle-income regions, where males exhibited significantly higher ASIR and ASDR compared to females. …”
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20197
Table 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…”
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20198
Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx
Published 2025“…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…”
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20199
Image 1_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif
Published 2025“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”
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20200
Table 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.docx
Published 2025“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR<sub>PDI</sub> = 0.85; 95% CI: 0.80–0.90; pooled HR<sub>hPDI</sub> = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”