يعرض 7,301 - 7,320 نتائج من 7,363 نتيجة بحث عن '(( significant burden decrease ) OR ( significant ((shape decrease) OR (we decrease)) ))', وقت الاستعلام: 0.44s تنقيح النتائج
  1. 7301

    Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX حسب Cataldo Martucci (3117069)

    منشور في 2024
    "…In a murine house dust mite (HDM) model of asthma exacerbated by influenza virus A (IAV) (H3N3), CHF6297 (0.1 mg/kg, i.n.) significantly decreased airway neutrophilia compared to vehicle-treated IAV/HDM-challenged mice. …"
  2. 7302

    Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

    منشور في 2025
    "…The miR-10a-5p, miR-24-3p, and miR-130a-3p, were not detected in raw buffalo milk. Therefore, we simulated the gastrointestinal digestion using INFOGEST 2.0 and extracted extracellular vesicles from the digest. …"
  3. 7303

    Data Sheet 1_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx حسب Xinxin Wang (134010)

    منشور في 2024
    "…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …"
  4. 7304

    Data Sheet 1_A multimodal approach for establishing ACTL6A and ERCC1 as chemoresistance genes in locally advanced head and neck cancer.docx حسب Raushan Kumar Chaudhary (15664043)

    منشور في 2025
    "…The median expressions of ERCC1 were significantly increased (p < 0.001) after 50% (0.19) and 100% CRT (0.23) compared to the baseline value (0.14), whereas ACTL6A expression decreased from 4.77 to 3.87 after 50% CRT (p < 0.05) and increased to 5.43 after 100% CRT. …"
  5. 7305

    Table 1_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx حسب Xinxin Wang (134010)

    منشور في 2024
    "…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …"
  6. 7306

    Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 حسب Mete Keçeci (20479508)

    منشور في 2024
    "…Curcumin (Cur) is a natural polyphenol compound with powerful antioxidant and antiapoptotic effects. In this study we investigate the effects of Cur on MTX-induced ovarian damage.…"
  7. 7307

    Data Sheet 3_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx حسب Xinxin Wang (134010)

    منشور في 2024
    "…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …"
  8. 7308

    Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip حسب Alessia Cavallo (13036581)

    منشور في 2025
    "…Introduction<p>Abnormalities of keratinocyte differentiation and impairment of permeability barrier are features of inflammatory skin diseases driven by Th1/Th17 and Th2 immune response, such as psoriasis and atopic dermatitis. We aimed at identifying the signature of the Th1/Th17 and Th2 environments on keratinocytes, focusing on the expression of genes involved in the lipid metabolism and profiles of abundance of lipid metabolites.…"
  9. 7309

    Table1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.docx حسب Adam D. Price (19842741)

    منشور في 2024
    "…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…"
  10. 7310

    Image2_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg حسب Adam D. Price (19842741)

    منشور في 2024
    "…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…"
  11. 7311

    Image3_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg حسب Adam D. Price (19842741)

    منشور في 2024
    "…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…"
  12. 7312

    Image1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg حسب Adam D. Price (19842741)

    منشور في 2024
    "…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…"
  13. 7313

    Table2_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…</p>Methods<p>Therefore, our study aimed to investigate the causal relationships between plasma lipidome and four types of pancreatitis by conducting a bidirectional, two-sample Mendelian randomization (MR) analysis. We obtained genetic variants associated with 179 lipid species from a Genome-wide association analysis of plasma lipidome. …"
  14. 7314

    Table4_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…</p>Methods<p>Therefore, our study aimed to investigate the causal relationships between plasma lipidome and four types of pancreatitis by conducting a bidirectional, two-sample Mendelian randomization (MR) analysis. We obtained genetic variants associated with 179 lipid species from a Genome-wide association analysis of plasma lipidome. …"
  15. 7315

    Table1_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…</p>Methods<p>Therefore, our study aimed to investigate the causal relationships between plasma lipidome and four types of pancreatitis by conducting a bidirectional, two-sample Mendelian randomization (MR) analysis. We obtained genetic variants associated with 179 lipid species from a Genome-wide association analysis of plasma lipidome. …"
  16. 7316

    DataSheet1_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.pdf حسب Runzhou Ma (19758996)

    منشور في 2024
    "…</p>Methods<p>Therefore, our study aimed to investigate the causal relationships between plasma lipidome and four types of pancreatitis by conducting a bidirectional, two-sample Mendelian randomization (MR) analysis. We obtained genetic variants associated with 179 lipid species from a Genome-wide association analysis of plasma lipidome. …"
  17. 7317

    Table5_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…</p>Methods<p>Therefore, our study aimed to investigate the causal relationships between plasma lipidome and four types of pancreatitis by conducting a bidirectional, two-sample Mendelian randomization (MR) analysis. We obtained genetic variants associated with 179 lipid species from a Genome-wide association analysis of plasma lipidome. …"
  18. 7318

    Table3_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…</p>Methods<p>Therefore, our study aimed to investigate the causal relationships between plasma lipidome and four types of pancreatitis by conducting a bidirectional, two-sample Mendelian randomization (MR) analysis. We obtained genetic variants associated with 179 lipid species from a Genome-wide association analysis of plasma lipidome. …"
  19. 7319

    Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... حسب Xuan Chen (158617)

    منشور في 2025
    "…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …"
  20. 7320

    Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets حسب Karl Knipper (15016346)

    منشور في 2025
    "…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …"